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Items: 1 to 20 of 144

1.

Hypoxia and STAT3 signalling interactions regulate pro-inflammatory pathways in rheumatoid arthritis.

Gao W, McCormick J, Connolly M, Balogh E, Veale DJ, Fearon U.

Ann Rheum Dis. 2015 Jun;74(6):1275-83. doi: 10.1136/annrheumdis-2013-204105.

PMID:
24525913
2.

Notch-1 mediates hypoxia-induced angiogenesis in rheumatoid arthritis.

Gao W, Sweeney C, Connolly M, Kennedy A, Ng CT, McCormick J, Veale DJ, Fearon U.

Arthritis Rheum. 2012 Jul;64(7):2104-13. doi: 10.1002/art.34397.

3.

Toll-like receptor 2 (TLR2) induces migration and invasive mechanisms in rheumatoid arthritis.

McGarry T, Veale DJ, Gao W, Orr C, Fearon U, Connolly M.

Arthritis Res Ther. 2015 Jun 9;17:153. doi: 10.1186/s13075-015-0664-8.

4.

Notch signalling pathways mediate synovial angiogenesis in response to vascular endothelial growth factor and angiopoietin 2.

Gao W, Sweeney C, Walsh C, Rooney P, McCormick J, Veale DJ, Fearon U.

Ann Rheum Dis. 2013 Jun;72(6):1080-8. doi: 10.1136/annrheumdis-2012-201978.

5.

Interleukin-17 increases the expression of Toll-like receptor 3 via the STAT3 pathway in rheumatoid arthritis fibroblast-like synoviocytes.

Lee SY, Yoon BY, Kim JI, Heo YM, Woo YJ, Park SH, Kim HY, Kim SI, Cho ML.

Immunology. 2014 Mar;141(3):353-61. doi: 10.1111/imm.12196.

6.
7.

Hypoxia differentially affects IL-1β-stimulated MMP-1 and MMP-13 expression of fibroblast-like synoviocytes in an HIF-1α-dependent manner.

Lee YA, Choi HM, Lee SH, Hong SJ, Yang HI, Yoo MC, Kim KS.

Rheumatology (Oxford). 2012 Mar;51(3):443-50. doi: 10.1093/rheumatology/ker327.

8.

Interleukin-21 induces migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis.

Xing R, Jin Y, Sun L, Yang L, Li C, Li Z, Liu X, Zhao J.

Clin Exp Immunol. 2016 May;184(2):147-58. doi: 10.1111/cei.12751.

PMID:
26646950
9.

Role of hypoxia-inducible factor-1alpha in hypoxia-induced expressions of IL-8, MMP-1 and MMP-3 in rheumatoid fibroblast-like synoviocytes.

Ahn JK, Koh EM, Cha HS, Lee YS, Kim J, Bae EK, Ahn KS.

Rheumatology (Oxford). 2008 Jun;47(6):834-9. doi: 10.1093/rheumatology/ken086.

10.

Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways.

Filer A, Bik M, Parsonage GN, Fitton J, Trebilcock E, Howlett K, Cook M, Raza K, Simmons DL, Thomas AM, Salmon M, Scheel-Toellner D, Lord JM, Rabinovich GA, Buckley CD.

Arthritis Rheum. 2009 Jun;60(6):1604-14. doi: 10.1002/art.24574.

11.

Resveratrol inhibits TNF-α-induced IL-1β, MMP-3 production in human rheumatoid arthritis fibroblast-like synoviocytes via modulation of PI3kinase/Akt pathway.

Tian J, Chen JW, Gao JS, Li L, Xie X.

Rheumatol Int. 2013 Jul;33(7):1829-35. doi: 10.1007/s00296-012-2657-0.

PMID:
23328930
12.

Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures.

Ultaigh SN, Saber TP, McCormick J, Connolly M, Dellacasagrande J, Keogh B, McCormack W, Reilly M, O'Neill LA, McGuirk P, Fearon U, Veale DJ.

Arthritis Res Ther. 2011 Feb 23;13(1):R33. doi: 10.1186/ar3261.

13.

Interleukin-29 modulates proinflammatory cytokine production in synovial inflammation of rheumatoid arthritis.

Wang F, Xu L, Feng X, Guo D, Tan W, Zhang M.

Arthritis Res Ther. 2012 Oct 19;14(5):R228. doi: 10.1186/ar4067.

14.

Leptin stimulates interleukin-6 production via janus kinase 2/signal transducer and activator of transcription 3 in rheumatoid synovial fibroblasts.

Muraoka S, Kusunoki N, Takahashi H, Tsuchiya K, Kawai S.

Clin Exp Rheumatol. 2013 Jul-Aug;31(4):589-95.

PMID:
23622344
15.

IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17.

Hashizume M, Hayakawa N, Mihara M.

Rheumatology (Oxford). 2008 Nov;47(11):1635-40. doi: 10.1093/rheumatology/ken363.

16.

The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts.

Klein K, Kabala PA, Grabiec AM, Gay RE, Kolling C, Lin LL, Gay S, Tak PP, Prinjha RK, Ospelt C, Reedquist KA.

Ann Rheum Dis. 2016 Feb;75(2):422-9. doi: 10.1136/annrheumdis-2014-205809.

PMID:
25467295
17.

Tofacitinib regulates synovial inflammation in psoriatic arthritis, inhibiting STAT activation and induction of negative feedback inhibitors.

Gao W, McGarry T, Orr C, McCormick J, Veale DJ, Fearon U.

Ann Rheum Dis. 2016 Jan;75(1):311-5. doi: 10.1136/annrheumdis-2014-207201.

18.

Hypoxia and hypoxia-inducible factor-1α provoke toll-like receptor signalling-induced inflammation in rheumatoid arthritis.

Hu F, Mu R, Zhu J, Shi L, Li Y, Liu X, Shao W, Li G, Li M, Su Y, Cohen PL, Qiu X, Li Z.

Ann Rheum Dis. 2014 May;73(5):928-36. doi: 10.1136/annrheumdis-2012-202444.

PMID:
23644550
19.

The anti-malaria agent artesunate inhibits expression of vascular endothelial growth factor and hypoxia-inducible factor-1α in human rheumatoid arthritis fibroblast-like synoviocyte.

He Y, Fan J, Lin H, Yang X, Ye Y, Liang L, Zhan Z, Dong X, Sun L, Xu H.

Rheumatol Int. 2011 Jan;31(1):53-60. doi: 10.1007/s00296-009-1218-7.

PMID:
19859713
20.
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