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Items: 1 to 20 of 76

1.

Synthesis of PPAR-γ activators inspired by the marine natural product, paecilocin A.

Xiao B, Su M, Kim EL, Hong J, Chung HY, Kim HS, Yin J, Jung JH.

Mar Drugs. 2014 Feb 13;12(2):926-39. doi: 10.3390/md12020926.

2.

Synthesis of Phthalimide Derivatives as Potential PPAR-γ Ligands.

Eom SH, Liu S, Su M, Noh TH, Hong J, Kim ND, Chung HY, Yang MH, Jung JH.

Mar Drugs. 2016 Jun 8;14(6). pii: E112. doi: 10.3390/md14060112.

3.

Design and synthesis of marine fungal phthalide derivatives as PPAR-γ agonists.

Xiao B, Yin J, Park M, Liu J, Li JL, Kim EL, Hong J, Chung HY, Jung JH.

Bioorg Med Chem. 2012 Aug 15;20(16):4954-61. doi: 10.1016/j.bmc.2012.06.039. Epub 2012 Jun 29.

PMID:
22819190
4.

Novel PPAR-gamma agonists identified from a natural product library: a virtual screening, induced-fit docking and biological assay study.

Salam NK, Huang TH, Kota BP, Kim MS, Li Y, Hibbs DE.

Chem Biol Drug Des. 2008 Jan;71(1):57-70. Epub 2007 Dec 18.

PMID:
18086153
5.

Thiazolidine-2,4-diones derivatives as PPAR-γ agonists: synthesis, molecular docking, in vitro and in vivo antidiabetic activity with hepatotoxicity risk evaluation and effect on PPAR-γ gene expression.

Nazreen S, Alam MS, Hamid H, Yar MS, Dhulap A, Alam P, Pasha MA, Bano S, Alam MM, Haider S, Kharbanda C, Ali Y, Pillai KK.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3034-42. doi: 10.1016/j.bmcl.2014.05.034. Epub 2014 May 22.

PMID:
24890090
6.

Phthalides and phthalans: synthetic methodologies and their applications in the total synthesis.

Karmakar R, Pahari P, Mal D.

Chem Rev. 2014 Jun 25;114(12):6213-84. doi: 10.1021/cr400524q. Epub 2014 May 13. Review. No abstract available.

PMID:
24823231
7.

[Effect of peroxisome proliferators activated receptor gamma and its ligand on airway mucus hypersecretion in rats].

Liu WJ, Li WC, Xu ZB, Feng YL.

Zhonghua Jie He He Hu Xi Za Zhi. 2009 Apr;32(4):282-6. Chinese.

PMID:
19576043
8.

A stereo-controlled synthesis of 2,4-dimethyl-4-hydroxy-16-phenylhexadecanoic acid 1,4-lactone and its PPAR activities.

Ko J, Hwang H, Chin J, Hahn D, Lee J, Yang I, Shin K, Ham J, Kang H.

Bioorg Med Chem Lett. 2010 Oct 15;20(20):6017-9. doi: 10.1016/j.bmcl.2010.08.069. Epub 2010 Aug 19.

PMID:
20822906
9.

Rosiglitazone, PPAR-gamma receptor ligand, decreases the viability of rat prolactin-secreting pituitary tumor cells in vitro.

Gruszka A, Kunert-Radek J, Pawlikowski M.

Neuro Endocrinol Lett. 2005 Feb;26(1):51-4.

PMID:
15726020
10.

Agonists at PPAR-gamma suppress angiotensin II-induced production of plasminogen activator inhibitor-1 and extracellular matrix in rat cardiac fibroblasts.

Hao GH, Niu XL, Gao DF, Wei J, Wang NP.

Br J Pharmacol. 2008 Apr;153(7):1409-19. doi: 10.1038/bjp.2008.21. Epub 2008 Feb 18.

11.

Human scavenger receptor class B type 1 is regulated by activators of peroxisome proliferators-activated receptor-gamma in hepatocytes.

Ahmed RA, Murao K, Imachi H, Yu X, Li J, Wong NC, Ishida T.

Endocrine. 2009 Apr;35(2):233-42. doi: 10.1007/s12020-008-9142-2. Epub 2009 Jan 21.

PMID:
19156545
12.

PPAR-γ activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic β-cells.

Kim HS, Hwang YC, Koo SH, Park KS, Lee MS, Kim KW, Lee MK.

PLoS One. 2013;8(1):e50128. doi: 10.1371/journal.pone.0050128. Epub 2013 Jan 23.

13.
14.

Activated AMPK inhibits PPAR-{alpha} and PPAR-{gamma} transcriptional activity in hepatoma cells.

Sozio MS, Lu C, Zeng Y, Liangpunsakul S, Crabb DW.

Am J Physiol Gastrointest Liver Physiol. 2011 Oct;301(4):G739-47. doi: 10.1152/ajpgi.00161.2011. Epub 2011 Jun 23.

15.

PPAR-γ agonistic metabolites from the ascidian Herdmania momus.

Li JL, Xiao B, Park M, Yoo ES, Shin S, Hong J, Chung HY, Kim HS, Jung JH.

J Nat Prod. 2012 Dec 28;75(12):2082-7. doi: 10.1021/np300401g. Epub 2012 Nov 28. Erratum in: J Nat Prod. 2013 Apr 26;76(4):815.

PMID:
23189988
16.

Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion.

Park JB, Kim BK, Kwon YW, Muller DN, Lee HC, Youn SW, Choi YE, Lee SW, Yang HM, Cho HJ, Park KW, Kim HS.

PLoS One. 2011;6(11):e28327. doi: 10.1371/journal.pone.0028327. Epub 2011 Nov 29.

17.

Design, synthesis, and biological activity of novel PPARgamma ligands based on rosiglitazone and 15d-PGJ2.

Usui S, Suzuki T, Hattori Y, Etoh K, Fujieda H, Nishizuka M, Imagawa M, Nakagawa H, Kohda K, Miyata N.

Bioorg Med Chem Lett. 2005 Mar 15;15(6):1547-51.

PMID:
15745794
18.

Antidiabetic and hypolipidemic potential of DRF 2519--a dual activator of PPAR-alpha and PPAR-gamma.

Chakrabarti R, Misra P, Vikramadithyan RK, Premkumar M, Hiriyan J, Datla SR, Damarla RK, Suresh J, Rajagopalan R.

Eur J Pharmacol. 2004 May 3;491(2-3):195-206.

PMID:
15140637
19.

Effects of peroxisome proliferator-activated receptors-gamma ligands on dextran sodium sulphate-induced colitis in rats.

Celinski K, Dworzanski T, Korolczuk A, Piasecki R, Slomka M, Madro A, Fornal R.

J Physiol Pharmacol. 2011 Jun;62(3):347-56.

20.

Ligands for the peroxisome proliferator-activated receptor-gamma have inhibitory effects on growth of human neuroblastoma cells in vitro.

Valentiner U, Carlsson M, Erttmann R, Hildebrandt H, Schumacher U.

Toxicology. 2005 Sep 15;213(1-2):157-68.

PMID:
16009482

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