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Items: 1 to 20 of 426

1.

Resveratrol prevents TNF-α-induced muscle atrophy via regulation of Akt/mTOR/FoxO1 signaling in C2C12 myotubes.

Wang DT, Yin Y, Yang YJ, Lv PJ, Shi Y, Lu L, Wei LB.

Int Immunopharmacol. 2014 Apr;19(2):206-13. doi: 10.1016/j.intimp.2014.02.002. Epub 2014 Feb 15.

PMID:
24534773
2.

Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy.

Léger B, Cartoni R, Praz M, Lamon S, Dériaz O, Crettenand A, Gobelet C, Rohmer P, Konzelmann M, Luthi F, Russell AP.

J Physiol. 2006 Nov 1;576(Pt 3):923-33. Epub 2006 Aug 17.

3.

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.

Stitt TN, Drujan D, Clarke BA, Panaro F, Timofeyva Y, Kline WO, Gonzalez M, Yancopoulos GD, Glass DJ.

Mol Cell. 2004 May 7;14(3):395-403.

4.

β-Hydroxy-β-methylbutyrate facilitates PI3K/Akt-dependent mammalian target of rapamycin and FoxO1/3a phosphorylations and alleviates tumor necrosis factor α/interferon γ-induced MuRF-1 expression in C2C12 cells.

Kimura K, Cheng XW, Inoue A, Hu L, Koike T, Kuzuya M.

Nutr Res. 2014 Apr;34(4):368-74. doi: 10.1016/j.nutres.2014.02.003. Epub 2014 Feb 10.

PMID:
24774073
5.

Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats.

Sheriff S, Kadeer N, Joshi R, Friend LA, James JH, Balasubramaniam A.

Mol Cell Endocrinol. 2012 Apr 4;351(2):286-95. doi: 10.1016/j.mce.2011.12.021. Epub 2012 Jan 14.

PMID:
22266196
6.
7.

Iron-induced skeletal muscle atrophy involves an Akt-forkhead box O3-E3 ubiquitin ligase-dependent pathway.

Ikeda Y, Imao M, Satoh A, Watanabe H, Hamano H, Horinouchi Y, Izawa-Ishizawa Y, Kihira Y, Miyamoto L, Ishizawa K, Tsuchiya K, Tamaki T.

J Trace Elem Med Biol. 2016 May;35:66-76. doi: 10.1016/j.jtemb.2016.01.011. Epub 2016 Jan 28.

PMID:
27049128
8.

TNF induction of atrogin-1/MAFbx mRNA depends on Foxo4 expression but not AKT-Foxo1/3 signaling.

Moylan JS, Smith JD, Chambers MA, McLoughlin TJ, Reid MB.

Am J Physiol Cell Physiol. 2008 Oct;295(4):C986-93. doi: 10.1152/ajpcell.00041.2008. Epub 2008 Aug 13.

9.

Suppression of atrogin-1 and MuRF1 prevents dexamethasone-induced atrophy of cultured myotubes.

Castillero E, Alamdari N, Lecker SH, Hasselgren PO.

Metabolism. 2013 Oct;62(10):1495-502. doi: 10.1016/j.metabol.2013.05.018. Epub 2013 Jul 15.

PMID:
23866982
10.

Isoflavones derived from soy beans prevent MuRF1-mediated muscle atrophy in C2C12 myotubes through SIRT1 activation.

Hirasaka K, Maeda T, Ikeda C, Haruna M, Kohno S, Abe T, Ochi A, Mukai R, Oarada M, Eshima-Kondo S, Ohno A, Okumura Y, Terao J, Nikawa T.

J Nutr Sci Vitaminol (Tokyo). 2013;59(4):317-24.

11.

C/EBPβ mediates tumour-induced ubiquitin ligase atrogin1/MAFbx upregulation and muscle wasting.

Zhang G, Jin B, Li YP.

EMBO J. 2011 Aug 16;30(20):4323-35. doi: 10.1038/emboj.2011.292.

12.

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size.

Trendelenburg AU, Meyer A, Rohner D, Boyle J, Hatakeyama S, Glass DJ.

Am J Physiol Cell Physiol. 2009 Jun;296(6):C1258-70. doi: 10.1152/ajpcell.00105.2009. Epub 2009 Apr 8.

13.

mTORC1 promotes denervation-induced muscle atrophy through a mechanism involving the activation of FoxO and E3 ubiquitin ligases.

Tang H, Inoki K, Lee M, Wright E, Khuong A, Khuong A, Sugiarto S, Garner M, Paik J, DePinho RA, Goldman D, Guan KL, Shrager JB.

Sci Signal. 2014 Feb 25;7(314):ra18. doi: 10.1126/scisignal.2004809.

PMID:
24570486
14.

Muscle-specific E3 ubiquitin ligases are involved in muscle atrophy of cancer cachexia: an in vitro and in vivo study.

Yuan L, Han J, Meng Q, Xi Q, Zhuang Q, Jiang Y, Han Y, Zhang B, Fang J, Wu G.

Oncol Rep. 2015 May;33(5):2261-8. doi: 10.3892/or.2015.3845. Epub 2015 Mar 9.

PMID:
25760630
15.

Sepsis increases the expression and activity of the transcription factor Forkhead Box O 1 (FOXO1) in skeletal muscle by a glucocorticoid-dependent mechanism.

Smith IJ, Alamdari N, O'Neal P, Gonnella P, Aversa Z, Hasselgren PO.

Int J Biochem Cell Biol. 2010 May;42(5):701-11. doi: 10.1016/j.biocel.2010.01.006. Epub 2010 Jan 13.

16.

Involvement of the FoxO1/MuRF1/Atrogin-1 Signaling Pathway in the Oxidative Stress-Induced Atrophy of Cultured Chronic Obstructive Pulmonary Disease Myotubes.

Pomiès P, Blaquière M, Maury J, Mercier J, Gouzi F, Hayot M.

PLoS One. 2016 Aug 15;11(8):e0160092. doi: 10.1371/journal.pone.0160092. eCollection 2016.

17.

TRAF6 inhibition rescues dexamethasone-induced muscle atrophy.

Sun H, Gong Y, Qiu J, Chen Y, Ding F, Zhao Q.

Int J Mol Sci. 2014 Jun 20;15(6):11126-41. doi: 10.3390/ijms150611126.

18.

Atrogin-1, MuRF1, and FoXO, as well as phosphorylated GSK-3beta and 4E-BP1 are reduced in skeletal muscle of chronic spinal cord-injured patients.

Léger B, Senese R, Al-Khodairy AW, Dériaz O, Gobelet C, Giacobino JP, Russell AP.

Muscle Nerve. 2009 Jul;40(1):69-78. doi: 10.1002/mus.21293.

PMID:
19533653
19.

Angiotensin-(1-7) decreases skeletal muscle atrophy induced by angiotensin II through a Mas receptor-dependent mechanism.

Cisternas F, Morales MG, Meneses C, Simon F, Brandan E, Abrigo J, Vazquez Y, Cabello-Verrugio C.

Clin Sci (Lond). 2015 Mar;128(5):307-19. doi: 10.1042/CS20140215.

PMID:
25222828
20.

Resveratrol prevents dexamethasone-induced expression of the muscle atrophy-related ubiquitin ligases atrogin-1 and MuRF1 in cultured myotubes through a SIRT1-dependent mechanism.

Alamdari N, Aversa Z, Castillero E, Gurav A, Petkova V, Tizio S, Hasselgren PO.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):528-33. doi: 10.1016/j.bbrc.2011.11.154. Epub 2011 Dec 7.

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