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Items: 1 to 20 of 90

1.

Mechanisms of Hg species induced toxicity in cultured human astrocytes: genotoxicity and DNA-damage response.

Pieper I, Wehe CA, Bornhorst J, Ebert F, Leffers L, Holtkamp M, Höseler P, Weber T, Mangerich A, Bürkle A, Karst U, Schwerdtle T.

Metallomics. 2014 Mar;6(3):662-71. doi: 10.1039/c3mt00337j. Epub 2014 Feb 19.

PMID:
24549367
2.

Toxicity of organic and inorganic mercury species in differentiated human neurons and human astrocytes.

Lohren H, Blagojevic L, Fitkau R, Ebert F, Schildknecht S, Leist M, Schwerdtle T.

J Trace Elem Med Biol. 2015 Oct;32:200-8. doi: 10.1016/j.jtemb.2015.06.008. Epub 2015 Jul 15.

PMID:
26302930
3.

Manganese inhibits poly(ADP-ribosyl)ation in human cells: a possible mechanism behind manganese-induced toxicity?

Bornhorst J, Ebert F, Hartwig A, Michalke B, Schwerdtle T.

J Environ Monit. 2010 Nov;12(11):2062-9. doi: 10.1039/c0em00252f. Epub 2010 Sep 6.

PMID:
20820627
4.

Molecular mechanisms of Mn induced neurotoxicity: RONS generation, genotoxicity, and DNA-damage response.

Bornhorst J, Meyer S, Weber T, Böker C, Marschall T, Mangerich A, Beneke S, Bürkle A, Schwerdtle T.

Mol Nutr Food Res. 2013 Jul;57(7):1255-69. doi: 10.1002/mnfr.201200758. Epub 2013 Mar 14.

PMID:
23495240
5.

Impact of copper on the induction and repair of oxidative DNA damage, poly(ADP-ribosyl)ation and PARP-1 activity.

Schwerdtle T, Hamann I, Jahnke G, Walter I, Richter C, Parsons JL, Dianov GL, Hartwig A.

Mol Nutr Food Res. 2007 Feb;51(2):201-10.

PMID:
17230584
6.

Impact of arsenite and its methylated metabolites on PARP-1 activity, PARP-1 gene expression and poly(ADP-ribosyl)ation in cultured human cells.

Walter I, Schwerdtle T, Thuy C, Parsons JL, Dianov GL, Hartwig A.

DNA Repair (Amst). 2007 Jan 4;6(1):61-70. Epub 2006 Sep 29.

PMID:
17011244
7.

Induction of poly(ADP-ribosyl)ation in the kidney after in vivo application of renal carcinogens.

McLaren J, Boulikas T, Vamvakas S.

Toxicology. 1994 Mar 11;88(1-3):101-12.

PMID:
8160192
8.

Poly(ADP-ribosyl)ation is a survival mechanism in cigarette smoke-induced and hydrogen peroxide-mediated cell death.

Kovács K, Erdélyi K, Hegedűs C, Lakatos P, Regdon Z, Bai P, Haskó G, Szabó E, Virág L.

Free Radic Biol Med. 2012 Nov 1;53(9):1680-8. doi: 10.1016/j.freeradbiomed.2012.08.579. Epub 2012 Aug 27.

PMID:
22964577
9.

Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells.

Weidele K, Kunzmann A, Schmitz M, Beneke S, Bürkle A.

Biochem Pharmacol. 2010 Oct 1;80(7):1103-12. doi: 10.1016/j.bcp.2010.06.010. Epub 2010 Jun 25.

PMID:
20599792
10.

Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells.

Ebert F, Leffers L, Weber T, Berndt S, Mangerich A, Beneke S, Bürkle A, Schwerdtle T.

J Trace Elem Med Biol. 2014 Apr;28(2):138-46. doi: 10.1016/j.jtemb.2013.06.004. Epub 2013 Jul 5.

PMID:
23994116
11.

Effect of poly(ADP-ribosyl)ation inhibitors on the genotoxic effects of the boron neutron capture reaction.

Oliveira NG, Castro M, Rodrigues AS, Gonçalves IC, Martins C, Toscano Rico JM, Rueff J.

Mutat Res. 2005 May 2;583(1):36-48. Epub 2005 Apr 21.

PMID:
15866464
12.

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions.

D'Amours D, Desnoyers S, D'Silva I, Poirier GG.

Biochem J. 1999 Sep 1;342 ( Pt 2):249-68. Review.

13.
14.

Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated.

Saxena A, Saffery R, Wong LH, Kalitsis P, Choo KH.

J Biol Chem. 2002 Jul 26;277(30):26921-6. Epub 2002 May 13.

15.

Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage.

von Kobbe C, Harrigan JA, May A, Opresko PL, Dawut L, Cheng WH, Bohr VA.

Mol Cell Biol. 2003 Dec;23(23):8601-13.

16.

Poly(ADP-ribose) polymerase-1 activation during DNA damage and repair.

Dantzer F, Amé JC, Schreiber V, Nakamura J, Ménissier-de Murcia J, de Murcia G.

Methods Enzymol. 2006;409:493-510.

PMID:
16793420
17.

Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.

Langelier MF, Planck JL, Roy S, Pascal JM.

Science. 2012 May 11;336(6082):728-32. doi: 10.1126/science.1216338.

18.

New polymorphisms in the human poly(ADP-ribose) polymerase-1 coding sequence: lack of association with longevity or with increased cellular poly(ADP-ribosyl)ation capacity.

Cottet F, Blanché H, Verasdonck P, Le Gall I, Schächter F, Bürkle A, Muiras ML.

J Mol Med (Berl). 2000;78(8):431-40.

PMID:
11097112
19.
20.

Photoactivated multivitamin preparation induces poly(ADP-ribosyl)ation, a DNA damage response in mammalian cells.

Zaniolo K, St-Laurent JF, Gagnon SN, Lavoie JC, Desnoyers S.

Free Radic Biol Med. 2010 Apr 15;48(8):1002-12. doi: 10.1016/j.freeradbiomed.2010.01.001. Epub 2010 Jan 25.

PMID:
20100566

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