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Items: 1 to 20 of 153

1.

IL-6 and related cytokines as the critical lynchpins between inflammation and cancer.

Taniguchi K, Karin M.

Semin Immunol. 2014 Feb;26(1):54-74. doi: 10.1016/j.smim.2014.01.001. Epub 2014 Feb 16. Review.

PMID:
24552665
2.

Gene of the month: Interleukin 6 (IL-6).

Ataie-Kachoie P, Pourgholami MH, Richardson DR, Morris DL.

J Clin Pathol. 2014 Nov;67(11):932-7. doi: 10.1136/jclinpath-2014-202493. Epub 2014 Jul 16. Review.

PMID:
25031389
3.

Interleukin-6--a key regulator of colorectal cancer development.

Waldner MJ, Foersch S, Neurath MF.

Int J Biol Sci. 2012;8(9):1248-53. doi: 10.7150/ijbs.4614. Epub 2012 Oct 24. Review.

4.

Epithelial gp130/Stat3 functions: an intestinal signaling node in health and disease.

Ernst M, Thiem S, Nguyen PM, Eissmann M, Putoczki TL.

Semin Immunol. 2014 Feb;26(1):29-37. doi: 10.1016/j.smim.2013.12.006. Epub 2014 Jan 13. Review.

PMID:
24434062
5.

Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer.

Rose-John S, Scheller J, Elson G, Jones SA.

J Leukoc Biol. 2006 Aug;80(2):227-36. Epub 2006 May 17. Review.

PMID:
16707558
6.

The IL-6 feed-forward loop: a driver of tumorigenesis.

Chang Q, Daly L, Bromberg J.

Semin Immunol. 2014 Feb;26(1):48-53. doi: 10.1016/j.smim.2014.01.007. Epub 2014 Mar 6. Review.

PMID:
24613573
7.

Interleukin-6 trans-signaling and colonic cancer associated with inflammatory bowel disease.

Rose-John S, Mitsuyama K, Matsumoto S, Thaiss WM, Scheller J.

Curr Pharm Des. 2009;15(18):2095-103. Review.

PMID:
19519447
8.

The IL-6/sIL-6R complex as a novel target for therapeutic approaches.

Rose-John S, Waetzig GH, Scheller J, Grötzinger J, Seegert D.

Expert Opin Ther Targets. 2007 May;11(5):613-24. Review.

PMID:
17465721
9.

Interleukin-6 trans-signalling in chronic inflammation and cancer.

Scheller J, Ohnesorge N, Rose-John S.

Scand J Immunol. 2006 May;63(5):321-9. Review.

10.

Blocking the IL-6-STAT3 signaling pathway: potential liver cancer therapy.

Liu Y, Lin J.

Future Oncol. 2011 Feb;7(2):161-4. doi: 10.2217/fon.10.183. No abstract available.

PMID:
21345134
11.

New insights for IL-6 targeted therapy as an adjuvant treatment for non-small-cell lung cancer.

Zarogoulidis P, Yarmus L, Zarogoulidis K.

Ther Deliv. 2013 Oct;4(10):1221-3. doi: 10.4155/tde.13.95. No abstract available.

PMID:
24116905
12.

Interleukin-6: from basic biology to selective blockade of pro-inflammatory activities.

Scheller J, Garbers C, Rose-John S.

Semin Immunol. 2014 Feb;26(1):2-12. doi: 10.1016/j.smim.2013.11.002. Epub 2013 Dec 8. Review.

PMID:
24325804
13.

NF-κB and the link between inflammation and cancer.

DiDonato JA, Mercurio F, Karin M.

Immunol Rev. 2012 Mar;246(1):379-400. doi: 10.1111/j.1600-065X.2012.01099.x. Review.

PMID:
22435567
14.

Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeutics.

Goldberg JE, Schwertfeger KL.

Curr Drug Targets. 2010 Sep;11(9):1133-46. Review.

PMID:
20545607
15.

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer.

Shrimali D, Shanmugam MK, Kumar AP, Zhang J, Tan BK, Ahn KS, Sethi G.

Cancer Lett. 2013 Dec 1;341(2):139-49. doi: 10.1016/j.canlet.2013.08.023. Epub 2013 Aug 17. Review.

PMID:
23962559
16.

Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically.

Putoczki TL, Thiem S, Loving A, Busuttil RA, Wilson NJ, Ziegler PK, Nguyen PM, Preaudet A, Farid R, Edwards KM, Boglev Y, Luwor RB, Jarnicki A, Horst D, Boussioutas A, Heath JK, Sieber OM, Pleines I, Kile BT, Nash A, Greten FR, McKenzie BS, Ernst M.

Cancer Cell. 2013 Aug 12;24(2):257-71. doi: 10.1016/j.ccr.2013.06.017.

17.

The soluble Interleukin 6 receptor: generation and role in inflammation and cancer.

Chalaris A, Garbers C, Rabe B, Rose-John S, Scheller J.

Eur J Cell Biol. 2011 Jun-Jul;90(6-7):484-94. doi: 10.1016/j.ejcb.2010.10.007. Epub 2010 Dec 8. Review.

PMID:
21145125
18.

Cancer-related inflammation.

Candido J, Hagemann T.

J Clin Immunol. 2013 Jan;33 Suppl 1:S79-84. doi: 10.1007/s10875-012-9847-0. Epub 2012 Dec 9. Review.

PMID:
23225204
19.

In vitro reconstitution of recognition and activation complexes between interleukin-6 and gp130.

Chow D, Ho J, Nguyen Pham TL, Rose-John S, Garcia KC.

Biochemistry. 2001 Jun 26;40(25):7593-603.

PMID:
11412113
20.

[Interleukin-6 From molecular mechanisms of signal transduction to physiological properties and therapeutic targeting].

Drutskaya MS, Nosenko MA, Atretkhany KS, Efimov GA, Nedospasov SA.

Mol Biol (Mosk). 2015 Nov-Dec;49(6):937-43. doi: 10.7868/S0026898415060063. Review. Russian.

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