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Items: 1 to 20 of 447

1.

Effects of the HIF-1α and NF-κB loop on epithelial-mesenchymal transition and chemoresistance induced by hypoxia in pancreatic cancer cells.

Cheng ZX, Wang DW, Liu T, Liu WX, Xia WB, Xu J, Zhang YH, Qu YK, Guo LQ, Ding L, Hou J, Zhong ZH.

Oncol Rep. 2014 Apr;31(4):1891-8. doi: 10.3892/or.2014.3022. Epub 2014 Feb 11.

PMID:
24535079
2.

Nuclear factor-κB-dependent epithelial to mesenchymal transition induced by HIF-1α activation in pancreatic cancer cells under hypoxic conditions.

Cheng ZX, Sun B, Wang SJ, Gao Y, Zhang YM, Zhou HX, Jia G, Wang YW, Kong R, Pan SH, Xue DB, Jiang HC, Bai XW.

PLoS One. 2011;6(8):e23752. doi: 10.1371/journal.pone.0023752. Epub 2011 Aug 22.

4.

[Experimental study of the function of nuclear factor-κB-dependent epithelial to mesenchymal transition in pancreatic cancer cells under hypoxic conditions].

Cheng ZX, Sun B, Wang SJ, Zhou HX, Jia G, Kong R, Wang G, Jiang HC.

Zhonghua Wai Ke Za Zhi. 2012 May;50(5):446-51. Chinese.

PMID:
22883954
5.

Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells.

Shimojo Y, Akimoto M, Hisanaga T, Tanaka T, Tajima Y, Honma Y, Takenaga K.

Clin Exp Metastasis. 2013 Feb;30(2):143-54. doi: 10.1007/s10585-012-9519-8. Epub 2012 Jul 26.

PMID:
22833345
6.

Nuclear factor-κB2/p100 promotes endometrial carcinoma cell survival under hypoxia in a HIF-1α independent manner.

Yeramian A, Santacana M, Sorolla A, Llobet D, Encinas M, Velasco A, Bahi N, Eritja N, Domingo M, Oliva E, Dolcet X, Matias-Guiu X.

Lab Invest. 2011 Jun;91(6):859-71. doi: 10.1038/labinvest.2011.58. Epub 2011 May 2.

7.

Upregulation of autophagy by hypoxia-inducible factor-1α promotes EMT and metastatic ability of CD133+ pancreatic cancer stem-like cells during intermittent hypoxia.

Zhu H, Wang D, Zhang L, Xie X, Wu Y, Liu Y, Shao G, Su Z.

Oncol Rep. 2014 Sep;32(3):935-42. doi: 10.3892/or.2014.3298. Epub 2014 Jul 2.

PMID:
24994549
8.

Wnt/β-catenin signaling enhances hypoxia-induced epithelial-mesenchymal transition in hepatocellular carcinoma via crosstalk with hif-1α signaling.

Zhang Q, Bai X, Chen W, Ma T, Hu Q, Liang C, Xie S, Chen C, Hu L, Xu S, Liang T.

Carcinogenesis. 2013 May;34(5):962-73. doi: 10.1093/carcin/bgt027. Epub 2013 Jan 27.

PMID:
23358852
9.

Inflammatory stimulation and hypoxia cooperatively activate HIF-1{alpha} in bronchial epithelial cells: involvement of PI3K and NF-{kappa}B.

Jiang H, Zhu YS, Xu H, Sun Y, Li QF.

Am J Physiol Lung Cell Mol Physiol. 2010 May;298(5):L660-9. doi: 10.1152/ajplung.00394.2009. Epub 2010 Feb 5.

10.

Interleukin-17A promotes rheumatoid arthritis synoviocytes migration and invasion under hypoxia by increasing MMP2 and MMP9 expression through NF-κB/HIF-1α pathway.

Li G, Zhang Y, Qian Y, Zhang H, Guo S, Sunagawa M, Hisamitsu T, Liu Y.

Mol Immunol. 2013 Mar;53(3):227-36. doi: 10.1016/j.molimm.2012.08.018. Epub 2012 Sep 5.

PMID:
22960198
11.

Hypoxia-inducible factor-1alpha induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition.

Sun S, Ning X, Zhang Y, Lu Y, Nie Y, Han S, Liu L, Du R, Xia L, He L, Fan D.

Kidney Int. 2009 Jun;75(12):1278-87. doi: 10.1038/ki.2009.62. Epub 2009 Mar 11.

12.

YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.

Sun HL, Liu YN, Huang YT, Pan SL, Huang DY, Guh JH, Lee FY, Kuo SC, Teng CM.

Oncogene. 2007 Jun 7;26(27):3941-51. Epub 2007 Jan 8.

PMID:
17213816
13.

Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1alpha.

Huang L, Ao Q, Zhang Q, Yang X, Xing H, Li F, Chen G, Zhou J, Wang S, Xu G, Meng L, Lu Y, Ma D.

J Cancer Res Clin Oncol. 2010 Mar;136(3):447-56. doi: 10.1007/s00432-009-0675-4. Epub 2009 Sep 16.

PMID:
19760195
14.

Tanshinone IIA blocks epithelial-mesenchymal transition through HIF-1α downregulation, reversing hypoxia-induced chemotherapy resistance in breast cancer cell lines.

Fu P, Du F, Chen W, Yao M, Lv K, Liu Y.

Oncol Rep. 2014 Jun;31(6):2561-8. doi: 10.3892/or.2014.3140. Epub 2014 Apr 16.

PMID:
24737252
15.

Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner.

Lei J, Ma J, Ma Q, Li X, Liu H, Xu Q, Duan W, Sun Q, Xu J, Wu Z, Wu E.

Mol Cancer. 2013 Jun 20;12:66. doi: 10.1186/1476-4598-12-66.

16.

Hypoxia Induces Epithelial-Mesenchymal Transition in Follicular Thyroid Cancer: Involvement of Regulation of Twist by Hypoxia Inducible Factor-1α.

Yang YJ, Na HJ, Suh MJ, Ban MJ, Byeon HK, Kim WS, Kim JW, Choi EC, Kwon HJ, Chang JW, Koh YW.

Yonsei Med J. 2015 Nov;56(6):1503-14. doi: 10.3349/ymj.2015.56.6.1503.

17.

CD133 Modulate HIF-1α Expression under Hypoxia in EMT Phenotype Pancreatic Cancer Stem-Like Cells.

Maeda K, Ding Q, Yoshimitsu M, Kuwahata T, Miyazaki Y, Tsukasa K, Hayashi T, Shinchi H, Natsugoe S, Takao S.

Int J Mol Sci. 2016 Jun 28;17(7). pii: E1025. doi: 10.3390/ijms17071025.

18.

Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway.

Wang Z, Li Y, Kong D, Banerjee S, Ahmad A, Azmi AS, Ali S, Abbruzzese JL, Gallick GE, Sarkar FH.

Cancer Res. 2009 Mar 15;69(6):2400-7. doi: 10.1158/0008-5472.CAN-08-4312. Epub 2009 Mar 10.

19.
20.

Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB.

Rohwer N, Dame C, Haugstetter A, Wiedenmann B, Detjen K, Schmitt CA, Cramer T.

PLoS One. 2010 Aug 10;5(8):e12038. doi: 10.1371/journal.pone.0012038.

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