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Items: 1 to 20 of 119

1.

Skin sensitizers differentially regulate signaling pathways in MUTZ-3 cells in relation to their individual potency.

Albrekt AS, Johansson H, Börje A, Borrebaeck C, Lindstedt M.

BMC Pharmacol Toxicol. 2014 Feb 11;15:5. doi: 10.1186/2050-6511-15-5.

2.

Genomic allergen rapid detection in-house validation--a proof of concept.

Johansson H, Rydnert F, Kühnl J, Schepky A, Borrebaeck C, Lindstedt M.

Toxicol Sci. 2014 Jun;139(2):362-70. doi: 10.1093/toxsci/kfu046. Epub 2014 Mar 27.

PMID:
24675087
3.

The GARD assay for assessment of chemical skin sensitizers.

Johansson H, Albrekt AS, Borrebaeck CA, Lindstedt M.

Toxicol In Vitro. 2013 Apr;27(3):1163-9. doi: 10.1016/j.tiv.2012.05.019. Epub 2012 Sep 29.

4.

A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests.

Johansson H, Lindstedt M, Albrekt AS, Borrebaeck CA.

BMC Genomics. 2011 Aug 8;12:399. doi: 10.1186/1471-2164-12-399.

5.

From genome-wide arrays to tailor-made biomarker readout - Progress towards routine analysis of skin sensitizing chemicals with GARD.

Forreryd A, Zeller KS, Lindberg T, Johansson H, Lindstedt M.

Toxicol In Vitro. 2016 Dec;37:178-188. doi: 10.1016/j.tiv.2016.09.013. Epub 2016 Sep 13.

6.

Evaluation of high throughput gene expression platforms using a genomic biomarker signature for prediction of skin sensitization.

Forreryd A, Johansson H, Albrekt AS, Lindstedt M.

BMC Genomics. 2014 May 16;15:379. doi: 10.1186/1471-2164-15-379.

7.

An in vitro method for detecting chemical sensitization using human reconstructed skin models and its applicability to cosmetic, pharmaceutical, and medical device safety testing.

McKim JM Jr, Keller DJ 3rd, Gorski JR.

Cutan Ocul Toxicol. 2012 Dec;31(4):292-305. doi: 10.3109/15569527.2012.667031. Epub 2012 Apr 12.

PMID:
22494060
8.

Prediction of chemical respiratory sensitizers using GARD, a novel in vitro assay based on a genomic biomarker signature.

Forreryd A, Johansson H, Albrekt AS, Borrebaeck CA, Lindstedt M.

PLoS One. 2015 Mar 11;10(3):e0118808. doi: 10.1371/journal.pone.0118808. eCollection 2015.

9.

Evaluation of selected biomarkers for the detection of chemical sensitization in human skin: a comparative study applying THP-1, MUTZ-3 and primary dendritic cells in culture.

Hitzler M, Bergert A, Luch A, Peiser M.

Toxicol In Vitro. 2013 Sep;27(6):1659-69. doi: 10.1016/j.tiv.2013.04.009. Epub 2013 Apr 26.

PMID:
23624239
10.

The GARD platform for potency assessment of skin sensitizing chemicals.

Zeller KS, Forreryd A, Lindberg T, Gradin R, Chawade A, Lindstedt M.

ALTEX. 2017;34(4):539-559. doi: 10.14573/altex.1701101. Epub 2017 Apr 12.

11.

Development of a new in vitro skin sensitization assay (Epidermal Sensitization Assay; EpiSensA) using reconstructed human epidermis.

Saito K, Nukada Y, Takenouchi O, Miyazawa M, Sakaguchi H, Nishiyama N.

Toxicol In Vitro. 2013 Dec;27(8):2213-24. doi: 10.1016/j.tiv.2013.08.007. Epub 2013 Aug 30.

PMID:
23999411
12.

Comparative DNA microarray analysis of human monocyte derived dendritic cells and MUTZ-3 cells exposed to the moderate skin sensitizer cinnamaldehyde.

Python F, Goebel C, Aeby P.

Toxicol Appl Pharmacol. 2009 Sep 15;239(3):273-83. doi: 10.1016/j.taap.2009.06.003. Epub 2009 Jun 12.

PMID:
19524605
13.

Prediction of the contact sensitizing potential of chemicals using analysis of gene expression changes in human THP-1 monocytes.

Arkusz J, Stępnik M, Sobala W, Dastych J.

Toxicol Lett. 2010 Nov 10;199(1):51-9. doi: 10.1016/j.toxlet.2010.08.005. Epub 2010 Aug 14.

PMID:
20713136
14.

Evaluation of the GARD assay in a blind Cosmetics Europe study.

Johansson H, Gradin R, Forreryd A, Agemark M, Zeller K, Johansson A, Larne O, van Vliet E, Borrebaeck C, Lindstedt M.

ALTEX. 2017;34(4):515-523. doi: 10.14573/altex.1701121. Epub 2017 Feb 17.

15.

Quantitative relationship between the local lymph node assay and human skin sensitization assays.

Schneider K, Akkan Z.

Regul Toxicol Pharmacol. 2004 Jun;39(3):245-55.

PMID:
15135206
17.

An in vitro human skin test for assessing sensitization potential.

Ahmed SS, Wang XN, Fielding M, Kerry A, Dickinson I, Munuswamy R, Kimber I, Dickinson AM.

J Appl Toxicol. 2016 May;36(5):669-84. doi: 10.1002/jat.3197. Epub 2015 Aug 7.

PMID:
26251951
18.

Use of IL-8 release and p38 MAPK activation in THP-1 cells to identify allergens and to assess their potency in vitro.

Mitjans M, Galbiati V, Lucchi L, Viviani B, Marinovich M, Galli CL, Corsini E.

Toxicol In Vitro. 2010 Sep;24(6):1803-9. doi: 10.1016/j.tiv.2010.06.001. Epub 2010 Jun 9.

PMID:
20541004
19.

Putting the parts together: combining in vitro methods to test for skin sensitizing potentials.

Bauch C, Kolle SN, Ramirez T, Eltze T, Fabian E, Mehling A, Teubner W, van Ravenzwaay B, Landsiedel R.

Regul Toxicol Pharmacol. 2012 Aug;63(3):489-504. doi: 10.1016/j.yrtph.2012.05.013. Epub 2012 Jun 1. Erratum in: Regul Toxicol Pharmacol. 2012 Nov;64(2):285.

PMID:
22659254
20.

Gene expression profiles and pathways in skin inflammation induced by three different sensitizers and an irritant.

Ku HO, Jeong SH, Kang HG, Pyo HM, Cho JH, Son SW, Yun SM, Ryu DY.

Toxicol Lett. 2009 Oct 28;190(2):231-7. doi: 10.1016/j.toxlet.2009.07.022. Epub 2009 Jul 30.

PMID:
19647056

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