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Items: 1 to 20 of 96

1.

Design, synthesis and properties of artificial nucleic acids from (R)-4-amino-butane-1,3-diol.

Li P, Sun J, Su M, Yang X, Tang X.

Org Biomol Chem. 2014 Apr 14;12(14):2263-72. doi: 10.1039/c3ob42291g.

PMID:
24569918
2.

Design, synthesis, biophysical and primer extension studies of novel acyclic butyl nucleic acid (BuNA).

Kumar V, Gore KR, Pradeepkumar PI, Kesavan V.

Org Biomol Chem. 2013 Sep 21;11(35):5853-65. doi: 10.1039/c3ob41244j.

PMID:
23903805
3.

Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2'-C-piperazino-UNA monomer.

Jensen TB, Henriksen JR, Rasmussen BE, Rasmussen LM, Andresen TL, Wengel J, Pasternak A.

Bioorg Med Chem. 2011 Aug 15;19(16):4739-45. doi: 10.1016/j.bmc.2011.06.087. Epub 2011 Jul 7.

PMID:
21795054
4.

Unlocking G-quadruplex: Effect of unlocked nucleic acid on G-quadruplex stability.

Agarwal T, Kumar S, Maiti S.

Biochimie. 2011 Oct;93(10):1694-700. doi: 10.1016/j.biochi.2011.05.036. Epub 2011 Jun 21.

PMID:
21718749
5.

Unlocked nucleic acids with a pyrene-modified uracil: synthesis, hybridization studies, fluorescent properties and i-motif stability.

Perlíková P, Karlsen KK, Pedersen EB, Wengel J.

Chembiochem. 2014 Jan 3;15(1):146-56.

PMID:
24501777
6.

Duplex formation of the simplified nucleic acid GNA.

Schlegel MK, Peritz AE, Kittigowittana K, Zhang L, Meggers E.

Chembiochem. 2007 May 25;8(8):927-32.

PMID:
17465439
7.

Effects of six-membered carbohydrate rings on structure, stability, and kinetics of G-quadruplexes.

Zhou J, Abramov M, Liu F, Amrane S, Bourdoncle A, Herdewijn P, Mergny JL.

Chemistry. 2013 Oct 18;19(43):14719-25. doi: 10.1002/chem.201301743. Epub 2013 Sep 11.

PMID:
24027098
8.

Synthesis and properties of the simplified nucleic acid glycol nucleic acid.

Meggers E, Zhang L.

Acc Chem Res. 2010 Aug 17;43(8):1092-102. doi: 10.1021/ar900292q.

PMID:
20405911
9.

Investigating the role of T7 and T12 residues on the biological properties of thrombin-binding aptamer: enhancement of anticoagulant activity by a single nucleobase modification.

Borbone N, Bucci M, Oliviero G, Morelli E, Amato J, D'Atri V, D'Errico S, Vellecco V, Cirino G, Piccialli G, Fattorusso C, Varra M, Mayol L, Persico M, Scuotto M.

J Med Chem. 2012 Dec 13;55(23):10716-28. doi: 10.1021/jm301414f. Epub 2012 Nov 19.

PMID:
23126678
10.

Synthesis and biophysical properties of (L)-aTNA based G-quadruplexes.

Kumar V, Gothelf KV.

Org Biomol Chem. 2016 Feb 7;14(5):1540-4. doi: 10.1039/c5ob02525g.

PMID:
26731694
11.

Synthesis and properties of 2'-O,4'-C-methyleneoxymethylene bridged nucleic acid.

Hari Y, Obika S, Ohnishi R, Eguchi K, Osaki T, Ohishi H, Imanishi T.

Bioorg Med Chem. 2006 Feb 15;14(4):1029-38. Epub 2005 Oct 5.

PMID:
16213732
12.

Synthesis and properties of nucleic acid analogues consisting of a benzene-phosphate backbone.

Ueno Y, Kato T, Sato K, Ito Y, Yoshida M, Inoue T, Shibata A, Ebihara M, Kitade Y.

J Org Chem. 2005 Sep 30;70(20):7925-35.

PMID:
16277312
13.

Pyrene-modified unlocked nucleic acids: synthesis, thermodynamic studies, and fluorescent properties.

Karlsen KK, Pasternak A, Jensen TB, Wengel J.

Chembiochem. 2012 Mar 5;13(4):590-601. doi: 10.1002/cbic.201100689. Epub 2012 Feb 7.

PMID:
22315188
14.
15.

Synthesis and RNA binding selectivity of oligonucleotides modified with five-atom thioacetamido nucleic acid backbone structures.

Gogoi K, Gunjal AD, Phalgune UD, Kumar VA.

Org Lett. 2007 Jul 5;9(14):2697-700. Epub 2007 Jun 7.

PMID:
17552532
16.

Synthesis of a novel nucleic acid mimic: P-boranomethylphosphonate.

Lin J, Shaw BR.

Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1325-8.

PMID:
11563014
17.
18.

Conformation and thermostability of oligonucleotide d(GGTTGGTGTGGTTGG) containing thiophosphoryl internucleotide bonds at different positions.

Zaitseva M, Kaluzhny D, Shchyolkina A, Borisova O, Smirnov I, Pozmogova G.

Biophys Chem. 2010 Jan;146(1):1-6. doi: 10.1016/j.bpc.2009.09.011. Epub 2009 Oct 1.

PMID:
19846249
19.

Incorporation of porphyrin acetylides into duplexes of the simplified nucleic acid GNA.

Zhou H, Johnson AT, Wiest O, Zhang L.

Org Biomol Chem. 2011 Apr 21;9(8):2840-9. doi: 10.1039/c0ob00439a. Epub 2011 Mar 2.

PMID:
21365112
20.

Modulation of pyrene fluorescence in DNA probes depends upon the nature of the conformationally restricted nucleotide.

Honcharenko D, Zhou C, Chattopadhyaya J.

J Org Chem. 2008 Apr 4;73(7):2829-42. doi: 10.1021/jo702747w. Epub 2008 Mar 11.

PMID:
18331060

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