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Items: 1 to 20 of 88

1.

Brain imaging of cognitively normal individuals with 2 parents affected by late-onset AD.

Mosconi L, Murray J, Tsui WH, Li Y, Spector N, Goldowsky A, Williams S, Osorio R, McHugh P, Glodzik L, Vallabhajosula S, de Leon MJ.

Neurology. 2014 Mar 4;82(9):752-60. doi: 10.1212/WNL.0000000000000181. Epub 2014 Feb 12.

2.

Increased fibrillar amyloid-{beta} burden in normal individuals with a family history of late-onset Alzheimer's.

Mosconi L, Rinne JO, Tsui WH, Berti V, Li Y, Wang H, Murray J, Scheinin N, Någren K, Williams S, Glodzik L, De Santi S, Vallabhajosula S, de Leon MJ.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5949-54. doi: 10.1073/pnas.0914141107. Epub 2010 Mar 15.

3.

Structural brain changes in normal individuals with a maternal history of Alzheimer's.

Berti V, Mosconi L, Glodzik L, Li Y, Murray J, De Santi S, Pupi A, Tsui W, De Leon MJ.

Neurobiol Aging. 2011 Dec;32(12):2325.e17-26. doi: 10.1016/j.neurobiolaging.2011.01.001. Epub 2011 Feb 12.

4.

FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer's Disease.

Murray J, Tsui WH, Li Y, McHugh P, Williams S, Cummings M, Pirraglia E, Solnes L, Osorio R, Glodzik L, Vallabhajosula S, Drzezga A, Minoshima S, de Leon MJ, Mosconi L.

Adv J Mol Imaging. 2014 Apr;4(2):15-26.

5.

Progressive regional atrophy in normal adults with a maternal history of Alzheimer disease.

Honea RA, Swerdlow RH, Vidoni ED, Burns JM.

Neurology. 2011 Mar 1;76(9):822-9. doi: 10.1212/WNL.0b013e31820e7b74.

6.

Reduced gray matter volume in normal adults with a maternal family history of Alzheimer disease.

Honea RA, Swerdlow RH, Vidoni ED, Goodwin J, Burns JM.

Neurology. 2010 Jan 12;74(2):113-20. doi: 10.1212/WNL.0b013e3181c918cb.

7.

Comparing brain amyloid deposition, glucose metabolism, and atrophy in mild cognitive impairment with and without a family history of dementia.

Mosconi L, Andrews RD, Matthews DC.

J Alzheimers Dis. 2013;35(3):509-24. doi: 10.3233/JAD-121867.

PMID:
23478305
8.

Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease.

Mosconi L, Mistur R, Switalski R, Brys M, Glodzik L, Rich K, Pirraglia E, Tsui W, De Santi S, de Leon MJ.

Neurology. 2009 Feb 10;72(6):513-20. doi: 10.1212/01.wnl.0000333247.51383.43. Epub 2008 Nov 12.

9.

Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parents.

Mosconi L, Rinne JO, Tsui WH, Murray J, Li Y, Glodzik L, McHugh P, Williams S, Cummings M, Pirraglia E, Goldsmith SJ, Vallabhajosula S, Scheinin N, Viljanen T, Någren K, de Leon MJ.

Neurobiol Aging. 2013 Jan;34(1):22-34. doi: 10.1016/j.neurobiolaging.2012.03.002. Epub 2012 Apr 11.

10.

Nutrient patterns and brain biomarkers of Alzheimer's disease in cognitively normal individuals.

Berti V, Murray J, Davies M, Spector N, Tsui WH, Li Y, Williams S, Pirraglia E, Vallabhajosula S, McHugh P, Pupi A, de Leon MJ, Mosconi L.

J Nutr Health Aging. 2015 Apr;19(4):413-23. doi: 10.1007/s12603-014-0534-0.

11.

Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism.

Mosconi L, Brys M, Switalski R, Mistur R, Glodzik L, Pirraglia E, Tsui W, De Santi S, de Leon MJ.

Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19067-72. Epub 2007 Nov 14.

12.

11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment.

Jack CR Jr, Lowe VJ, Senjem ML, Weigand SD, Kemp BJ, Shiung MM, Knopman DS, Boeve BF, Klunk WE, Mathis CA, Petersen RC.

Brain. 2008 Mar;131(Pt 3):665-80. doi: 10.1093/brain/awm336. Epub 2008 Feb 7.

13.

Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease.

Drzezga A, Grimmer T, Henriksen G, Mühlau M, Perneczky R, Miederer I, Praus C, Sorg C, Wohlschläger A, Riemenschneider M, Wester HJ, Foerstl H, Schwaiger M, Kurz A.

Neurology. 2009 Apr 28;72(17):1487-94. doi: 10.1212/WNL.0b013e3181a2e8d0. Epub 2009 Apr 1.

PMID:
19339712
14.

Prefrontal hypometabolism in Alzheimer disease is related to longitudinal amyloid accumulation in remote brain regions.

Klupp E, Grimmer T, Tahmasian M, Sorg C, Yakushev I, Yousefi BH, Drzezga A, Förster S.

J Nucl Med. 2015 Mar;56(3):399-404. doi: 10.2967/jnumed.114.149302. Epub 2015 Feb 12.

15.

Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation.

Roberts RO, Knopman DS, Cha RH, Mielke MM, Pankratz VS, Boeve BF, Kantarci K, Geda YE, Jack CR Jr, Petersen RC, Lowe VJ.

J Nucl Med. 2014 May;55(5):759-64. doi: 10.2967/jnumed.113.132647. Epub 2014 Mar 20.

16.

Selective worsening of brain injury biomarker abnormalities in cognitively normal elderly persons with β-amyloidosis.

Knopman DS, Jack CR Jr, Wiste HJ, Weigand SD, Vemuri P, Lowe VJ, Kantarci K, Gunter JL, Senjem ML, Mielke MM, Roberts RO, Boeve BF, Petersen RC.

JAMA Neurol. 2013 Aug;70(8):1030-8. doi: 10.1001/jamaneurol.2013.182.

17.

Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.

Laforce R Jr, Tosun D, Ghosh P, Lehmann M, Madison CM, Weiner MW, Miller BL, Jagust WJ, Rabinovici GD.

Neuroimage Clin. 2014 Mar 19;4:508-16. doi: 10.1016/j.nicl.2014.03.005. eCollection 2014.

18.

Role of family history for Alzheimer biomarker abnormalities in the adult children study.

Xiong C, Roe CM, Buckles V, Fagan A, Holtzman D, Balota D, Duchek J, Storandt M, Mintun M, Grant E, Snyder AZ, Head D, Benzinger TL, Mettenburg J, Csernansky J, Morris JC.

Arch Neurol. 2011 Oct;68(10):1313-9. doi: 10.1001/archneurol.2011.208.

19.

Nutrient intake and brain biomarkers of Alzheimer's disease in at-risk cognitively normal individuals: a cross-sectional neuroimaging pilot study.

Mosconi L, Murray J, Davies M, Williams S, Pirraglia E, Spector N, Tsui WH, Li Y, Butler T, Osorio RS, Glodzik L, Vallabhajosula S, McHugh P, Marmar CR, de Leon MJ.

BMJ Open. 2014 Jun 24;4(6):e004850. doi: 10.1136/bmjopen-2014-004850.

20.

Associations between white matter microstructure and amyloid burden in preclinical Alzheimer's disease: A multimodal imaging investigation.

Racine AM, Adluru N, Alexander AL, Christian BT, Okonkwo OC, Oh J, Cleary CA, Birdsill A, Hillmer AT, Murali D, Barnhart TE, Gallagher CL, Carlsson CM, Rowley HA, Dowling NM, Asthana S, Sager MA, Bendlin BB, Johnson SC.

Neuroimage Clin. 2014 Feb 19;4:604-14. doi: 10.1016/j.nicl.2014.02.001. eCollection 2014.

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