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Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells.

Shi K, An J, Shan L, Jiang Q, Li F, Ci Y, Wu P, Duan J, Hui K, Yang Y, Xu C.

Cell Death Dis. 2014 Feb 20;5:e1071. doi: 10.1038/cddis.2014.34.


Heat shock protein 90-mediated inactivation of nuclear factor-κB switches autophagy to apoptosis through becn1 transcriptional inhibition in selenite-induced NB4 cells.

Jiang Q, Wang Y, Li T, Shi K, Li Z, Ma Y, Li F, Luo H, Yang Y, Xu C.

Mol Biol Cell. 2011 Apr 15;22(8):1167-80. doi: 10.1091/mbc.E10-10-0860. Epub 2011 Feb 23.


Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells.

Jiang Q, Li F, Shi K, Wu P, An J, Yang Y, Xu C.

Cell Death Dis. 2014 May 29;5:e1270. doi: 10.1038/cddis.2014.200.


ATM-dependent nuclear accumulation of IKK-alpha plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin.

Yoshida K, Ozaki T, Furuya K, Nakanishi M, Kikuchi H, Yamamoto H, Ono S, Koda T, Omura K, Nakagawara A.

Oncogene. 2008 Feb 14;27(8):1183-8. Epub 2007 Aug 13.


The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells.

Wu P, Shi KJ, An JJ, Ci YL, Li F, Hui KY, Yang Y, Xu CM.

Cell Death Dis. 2014 Feb 27;5:e1085. doi: 10.1038/cddis.2014.13.


Stabilization of p73 by nuclear IkappaB kinase-alpha mediates cisplatin-induced apoptosis.

Furuya K, Ozaki T, Hanamoto T, Hosoda M, Hayashi S, Barker PA, Takano K, Matsumoto M, Nakagawara A.

J Biol Chem. 2007 Jun 22;282(25):18365-78. Epub 2007 Apr 23.


Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin.

Momeny M, Zakidizaji M, Ghasemi R, Dehpour AR, Rahimi-Balaei M, Abdolazimi Y, Ghavamzadeh A, Alimoghaddam K, Ghaffari SH.

Med Oncol. 2010 Sep;27(3):833-42. doi: 10.1007/s12032-009-9294-9. Epub 2009 Sep 10.


ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells.

Ci Y, Shi K, An J, Yang Y, Hui K, Wu P, Shi L, Xu C.

Cell Death Dis. 2014 Nov 27;5:e1542. doi: 10.1038/cddis.2014.506.


A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

Hinz M, Stilmann M, Arslan SÇ, Khanna KK, Dittmar G, Scheidereit C.

Mol Cell. 2010 Oct 8;40(1):63-74. doi: 10.1016/j.molcel.2010.09.008.


Silencing survivin splice variant 2B leads to antitumor activity in taxane--resistant ovarian cancer.

Vivas-Mejia PE, Rodriguez-Aguayo C, Han HD, Shahzad MM, Valiyeva F, Shibayama M, Chavez-Reyes A, Sood AK, Lopez-Berestein G.

Clin Cancer Res. 2011 Jun 1;17(11):3716-26. doi: 10.1158/1078-0432.CCR-11-0233. Epub 2011 Apr 21.


Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.

Zhang L, Zhang W, Wang YF, Liu B, Zhang WF, Zhao YF, Kulkarni AB, Sun ZJ.

Cell Death Dis. 2015 May 28;6:e1771. doi: 10.1038/cddis.2015.139.


ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy.

Maskey D, Yousefi S, Schmid I, Zlobec I, Perren A, Friis R, Simon HU.

Nat Commun. 2013;4:2130. doi: 10.1038/ncomms3130.


Oncoprotein E7 from beta human papillomavirus 38 induces formation of an inhibitory complex for a subset of p53-regulated promoters.

Saidj D, Cros MP, Hernandez-Vargas H, Guarino F, Sylla BS, Tommasino M, Accardi R.

J Virol. 2013 Nov;87(22):12139-50. doi: 10.1128/JVI.01047-13. Epub 2013 Sep 4.


Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells.

Humbert M, Mueller C, Fey MF, Tschan MP.

Leuk Res. 2012 Dec;36(12):1552-6. doi: 10.1016/j.leukres.2012.08.024. Epub 2012 Sep 13.


p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death.

Crighton D, O'Prey J, Bell HS, Ryan KM.

Cell Death Differ. 2007 Jun;14(6):1071-9. Epub 2007 Feb 16.


α-Tomatine-mediated anti-cancer activity in vitro and in vivo through cell cycle- and caspase-independent pathways.

Chao MW, Chen CH, Chang YL, Teng CM, Pan SL.

PLoS One. 2012;7(9):e44093. doi: 10.1371/journal.pone.0044093. Epub 2012 Sep 6.


An essential role for the Id1/PI3K/Akt/NFkB/survivin signalling pathway in promoting the proliferation of endothelial progenitor cells in vitro.

Li W, Wang H, Kuang CY, Zhu JK, Yu Y, Qin ZX, Liu J, Huang L.

Mol Cell Biochem. 2012 Apr;363(1-2):135-45. doi: 10.1007/s11010-011-1166-x. Epub 2011 Dec 3.


Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin.

Abe A, Kokuba H.

Oncol Rep. 2013 Apr;29(4):1333-42. doi: 10.3892/or.2013.2242. Epub 2013 Jan 18.


Downregulation of active IKK beta by Ro52-mediated autophagy.

Niida M, Tanaka M, Kamitani T.

Mol Immunol. 2010 Aug;47(14):2378-87. doi: 10.1016/j.molimm.2010.05.004. Epub 2010 Jun 2.

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