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Items: 1 to 20 of 110

1.

The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis.

Bielli P, Busà R, Di Stasi SM, Munoz MJ, Botti F, Kornblihtt AR, Sette C.

EMBO Rep. 2014 Apr;15(4):419-27. doi: 10.1002/embr.201338241. Epub 2014 Feb 10.

2.

The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x.

Paronetto MP, Achsel T, Massiello A, Chalfant CE, Sette C.

J Cell Biol. 2007 Mar 26;176(7):929-39. Epub 2007 Mar 19.

3.

Fyn requires HnRNPA2B1 and Sam68 to synergistically regulate apoptosis in pancreatic cancer.

Chen ZY, Cai L, Zhu J, Chen M, Chen J, Li ZH, Liu XD, Wang SG, Bie P, Jiang P, Dong JH, Li XW.

Carcinogenesis. 2011 Oct;32(10):1419-26. doi: 10.1093/carcin/bgr088. Epub 2011 Jun 3.

PMID:
21642356
4.

Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5' splice site selection.

Bielli P, Bordi M, Di Biasio V, Sette C.

Nucleic Acids Res. 2014 Oct 29;42(19):12070-81. doi: 10.1093/nar/gku922. Epub 2014 Oct 7.

5.

Nuclear matrix-associated protein SMAR1 regulates alternative splicing via HDAC6-mediated deacetylation of Sam68.

Nakka KK, Chaudhary N, Joshi S, Bhat J, Singh K, Chatterjee S, Malhotra R, De A, Santra MK, Dilworth FJ, Chattopadhyay S.

Proc Natl Acad Sci U S A. 2015 Jun 30;112(26):E3374-83. doi: 10.1073/pnas.1418603112. Epub 2015 Jun 15.

6.

Long non-coding RNA INXS is a critical mediator of BCL-XS induced apoptosis.

DeOcesano-Pereira C, Amaral MS, Parreira KS, Ayupe AC, Jacysyn JF, Amarante-Mendes GP, Reis EM, Verjovski-Almeida S.

Nucleic Acids Res. 2014 Jul;42(13):8343-55. doi: 10.1093/nar/gku561. Epub 2014 Jul 3. Retraction in: Nucleic Acids Res. 2016 Nov 2;44(19):9518.

7.

The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7.

Stockley J, Markert E, Zhou Y, Robson CN, Elliott DJ, Lindberg J, Leung HY, Rajan P.

Sci Rep. 2015 Aug 27;5:13426. doi: 10.1038/srep13426.

8.

Antagonistic effects of the SRp30c protein and cryptic 5' splice sites on the alternative splicing of the apoptotic regulator Bcl-x.

Cloutier P, Toutant J, Shkreta L, Goekjian S, Revil T, Chabot B.

J Biol Chem. 2008 Aug 1;283(31):21315-24. doi: 10.1074/jbc.M800353200. Epub 2008 Jun 5.

9.

Sam68 regulates EMT through alternative splicing-activated nonsense-mediated mRNA decay of the SF2/ASF proto-oncogene.

Valacca C, Bonomi S, Buratti E, Pedrotti S, Baralle FE, Sette C, Ghigna C, Biamonti G.

J Cell Biol. 2010 Oct 4;191(1):87-99. doi: 10.1083/jcb.201001073. Epub 2010 Sep 27.

10.

Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.

Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B.

Mol Cell Biol. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11. Epub 2011 Dec 27.

11.

Pro-apoptotic effects of splice-switching oligonucleotides targeting Bcl-x pre-mRNA in human glioma cell lines.

Li Z, Li Q, Han L, Tian N, Liang Q, Li Y, Zhao X, Du C, Tian Y.

Oncol Rep. 2016 Feb;35(2):1013-9. doi: 10.3892/or.2015.4465. Epub 2015 Nov 30.

PMID:
26718027
12.

Loss of Pnn expression results in mouse early embryonic lethality and cellular apoptosis through SRSF1-mediated alternative expression of Bcl-xS and ICAD.

Leu S, Lin YM, Wu CH, Ouyang P.

J Cell Sci. 2012 Jul 1;125(Pt 13):3164-72. doi: 10.1242/jcs.100859. Epub 2012 Mar 27.

13.

Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68.

Paronetto MP, Cappellari M, Busà R, Pedrotti S, Vitali R, Comstock C, Hyslop T, Knudsen KE, Sette C.

Cancer Res. 2010 Jan 1;70(1):229-39. doi: 10.1158/0008-5472.CAN-09-2788. Epub 2009 Dec 22.

14.

Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing.

Montes M, Coiras M, Becerra S, Moreno-Castro C, Mateos E, Majuelos J, Oliver FJ, Hernández-Munain C, Alcamí J, Suñé C.

PLoS One. 2015 Oct 13;10(10):e0139812. doi: 10.1371/journal.pone.0139812. eCollection 2015.

15.

The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy.

Pedrotti S, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Stamm S, Manley JL, Sette C.

EMBO J. 2010 Apr 7;29(7):1235-47. doi: 10.1038/emboj.2010.19. Epub 2010 Feb 25.

16.

Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection.

Zhou A, Ou AC, Cho A, Benz EJ Jr, Huang SC.

Mol Cell Biol. 2008 Oct;28(19):5924-36. doi: 10.1128/MCB.00560-08. Epub 2008 Jul 28.

17.

The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor.

Rajan P, Gaughan L, Dalgliesh C, El-Sherif A, Robson CN, Leung HY, Elliott DJ.

J Pathol. 2008 May;215(1):67-77. doi: 10.1002/path.2324.

PMID:
18273831
18.

The transcriptional co-activator SND1 is a novel regulator of alternative splicing in prostate cancer cells.

Cappellari M, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Saarikettu J, Silvennoinen O, Sette C.

Oncogene. 2014 Jul 17;33(29):3794-802. doi: 10.1038/onc.2013.360. Epub 2013 Sep 2.

PMID:
23995791
19.

Co-regulation of survival of motor neuron and Bcl-xL expression: implications for neuroprotection in spinal muscular atrophy.

Anderton RS, Price LL, Turner BJ, Meloni BP, Mitrpant C, Mastaglia FL, Goh C, Wilton SD, Boulos S.

Neuroscience. 2012 Sep 18;220:228-36. doi: 10.1016/j.neuroscience.2012.06.042. Epub 2012 Jun 23.

PMID:
22732506
20.

Melanoma Differentiation-associated Gene 7/IL-24 Exerts Cytotoxic Effects by Altering the Alternative Splicing of Bcl-x Pre-mRNA via the SRC/PKCδ Signaling Axis.

Shapiro BA, Vu NT, Shultz MD, Shultz JC, Mietla JA, Gouda MM, Yacoub A, Dent P, Fisher PB, Park MA, Chalfant CE.

J Biol Chem. 2016 Oct 7;291(41):21669-21681. Epub 2016 Aug 12.

PMID:
27519412

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