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Items: 1 to 20 of 120

1.

Natural disruption of two regulatory networks in serotype M3 group A Streptococcus isolates contributes to the virulence factor profile of this hypervirulent serotype.

Cao TN, Liu Z, Cao TH, Pflughoeft KJ, Treviño J, Danger JL, Beres SB, Musser JM, Sumby P.

Infect Immun. 2014 May;82(5):1744-54. doi: 10.1128/IAI.01639-13. Epub 2014 Feb 10.

2.

RivR is a negative regulator of virulence factor expression in group A Streptococcus.

Treviño J, Liu Z, Cao TN, Ramirez-Peña E, Sumby P.

Infect Immun. 2013 Jan;81(1):364-72. doi: 10.1128/IAI.00703-12. Epub 2012 Nov 12.

3.

The small regulatory RNA FasX enhances group A Streptococcus virulence and inhibits pilus expression via serotype-specific targets.

Danger JL, Cao TN, Cao TH, Sarkar P, Treviño J, Pflughoeft KJ, Sumby P.

Mol Microbiol. 2015 Apr;96(2):249-62. doi: 10.1111/mmi.12935. Epub 2015 Feb 4.

4.

Multimerization of the Virulence-Enhancing Group A Streptococcus Transcription Factor RivR Is Required for Regulatory Activity.

Ramalinga A, Danger JL, Makthal N, Kumaraswami M, Sumby P.

J Bacteriol. 2016 Dec 13;199(1). pii: e00452-16. Print 2017 Jan 1.

5.

The group A Streptococcus small regulatory RNA FasX enhances streptokinase activity by increasing the stability of the ska mRNA transcript.

Ramirez-Peña E, Treviño J, Liu Z, Perez N, Sumby P.

Mol Microbiol. 2010 Dec;78(6):1332-47. doi: 10.1111/j.1365-2958.2010.07427.x. Epub 2010 Oct 22.

6.

Effects of the ERES pathogenicity region regulator Ralp3 on Streptococcus pyogenes serotype M49 virulence factor expression.

Siemens N, Fiedler T, Normann J, Klein J, Münch R, Patenge N, Kreikemeyer B.

J Bacteriol. 2012 Jul;194(14):3618-26. doi: 10.1128/JB.00227-12. Epub 2012 Apr 27.

7.

Genomic Characterization of a Pattern D Streptococcus pyogenes emm53 Isolate Reveals a Genetic Rationale for Invasive Skin Tropicity.

Bao YJ, Liang Z, Mayfield JA, Donahue DL, Carothers KE, Lee SW, Ploplis VA, Castellino FJ.

J Bacteriol. 2016 May 27;198(12):1712-24. doi: 10.1128/JB.01019-15. Print 2016 Jun 15.

8.

A truncation in the regulator RocA underlies heightened capsule expression in serotype M3 group A streptococci.

Lynskey NN, Turner CE, Heng LS, Sriskandan S.

Infect Immun. 2015 Apr;83(4):1732-3. doi: 10.1128/IAI.02892-14. No abstract available.

9.

Reply to "A truncation in the regulator RocA underlies heightened capsule expression in serotype M3 group A streptococci".

Miller EW, Pflughoeft KJ, Sumby P.

Infect Immun. 2015 Apr;83(4):1734. doi: 10.1128/IAI.03162-14. No abstract available.

10.

A natural inactivating mutation in the CovS component of the CovRS regulatory operon in a pattern D Streptococcal pyogenes strain influences virulence-associated genes.

Liang Z, Zhang Y, Agrahari G, Chandrahas V, Glinton K, Donahue DL, Balsara RD, Ploplis VA, Castellino FJ.

J Biol Chem. 2013 Mar 1;288(9):6561-73. doi: 10.1074/jbc.M112.442657. Epub 2013 Jan 13.

11.

Characterization of the effect of the histidine kinase CovS on response regulator phosphorylation in group A Streptococcus.

Horstmann N, Sahasrabhojane P, Saldaña M, Ajami NJ, Flores AR, Sumby P, Liu CG, Yao H, Su X, Thompson E, Shelburne SA.

Infect Immun. 2015 Mar;83(3):1068-77. doi: 10.1128/IAI.02659-14. Epub 2015 Jan 5.

12.

The FasX Small Regulatory RNA Negatively Regulates the Expression of Two Fibronectin-Binding Proteins in Group A Streptococcus.

Danger JL, Makthal N, Kumaraswami M, Sumby P.

J Bacteriol. 2015 Dec;197(23):3720-30. doi: 10.1128/JB.00530-15. Epub 2015 Sep 21.

13.
14.

The Streptococcus pyogenes serotype M49 Nra-Ralp3 transcriptional regulatory network and its control of virulence factor expression from the novel eno ralp3 epf sagA pathogenicity region.

Kreikemeyer B, Nakata M, Köller T, Hildisch H, Kourakos V, Standar K, Kawabata S, Glocker MO, Podbielski A.

Infect Immun. 2007 Dec;75(12):5698-710. Epub 2007 Sep 24.

15.

Regulatory rewiring confers serotype-specific hyper-virulence in the human pathogen group A Streptococcus.

Miller EW, Danger JL, Ramalinga AB, Horstmann N, Shelburne SA, Sumby P.

Mol Microbiol. 2015 Oct;98(3):473-89. doi: 10.1111/mmi.13136. Epub 2015 Aug 14.

16.

Natural variation in the promoter of the gene encoding the Mga regulator alters host-pathogen interactions in group a Streptococcus carrier strains.

Flores AR, Olsen RJ, Wunsche A, Kumaraswami M, Shelburne SA 3rd, Carroll RK, Musser JM.

Infect Immun. 2013 Nov;81(11):4128-38. doi: 10.1128/IAI.00405-13. Epub 2013 Aug 26.

17.

Serotype M3 and M28 Group A Streptococci Have Distinct Capacities to Evade Neutrophil and TNF-α Responses and to Invade Soft Tissues.

Stetzner ZW, Li D, Feng W, Liu M, Liu G, Wiley J, Lei B.

PLoS One. 2015 Jun 5;10(6):e0129417. doi: 10.1371/journal.pone.0129417. eCollection 2015.

18.

Natural variant of collagen-like protein a in serotype M3 group a Streptococcus increases adherence and decreases invasive potential.

Flores AR, Jewell BE, Versalovic EM, Olsen RJ, Bachert BA, Lukomski S, Musser JM.

Infect Immun. 2015 Mar;83(3):1122-9. doi: 10.1128/IAI.02860-14. Epub 2015 Jan 5.

19.

IgG protease Mac/IdeS is not essential for phagocyte resistance or mouse virulence of M1T1 group A Streptococcus.

Okumura CY, Anderson EL, Döhrmann S, Tran DN, Olson J, von Pawel-Rammingen U, Nizet V.

MBio. 2013 Jul 30;4(4). pii: e00499-13. doi: 10.1128/mBio.00499-13.

20.

A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection.

Shelburne SA, Olsen RJ, Suber B, Sahasrabhojane P, Sumby P, Brennan RG, Musser JM.

PLoS Pathog. 2010 Mar 19;6(3):e1000817. doi: 10.1371/journal.ppat.1000817.

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