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Items: 1 to 20 of 121

1.

Perilipin 5, a lipid droplet protein adapted to mitochondrial energy utilization.

Kimmel AR, Sztalryd C.

Curr Opin Lipidol. 2014 Apr;25(2):110-7. doi: 10.1097/MOL.0000000000000057. Review.

2.

Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity.

Bosma M, Sparks LM, Hooiveld GJ, Jorgensen JA, Houten SM, Schrauwen P, Kersten S, Hesselink MK.

Biochim Biophys Acta. 2013 Apr;1831(4):844-52. doi: 10.1016/j.bbalip.2013.01.007. Epub 2013 Jan 22.

PMID:
23353597
3.

Perilipin 5-Driven Lipid Droplet Accumulation in Skeletal Muscle Stimulates the Expression of Fibroblast Growth Factor 21.

Harris LA, Skinner JR, Shew TM, Pietka TA, Abumrad NA, Wolins NE.

Diabetes. 2015 Aug;64(8):2757-68. doi: 10.2337/db14-1035. Epub 2015 Mar 31.

4.

The lipid droplet coat protein perilipin 5 also localizes to muscle mitochondria.

Bosma M, Minnaard R, Sparks LM, Schaart G, Losen M, de Baets MH, Duimel H, Kersten S, Bickel PE, Schrauwen P, Hesselink MK.

Histochem Cell Biol. 2012 Feb;137(2):205-16. doi: 10.1007/s00418-011-0888-x. Epub 2011 Nov 30.

5.

Perilipin 5 is dispensable for normal substrate metabolism and in the adaptation of skeletal muscle to exercise training.

Mohktar RA, Montgomery MK, Murphy RM, Watt MJ.

Am J Physiol Endocrinol Metab. 2016 Jul 1;311(1):E128-37. doi: 10.1152/ajpendo.00084.2016. Epub 2016 May 17.

6.

Changes in mitochondrial perilipin 3 and perilipin 5 protein content in rat skeletal muscle following endurance training and acute stimulated contraction.

Ramos SV, Turnbull PC, MacPherson RE, LeBlanc PJ, Ward WE, Peters SJ.

Exp Physiol. 2015 Apr 1;100(4):450-62. doi: 10.1113/expphysiol.2014.084434. Epub 2015 Mar 21.

7.

The interplay of protein kinase A and perilipin 5 regulates cardiac lipolysis.

Pollak NM, Jaeger D, Kolleritsch S, Zimmermann R, Zechner R, Lass A, Haemmerle G.

J Biol Chem. 2015 Jan 16;290(3):1295-306. doi: 10.1074/jbc.M114.604744. Epub 2014 Nov 22.

8.

Subcellular localization of skeletal muscle lipid droplets and PLIN family proteins OXPAT and ADRP at rest and following contraction in rat soleus muscle.

MacPherson RE, Herbst EA, Reynolds EJ, Vandenboom R, Roy BD, Peters SJ.

Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R29-36. doi: 10.1152/ajpregu.00163.2011. Epub 2011 Oct 19.

9.

Cardiac-specific overexpression of perilipin 5 provokes severe cardiac steatosis via the formation of a lipolytic barrier.

Pollak NM, Schweiger M, Jaeger D, Kolb D, Kumari M, Schreiber R, Kolleritsch S, Markolin P, Grabner GF, Heier C, Zierler KA, Rülicke T, Zimmermann R, Lass A, Zechner R, Haemmerle G.

J Lipid Res. 2013 Apr;54(4):1092-102. doi: 10.1194/jlr.M034710. Epub 2013 Jan 23.

10.

Inactivation of Plin4 downregulates Plin5 and reduces cardiac lipid accumulation in mice.

Chen W, Chang B, Wu X, Li L, Sleeman M, Chan L.

Am J Physiol Endocrinol Metab. 2013 Apr 1;304(7):E770-9. doi: 10.1152/ajpendo.00523.2012. Epub 2013 Feb 19.

11.

Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation.

Kuramoto K, Okamura T, Yamaguchi T, Nakamura TY, Wakabayashi S, Morinaga H, Nomura M, Yanase T, Otsu K, Usuda N, Matsumura S, Inoue K, Fushiki T, Kojima Y, Hashimoto T, Sakai F, Hirose F, Osumi T.

J Biol Chem. 2012 Jul 6;287(28):23852-63. doi: 10.1074/jbc.M111.328708. Epub 2012 Apr 24.

12.

Perilipin 5 restores the formation of lipid droplets in activated hepatic stellate cells and inhibits their activation.

Lin J, Chen A.

Lab Invest. 2016 Jul;96(7):791-806. doi: 10.1038/labinvest.2016.53. Epub 2016 May 2.

13.

Perilipin 5 regulates islet lipid metabolism and insulin secretion in a cAMP-dependent manner: implication of its role in the postprandial insulin secretion.

Trevino MB, Machida Y, Hallinger DR, Garcia E, Christensen A, Dutta S, Peake DA, Ikeda Y, Imai Y.

Diabetes. 2015 Apr;64(4):1299-310. doi: 10.2337/db14-0559. Epub 2014 Nov 12.

14.

Liver Perilipin 5 Expression Worsens Hepatosteatosis But Not Insulin Resistance in High Fat-Fed Mice.

Trevino MB, Mazur-Hart D, Machida Y, King T, Nadler J, Galkina EV, Poddar A, Dutta S, Imai Y.

Mol Endocrinol. 2015 Oct;29(10):1414-25. doi: 10.1210/me.2015-1069. Epub 2015 Aug 21.

15.

Unraveling the roles of PLIN5: linking cell biology to physiology.

Mason RR, Watt MJ.

Trends Endocrinol Metab. 2015 Mar;26(3):144-52. doi: 10.1016/j.tem.2015.01.005. Epub 2015 Feb 11. Review.

PMID:
25682370
16.

Perilipin 5 mediated lipid droplet remodelling revealed by coherent Raman imaging.

Billecke N, Bosma M, Rock W, Fleissner F, Best G, Schrauwen P, Kersten S, Bonn M, Hesselink MK, Parekh SH.

Integr Biol (Camb). 2015 Apr;7(4):467-76. doi: 10.1039/c4ib00271g.

PMID:
25804837
17.

Deficiency of a lipid droplet protein, perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunction.

Kuramoto K, Sakai F, Yoshinori N, Nakamura TY, Wakabayashi S, Kojidani T, Haraguchi T, Hirose F, Osumi T.

Mol Cell Biol. 2014 Jul;34(14):2721-31.

18.

Perilipin-5 is regulated by statins and controls triglyceride contents in the hepatocyte.

Langhi C, Marquart TJ, Allen RM, Baldán A.

J Hepatol. 2014 Aug;61(2):358-65. doi: 10.1016/j.jhep.2014.04.009. Epub 2014 Apr 21.

19.

Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis.

Wang C, Zhao Y, Gao X, Li L, Yuan Y, Liu F, Zhang L, Wu J, Hu P, Zhang X, Gu Y, Xu Y, Wang Z, Li Z, Zhang H, Ye J.

Hepatology. 2015 Mar;61(3):870-82. doi: 10.1002/hep.27409. Epub 2015 Jan 28.

PMID:
25179419
20.

Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction.

Wang H, Sreenivasan U, Gong DW, O'Connell KA, Dabkowski ER, Hecker PA, Ionica N, Konig M, Mahurkar A, Sun Y, Stanley WC, Sztalryd C.

J Lipid Res. 2013 Apr;54(4):953-65. doi: 10.1194/jlr.M032466. Epub 2013 Jan 23.

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