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Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3).

Branham-O'Connor M, Robichaux WG 3rd, Zhang XK, Cho H, Kehrl JH, Lanier SM, Blumer JB.

J Biol Chem. 2014 Apr 11;289(15):10738-47. doi: 10.1074/jbc.M113.515031. Epub 2014 Feb 26.


Regulation of Chemokine Signal Integration by Activator of G-Protein Signaling 4 (AGS4).

Robichaux WG 3rd, Branham-O'Connor M, Hwang IY, Vural A, Kehrl JH, Blumer JB.

J Pharmacol Exp Ther. 2017 Mar;360(3):424-433. doi: 10.1124/jpet.116.238436. Epub 2017 Jan 6.


Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.

Oner SS, An N, Vural A, Breton B, Bouvier M, Blumer JB, Lanier SM.

J Biol Chem. 2010 Oct 29;285(44):33949-58. doi: 10.1074/jbc.M110.138073. Epub 2010 Aug 17.


Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteins.

Bernard ML, Peterson YK, Chung P, Jourdan J, Lanier SM.

J Biol Chem. 2001 Jan 12;276(2):1585-93.


Translocation of activator of G-protein signaling 3 to the Golgi apparatus in response to receptor activation and its effect on the trans-Golgi network.

Oner SS, Vural A, Lanier SM.

J Biol Chem. 2013 Aug 16;288(33):24091-103. doi: 10.1074/jbc.M112.444505. Epub 2013 Jun 14.


AGS3 inhibits GDP dissociation from galpha subunits of the Gi family and rhodopsin-dependent activation of transducin.

Natochin M, Lester B, Peterson YK, Bernard ML, Lanier SM, Artemyev NO.

J Biol Chem. 2000 Dec 29;275(52):40981-5.


The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins.

An N, Blumer JB, Bernard ML, Lanier SM.

J Biol Chem. 2008 Sep 5;283(36):24718-28. doi: 10.1074/jbc.M803497200. Epub 2008 Jun 19.


An essential role for RGS protein/Gαi2 interactions in B lymphocyte-directed cell migration and trafficking.

Hwang IY, Park C, Harrison K, Boularan C, Galés C, Kehrl JH.

J Immunol. 2015 Mar 1;194(5):2128-39. doi: 10.4049/jimmunol.1401952. Epub 2015 Jan 23.


The chemokine SDF-1, stromal cell-derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4.

D'Apuzzo M, Rolink A, Loetscher M, Hoxie JA, Clark-Lewis I, Melchers F, Baggiolini M, Moser B.

Eur J Immunol. 1997 Jul;27(7):1788-93.


Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits.

De Vries L, Fischer T, Tronchère H, Brothers GM, Strockbine B, Siderovski DP, Farquhar MG.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14364-9.


Influence of cytosolic AGS3 on receptor--G protein coupling.

Ma H, Peterson YK, Bernard ML, Lanier SM, Graber SG.

Biochemistry. 2003 Jul 8;42(26):8085-93.


G Protein-coupled receptor kinase-6 interacts with activator of G protein signaling-3 to regulate CXCR2-mediated cellular functions.

Singh V, Raghuwanshi SK, Smith N, Rivers EJ, Richardson RM.

J Immunol. 2014 Mar 1;192(5):2186-94. doi: 10.4049/jimmunol.1301875. Epub 2014 Feb 7.


Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3.

Peterson YK, Bernard ML, Ma H, Hazard S 3rd, Graber SG, Lanier SM.

J Biol Chem. 2000 Oct 27;275(43):33193-6.


Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling.

Norment AM, Bogatzki LY, Gantner BN, Bevan MJ.

J Immunol. 2000 Jan 15;164(2):639-48.

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