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Items: 1 to 20 of 133

1.

A novel pathway links oxidative stress to loss of insulin growth factor-2 (IGF2) imprinting through NF-κB activation.

Yang B, Wagner J, Damaschke N, Yao T, Wuerzberger-Davis SM, Lee MH, Svaren J, Miyamoto S, Jarrard DF.

PLoS One. 2014 Feb 18;9(2):e88052. doi: 10.1371/journal.pone.0088052. eCollection 2014.

2.

A loss of insulin-like growth factor-2 imprinting is modulated by CCCTC-binding factor down-regulation at senescence in human epithelial cells.

Fu VX, Schwarze SR, Kenowski ML, Leblanc S, Svaren J, Jarrard DF.

J Biol Chem. 2004 Dec 10;279(50):52218-26. Epub 2004 Oct 7.

3.

Tissue-specific insulator function at H19/Igf2 revealed by deletions at the imprinting control region.

Ideraabdullah FY, Thorvaldsen JL, Myers JA, Bartolomei MS.

Hum Mol Genet. 2014 Dec 1;23(23):6246-59. doi: 10.1093/hmg/ddu344. Epub 2014 Jul 2.

4.

Aging and cancer-related loss of insulin-like growth factor 2 imprinting in the mouse and human prostate.

Fu VX, Dobosy JR, Desotelle JA, Almassi N, Ewald JA, Srinivasan R, Berres M, Svaren J, Weindruch R, Jarrard DF.

Cancer Res. 2008 Aug 15;68(16):6797-802. doi: 10.1158/0008-5472.CAN-08-1714.

5.

CTCF binding at the insulin-like growth factor-II (IGF2)/H19 imprinting control region is insufficient to regulate IGF2/H19 expression in human tissues.

Ulaner GA, Yang Y, Hu JF, Li T, Vu TH, Hoffman AR.

Endocrinology. 2003 Oct;144(10):4420-6. Epub 2003 Jul 10.

PMID:
12960026
6.

Epigenetic regulation of Igf2/H19 imprinting at CTCF insulator binding sites.

Yang Y, Hu JF, Ulaner GA, Li T, Yao X, Vu TH, Hoffman AR.

J Cell Biochem. 2003 Dec 1;90(5):1038-55.

PMID:
14624463
7.

Promoter histone H3K27 methylation in the control of IGF2 imprinting in human tumor cell lines.

Li T, Chen H, Li W, Cui J, Wang G, Hu X, Hoffman AR, Hu J.

Hum Mol Genet. 2014 Jan 1;23(1):117-28. doi: 10.1093/hmg/ddt405. Epub 2013 Aug 19.

8.

Aberrant epigenetic modifications in the CTCF binding domain of the IGF2/H19 gene in prostate cancer compared with benign prostate hyperplasia.

Paradowska A, Fenic I, Konrad L, Sturm K, Wagenlehner F, Weidner W, Steger K.

Int J Oncol. 2009 Jul;35(1):87-96.

PMID:
19513555
9.

IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switch.

Li T, Vu TH, Ulaner GA, Littman E, Ling JQ, Chen HL, Hu JF, Behr B, Giudice L, Hoffman AR.

Mol Hum Reprod. 2005 Sep;11(9):631-40. Epub 2005 Oct 11.

PMID:
16219628
10.

CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2.

Kurukuti S, Tiwari VK, Tavoosidana G, Pugacheva E, Murrell A, Zhao Z, Lobanenkov V, Reik W, Ohlsson R.

Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10684-9. Epub 2006 Jun 30.

11.

Mutation of a single CTCF target site within the H19 imprinting control region leads to loss of Igf2 imprinting and complex patterns of de novo methylation upon maternal inheritance.

Pant V, Kurukuti S, Pugacheva E, Shamsuddin S, Mariano P, Renkawitz R, Klenova E, Lobanenkov V, Ohlsson R.

Mol Cell Biol. 2004 Apr;24(8):3497-504.

12.

Role of CTCF binding sites in the Igf2/H19 imprinting control region.

Szabó PE, Tang SH, Silva FJ, Tsark WM, Mann JR.

Mol Cell Biol. 2004 Jun;24(11):4791-800.

13.

Interruption of intrachromosomal looping by CCCTC binding factor decoy proteins abrogates genomic imprinting of human insulin-like growth factor II.

Zhang H, Niu B, Hu JF, Ge S, Wang H, Li T, Ling J, Steelman BN, Qian G, Hoffman AR.

J Cell Biol. 2011 May 2;193(3):475-87. doi: 10.1083/jcb.201101021.

14.

CTCF maintains differential methylation at the Igf2/H19 locus.

Schoenherr CJ, Levorse JM, Tilghman SM.

Nat Genet. 2003 Jan;33(1):66-9. Epub 2002 Dec 2.

PMID:
12461525
15.

Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site.

Ulaner GA, Vu TH, Li T, Hu JF, Yao XM, Yang Y, Gorlick R, Meyers P, Healey J, Ladanyi M, Hoffman AR.

Hum Mol Genet. 2003 Mar 1;12(5):535-49.

PMID:
12588801
16.

CTCF is the master organizer of domain-wide allele-specific chromatin at the H19/Igf2 imprinted region.

Han L, Lee DH, Szabó PE.

Mol Cell Biol. 2008 Feb;28(3):1124-35. Epub 2007 Nov 26.

17.

Loss of imprinting of insulin-like growth factor-II in Wilms' tumor commonly involves altered methylation but not mutations of CTCF or its binding site.

Cui H, Niemitz EL, Ravenel JD, Onyango P, Brandenburg SA, Lobanenkov VV, Feinberg AP.

Cancer Res. 2001 Jul 1;61(13):4947-50.

18.

Frequent IGF2/H19 domain epigenetic alterations and elevated IGF2 expression in epithelial ovarian cancer.

Murphy SK, Huang Z, Wen Y, Spillman MA, Whitaker RS, Simel LR, Nichols TD, Marks JR, Berchuck A.

Mol Cancer Res. 2006 Apr;4(4):283-92.

19.

Prohibitin 1 Regulates the H19-Igf2 Axis and Proliferation in Hepatocytes.

Ramani K, Mavila N, Ko KS, Mato JM, Lu SC.

J Biol Chem. 2016 Nov 11;291(46):24148-24159. Epub 2016 Sep 29.

PMID:
27687727
20.

Targeted tumor gene therapy based on loss of IGF2 imprinting.

Pan Y, He B, Li T, Zhu C, Zhang L, Wang B, Xu Y, Qu L, Hoffman AR, Wang S, Hu J.

Cancer Biol Ther. 2010 Aug 1;10(3):290-8. Epub 2010 Aug 21.

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