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Items: 1 to 20 of 75

1.

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.

Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stütz AM, Wang X, Gallo M, Garzia L, Zayne K, Zhang X, Ramaswamy V, Jäger N, Jones DT, Sill M, Pugh TJ, Ryzhova M, Wani KM, Shih DJ, Head R, Remke M, Bailey SD, Zichner T, Faria CC, Barszczyk M, Stark S, Seker-Cin H, Hutter S, Johann P, Bender S, Hovestadt V, Tzaridis T, Dubuc AM, Northcott PA, Peacock J, Bertrand KC, Agnihotri S, Cavalli FM, Clarke I, Nethery-Brokx K, Creasy CL, Verma SK, Koster J, Wu X, Yao Y, Milde T, Sin-Chan P, Zuccaro J, Lau L, Pereira S, Castelo-Branco P, Hirst M, Marra MA, Roberts SS, Fults D, Massimi L, Cho YJ, Van Meter T, Grajkowska W, Lach B, Kulozik AE, von Deimling A, Witt O, Scherer SW, Fan X, Muraszko KM, Kool M, Pomeroy SL, Gupta N, Phillips J, Huang A, Tabori U, Hawkins C, Malkin D, Kongkham PN, Weiss WA, Jabado N, Rutka JT, Bouffet E, Korbel JO, Lupien M, Aldape KD, Bader GD, Eils R, Lichter P, Dirks PB, Pfister SM, Korshunov A, Taylor MD.

Nature. 2014 Feb 27;506(7489):445-50. doi: 10.1038/nature13108. Epub 2014 Feb 19.

2.

Epigenomic analysis of Alu repeats in human ependymomas.

Xie H, Wang M, Bonaldo Mde F, Rajaram V, Stellpflug W, Smith C, Arndt K, Goldman S, Tomita T, Soares MB.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6952-7. doi: 10.1073/pnas.0913836107. Epub 2010 Mar 29.

3.

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.

Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, Viale A, Morris LG, Huse JT, Mellinghoff IK, Chan TA.

Nature. 2012 Feb 15;483(7390):479-83. doi: 10.1038/nature10866.

4.

Epigenetic inactivation of MCJ (DNAJD1) in malignant paediatric brain tumours.

Lindsey JC, Lusher ME, Strathdee G, Brown R, Gilbertson RJ, Bailey S, Ellison DW, Clifford SC.

Int J Cancer. 2006 Jan 15;118(2):346-52.

5.

Gene silencing triggers polycomb repressive complex 2 recruitment to CpG islands genome wide.

Riising EM, Comet I, Leblanc B, Wu X, Johansen JV, Helin K.

Mol Cell. 2014 Aug 7;55(3):347-60. doi: 10.1016/j.molcel.2014.06.005. Epub 2014 Jul 3.

6.

The CpG island methylator phenotype correlates with long-range epigenetic silencing in colorectal cancer.

Karpinski P, Ramsey D, Grzebieniak Z, Sasiadek MM, Blin N.

Mol Cancer Res. 2008 Apr;6(4):585-91. doi: 10.1158/1541-7786.MCR-07-2158.

7.

Reversal of GSTP1 CpG island hypermethylation and reactivation of pi-class glutathione S-transferase (GSTP1) expression in human prostate cancer cells by treatment with procainamide.

Lin X, Asgari K, Putzi MJ, Gage WR, Yu X, Cornblatt BS, Kumar A, Piantadosi S, DeWeese TL, De Marzo AM, Nelson WG.

Cancer Res. 2001 Dec 15;61(24):8611-6.

8.

Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.

Tahara T, Yamamoto E, Madireddi P, Suzuki H, Maruyama R, Chung W, Garriga J, Jelinek J, Yamano HO, Sugai T, Kondo Y, Toyota M, Issa JP, Estécio MR.

Gastroenterology. 2014 Feb;146(2):530-38.e5. doi: 10.1053/j.gastro.2013.10.060. Epub 2013 Nov 6.

9.

Impact on prognosis of the regional distribution of MGMT methylation with respect to the CpG island methylator phenotype and age in glioma patients.

Mur P, Rodríguez de Lope Á, Díaz-Crespo FJ, Hernández-Iglesias T, Ribalta T, Fiaño C, García JF, Rey JA, Mollejo M, Meléndez B.

J Neurooncol. 2015 May;122(3):441-50. doi: 10.1007/s11060-015-1738-9. Epub 2015 Feb 15.

PMID:
25682093
10.

Methylation subtypes and large-scale epigenetic alterations in gastric cancer.

Zouridis H, Deng N, Ivanova T, Zhu Y, Wong B, Huang D, Wu YH, Wu Y, Tan IB, Liem N, Gopalakrishnan V, Luo Q, Wu J, Lee M, Yong WP, Goh LK, Teh BT, Rozen S, Tan P.

Sci Transl Med. 2012 Oct 17;4(156):156ra140. doi: 10.1126/scitranslmed.3004504.

11.

Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.

Rogers HA, Kilday JP, Mayne C, Ward J, Adamowicz-Brice M, Schwalbe EC, Clifford SC, Coyle B, Grundy RG.

Acta Neuropathol. 2012 May;123(5):711-25. doi: 10.1007/s00401-011-0904-1. Epub 2011 Nov 23.

12.

Intermediate- and low-methylation epigenotypes do not correspond to CpG island methylator phenotype (low and -zero) in colorectal cancer.

Karpinski P, Walter M, Szmida E, Ramsey D, Misiak B, Kozlowska J, Bebenek M, Grzebieniak Z, Blin N, Laczmanski L, Sasiadek MM.

Cancer Epidemiol Biomarkers Prev. 2013 Feb;22(2):201-8. doi: 10.1158/1055-9965.EPI-12-0157. Epub 2012 Nov 21.

13.

Identification of genes targeted by CpG island methylator phenotype in neuroblastomas, and their possible integrative involvement in poor prognosis.

Abe M, Watanabe N, McDonell N, Takato T, Ohira M, Nakagawara A, Ushijima T.

Oncology. 2008;74(1-2):50-60. doi: 10.1159/000139124. Epub 2008 Jun 11.

PMID:
18544995
14.

The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.

Goel A, Nagasaka T, Arnold CN, Inoue T, Hamilton C, Niedzwiecki D, Compton C, Mayer RJ, Goldberg R, Bertagnolli MM, Boland CR.

Gastroenterology. 2007 Jan;132(1):127-38. Epub 2006 Sep 20.

PMID:
17087942
15.

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma.

Wiestler B, Capper D, Sill M, Jones DT, Hovestadt V, Sturm D, Koelsche C, Bertoni A, Schweizer L, Korshunov A, Weiß EK, Schliesser MG, Radbruch A, Herold-Mende C, Roth P, Unterberg A, Hartmann C, Pietsch T, Reifenberger G, Lichter P, Radlwimmer B, Platten M, Pfister SM, von Deimling A, Weller M, Wick W.

Acta Neuropathol. 2014 Oct;128(4):561-71. doi: 10.1007/s00401-014-1315-x. Epub 2014 Jul 10.

PMID:
25008768
16.

Identification of a CpG island methylator phenotype in adrenocortical carcinomas.

Barreau O, Assié G, Wilmot-Roussel H, Ragazzon B, Baudry C, Perlemoine K, René-Corail F, Bertagna X, Dousset B, Hamzaoui N, Tissier F, de Reynies A, Bertherat J.

J Clin Endocrinol Metab. 2013 Jan;98(1):E174-84. doi: 10.1210/jc.2012-2993. Epub 2012 Oct 23.

PMID:
23093492
17.

IGFBP3 promoter methylation in colorectal cancer: relationship with microsatellite instability, CpG island methylator phenotype, and p53.

Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Kirkner GJ, Fuchs CS, Ogino S.

Neoplasia. 2007 Dec;9(12):1091-8.

18.

Aberrant CpG island methylation of multiple genes in ependymal tumors.

Alonso ME, Bello MJ, Gonzalez-Gomez P, Arjona D, de Campos JM, Gutierrez M, Rey JA.

J Neurooncol. 2004 Mar-Apr;67(1-2):159-65.

PMID:
15072463
19.

Remodeling epigenetic modifications at tumor suppressor gene promoters with bovine oocyte extract.

Wang Z, Yue Y, Han P, Sa R, Ren X, Wang J, Bai H, Yu H.

Cytotherapy. 2013 Sep;15(9):1164-73. doi: 10.1016/j.jcyt.2013.05.001. Epub 2013 Jun 22.

PMID:
23800731
20.

Molecular genetics of ependymomas and pediatric diffuse gliomas: a short review.

Nobusawa S, Hirato J, Yokoo H.

Brain Tumor Pathol. 2014 Oct;31(4):229-33. doi: 10.1007/s10014-014-0200-6. Epub 2014 Sep 3. Review.

PMID:
25182241

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