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Mechanical allodynia induced by nucleoside reverse transcriptase inhibitor is suppressed by p55TNFSR mediated by herpes simplex virus vector through the SDF1α/CXCR4 system in rats.

Huang W, Zheng W, Ouyang H, Yi H, Liu S, Zeng W, Levitt RC, Candiotti KA, Lubarsky DA, Hao S.

Anesth Analg. 2014 Mar;118(3):671-80. doi: 10.1213/ANE.0000000000000079.


IL-10 mediated by herpes simplex virus vector reduces neuropathic pain induced by HIV gp120 combined with ddC in rats.

Zheng W, Huang W, Liu S, Levitt RC, Candiotti KA, Lubarsky DA, Hao S.

Mol Pain. 2014 Jul 30;10:49. doi: 10.1186/1744-8069-10-49.


HSV-mediated p55TNFSR reduces neuropathic pain induced by HIV gp120 in rats through CXCR4 activity.

Huang W, Zheng W, Liu S, Zeng W, Levitt RC, Candiotti KA, Lubarsky DA, Hao S.

Gene Ther. 2014 Mar;21(3):328-36. doi: 10.1038/gt.2013.90. Epub 2014 Jan 23.


Interleukin 10 mediated by herpes simplex virus vectors suppresses neuropathic pain induced by human immunodeficiency virus gp120 in rats.

Zheng W, Huang W, Liu S, Levitt RC, Candiotti KA, Lubarsky DA, Hao S.

Anesth Analg. 2014 Sep;119(3):693-701. doi: 10.1213/ANE.0000000000000311.


Gene Transfer of Glutamic Acid Decarboxylase 67 by Herpes Simplex Virus Vectors Suppresses Neuropathic Pain Induced by Human Immunodeficiency Virus gp120 Combined with ddC in Rats.

Kanao M, Kanda H, Huang W, Liu S, Yi H, Candiotti KA, Lubarsky DA, Levitt RC, Hao S.

Anesth Analg. 2015 Jun;120(6):1394-404. doi: 10.1213/ANE.0000000000000729.


Upregulation of Chemokine CXCL12 in the Dorsal Root Ganglia and Spinal Cord Contributes to the Development and Maintenance of Neuropathic Pain Following Spared Nerve Injury in Rats.

Bai L, Wang X, Li Z, Kong C, Zhao Y, Qian JL, Kan Q, Zhang W, Xu JT.

Neurosci Bull. 2016 Feb;32(1):27-40. doi: 10.1007/s12264-015-0007-4. Epub 2016 Jan 19.


CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy.

Bhangoo SK, Ren D, Miller RJ, Chan DM, Ripsch MS, Weiss C, McGinnis C, White FA.

Brain Behav Immun. 2007 Jul;21(5):581-91. Epub 2007 Feb 9.


SDF1-CXCR4 signaling contributes to persistent pain and hypersensitivity via regulating excitability of primary nociceptive neurons: involvement of ERK-dependent Nav1.8 up-regulation.

Yang F, Sun W, Yang Y, Wang Y, Li CL, Fu H, Wang XL, Yang F, He T, Chen J.

J Neuroinflammation. 2015 Nov 24;12:219. doi: 10.1186/s12974-015-0441-2.


TNFα is involved in neuropathic pain induced by nucleoside reverse transcriptase inhibitor in rats.

Zheng X, Ouyang H, Liu S, Mata M, Fink DJ, Hao S.

Brain Behav Immun. 2011 Nov;25(8):1668-76. doi: 10.1016/j.bbi.2011.06.010. Epub 2011 Jun 28.


Spatio-temporal changes of SDF1 and its CXCR4 receptor in the dorsal root ganglia following unilateral sciatic nerve injury as a model of neuropathic pain.

Dubový P, Klusáková I, Svízenská I, Brázda V.

Histochem Cell Biol. 2010 Mar;133(3):323-37. doi: 10.1007/s00418-010-0675-0. Epub 2010 Feb 3.


Contralateral neuropathic pain and neuropathology in dorsal root ganglion and spinal cord following hemilateral nerve injury in rats.

Hatashita S, Sekiguchi M, Kobayashi H, Konno S, Kikuchi S.

Spine (Phila Pa 1976). 2008 May 20;33(12):1344-51. doi: 10.1097/BRS.0b013e3181733188.


CXCL12/CXCR4 chemokine signaling in spinal glia induces pain hypersensitivity through MAPKs-mediated neuroinflammation in bone cancer rats.

Hu XM, Liu YN, Zhang HL, Cao SB, Zhang T, Chen LP, Shen W.

J Neurochem. 2015 Feb;132(4):452-63. doi: 10.1111/jnc.12985. Epub 2015 Jan 26. Erratum in: J Neurochem. 2015 Feb;132(4):487.


CXCL12 in astrocytes contributes to bone cancer pain through CXCR4-mediated neuronal sensitization and glial activation in rat spinal cord.

Shen W, Hu XM, Liu YN, Han Y, Chen LP, Wang CC, Song C.

J Neuroinflammation. 2014 Apr 16;11:75. doi: 10.1186/1742-2094-11-75.


Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats.

Ledeboer A, Jekich BM, Sloane EM, Mahoney JH, Langer SJ, Milligan ED, Martin D, Maier SF, Johnson KW, Leinwand LA, Chavez RA, Watkins LR.

Brain Behav Immun. 2007 Jul;21(5):686-98. Epub 2006 Dec 15.


Inhibition of Mitochondrial Fission Protein Reduced Mechanical Allodynia and Suppressed Spinal Mitochondrial Superoxide Induced by Perineural Human Immunodeficiency Virus gp120 in Rats.

Kanda H, Liu S, Iida T, Yi H, Huang W, Levitt RC, Lubarsky DA, Candiotti KA, Hao S.

Anesth Analg. 2016 Jan;122(1):264-72. doi: 10.1213/ANE.0000000000000962.


Characterization of rodent models of HIV-gp120 and anti-retroviral-associated neuropathic pain.

Wallace VC, Blackbeard J, Segerdahl AR, Hasnie F, Pheby T, McMahon SB, Rice AS.

Brain. 2007 Oct;130(Pt 10):2688-702. Epub 2007 Aug 30.


Gene transfer to interfere with TNFalpha signaling in neuropathic pain.

Hao S, Mata M, Glorioso JC, Fink DJ.

Gene Ther. 2007 Jul;14(13):1010-6. Epub 2007 Apr 19.


The RNA-binding protein HuD promotes spinal GAP43 overexpression in antiretroviral-induced neuropathy.

Sanna MD, Quattrone A, Mello T, Ghelardini C, Galeotti N.

Exp Neurol. 2014 Nov;261:343-53. doi: 10.1016/j.expneurol.2014.05.017. Epub 2014 May 24.


Expression of monocyte chemoattractant protein-1 and its induction by tumor necrosis factor receptor 1 in sensory neurons in the ventral rhizotomy model of neuropathic pain.

Jeon SM, Sung JK, Cho HJ.

Neuroscience. 2011 Sep 8;190:354-66. doi: 10.1016/j.neuroscience.2011.06.036. Epub 2011 Jun 25.


Crosstalk between astrocytic CXCL12 and microglial CXCR4 contributes to the development of neuropathic pain.

Luo X, Tai WL, Sun L, Pan Z, Xia Z, Chung SK, Cheung CW.

Mol Pain. 2016 Mar 8;12. pii: 1744806916636385. doi: 10.1177/1744806916636385. Print 2016.

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