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Items: 1 to 20 of 282

1.

Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice.

Chopra P, Papale LA, White AT, Hatch A, Brown RM, Garthwaite MA, Roseboom PH, Golos TG, Warren ST, Alisch RS.

BMC Genomics. 2014 Feb 13;15:131. doi: 10.1186/1471-2164-15-131.

2.

Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain.

Wen L, Li X, Yan L, Tan Y, Li R, Zhao Y, Wang Y, Xie J, Zhang Y, Song C, Yu M, Liu X, Zhu P, Li X, Hou Y, Guo H, Wu X, He C, Li R, Tang F, Qiao J.

Genome Biol. 2014 Mar 4;15(3):R49. doi: 10.1186/gb-2014-15-3-r49.

3.

Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G, Chandran S, Hay DC, Bradley M, Wilmut I, De Sousa P.

Cell Res. 2011 Sep;21(9):1332-42. doi: 10.1038/cr.2011.113. Epub 2011 Jul 12.

4.

High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.

Davis T, Vaisvila R.

J Vis Exp. 2011 Feb 1;(48). pii: 2661. doi: 10.3791/2661.

5.

5-hydroxymethylcytosine: a new insight into epigenetics in cancer.

Ye C, Li L.

Cancer Biol Ther. 2014 Jan;15(1):10-5. doi: 10.4161/cbt.27144. Epub 2013 Nov 19. Review.

6.

5-methylcytosine and its derivatives.

Yuan BF.

Adv Clin Chem. 2014;67:151-87. doi: 10.1016/bs.acc.2014.09.003. Epub 2014 Nov 4. Review.

PMID:
25735861
7.
8.

Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry.

Chen ML, Shen F, Huang W, Qi JH, Wang Y, Feng YQ, Liu SM, Yuan BF.

Clin Chem. 2013 May;59(5):824-32. doi: 10.1373/clinchem.2012.193938. Epub 2013 Jan 23.

9.

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

Bhattacharyya S, Yu Y, Suzuki M, Campbell N, Mazdo J, Vasanthakumar A, Bhagat TD, Nischal S, Christopeit M, Parekh S, Steidl U, Godley L, Maitra A, Greally JM, Verma A.

Nucleic Acids Res. 2013 Sep;41(16):e157. doi: 10.1093/nar/gkt601. Epub 2013 Jul 16.

10.

CpG site-specific alteration of hydroxymethylcytosine to methylcytosine beyond DNA replication.

Kubosaki A, Tomaru Y, Furuhata E, Suzuki T, Shin JW, Simon C, Ando Y, Hasegawa R, Hayashizaki Y, Suzuki H.

Biochem Biophys Res Commun. 2012 Sep 14;426(1):141-7. doi: 10.1016/j.bbrc.2012.08.053. Epub 2012 Aug 17.

11.

Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.

Song CX, He C.

Acc Chem Res. 2011 Sep 20;44(9):709-17. doi: 10.1021/ar2000502. Epub 2011 May 3.

12.

Studying the epigenome using next generation sequencing.

Ku CS, Naidoo N, Wu M, Soong R.

J Med Genet. 2011 Nov;48(11):721-30. doi: 10.1136/jmedgenet-2011-100242. Epub 2011 Aug 8. Review.

PMID:
21825079
14.

DNA binding of the p21 repressor ZBTB2 is inhibited by cytosine hydroxymethylation.

Lafaye C, Barbier E, Miscioscia A, Saint-Pierre C, Kraut A, Couté Y, Plo I, Gasparutto D, Ravanat JL, Breton J.

Biochem Biophys Res Commun. 2014 Mar 28;446(1):341-6. doi: 10.1016/j.bbrc.2014.02.122. Epub 2014 Mar 4.

PMID:
24607898
15.

MLML: consistent simultaneous estimates of DNA methylation and hydroxymethylation.

Qu J, Zhou M, Song Q, Hong EE, Smith AD.

Bioinformatics. 2013 Oct 15;29(20):2645-6. doi: 10.1093/bioinformatics/btt459. Epub 2013 Aug 21.

16.

5-Hydroxymethylcytosine, the sixth base of the genome.

Münzel M, Globisch D, Carell T.

Angew Chem Int Ed Engl. 2011 Jul 11;50(29):6460-8. doi: 10.1002/anie.201101547. Epub 2011 Jun 17. Review.

PMID:
21688365
17.

Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease.

Wang F, Yang Y, Lin X, Wang JQ, Wu YS, Xie W, Wang D, Zhu S, Liao YQ, Sun Q, Yang YG, Luo HR, Guo C, Han C, Tang TS.

Hum Mol Genet. 2013 Sep 15;22(18):3641-53. doi: 10.1093/hmg/ddt214. Epub 2013 May 12.

PMID:
23669348
18.

Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.

Minor EA, Court BL, Young JI, Wang G.

J Biol Chem. 2013 May 10;288(19):13669-74. doi: 10.1074/jbc.C113.464800. Epub 2013 Apr 2.

19.

Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues.

Wagner M, Steinbacher J, Kraus TF, Michalakis S, Hackner B, Pfaffeneder T, Perera A, Müller M, Giese A, Kretzschmar HA, Carell T.

Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12511-4. doi: 10.1002/anie.201502722. Epub 2015 Jul 3.

20.

Integrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation.

Gao F, Xia Y, Wang J, Luo H, Gao Z, Han X, Zhang J, Huang X, Yao Y, Lu H, Yi N, Zhou B, Lin Z, Wen B, Zhang X, Yang H, Wang J.

Epigenetics. 2013 Apr;8(4):421-30. doi: 10.4161/epi.24280. Epub 2013 Mar 15.

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