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Src tyrosine kinase signaling antagonizes nuclear localization of FOXO and inhibits its transcription factor activity.

Bülow MH, Bülow TR, Hoch M, Pankratz MJ, Jünger MA.

Sci Rep. 2014 Feb 11;4:4048. doi: 10.1038/srep04048. Erratum in: Sci Rep. 2014;4:5137.


The Drosophila forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling.

Jünger MA, Rintelen F, Stocker H, Wasserman JD, Végh M, Radimerski T, Greenberg ME, Hafen E.

J Biol. 2003;2(3):20. Epub 2003 Aug 7.


Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway.

Puig O, Marr MT, Ruhf ML, Tjian R.

Genes Dev. 2003 Aug 15;17(16):2006-20. Epub 2003 Jul 31.


Expression of Drosophila FOXO regulates growth and can phenocopy starvation.

Kramer JM, Davidge JT, Lockyer JM, Staveley BE.

BMC Dev Biol. 2003 Jul 5;3:5. Epub 2003 Jul 5.


dFOXO-independent effects of reduced insulin-like signaling in Drosophila.

Slack C, Giannakou ME, Foley A, Goss M, Partridge L.

Aging Cell. 2011 Oct;10(5):735-48. doi: 10.1111/j.1474-9726.2011.00707.x. Epub 2011 May 6.


The drosophila T-box transcription factor midline functions within Insulin/Akt and c-Jun-N terminal kinase stress-reactive signaling pathways to regulate interommatial bristle formation and cell survival.

Chen QB, Das S, Visic P, Buford KD, Zong Y, Buti W, Odom KR, Lee H, Leal SM.

Mech Dev. 2015 May;136:8-29. doi: 10.1016/j.mod.2015.02.005. Epub 2015 Mar 5.


A role for Drosophila dFoxO and dFoxO 5'UTR internal ribosomal entry sites during fasting.

Villa-Cuesta E, Sage BT, Tatar M.

PLoS One. 2010 Jul 9;5(7):e11521. doi: 10.1371/journal.pone.0011521.


Transcriptional feedback control of insulin receptor by dFOXO/FOXO1.

Puig O, Tjian R.

Genes Dev. 2005 Oct 15;19(20):2435-46.


The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycin.

Bülow MH, Aebersold R, Pankratz MJ, Jünger MA.

PLoS One. 2010 Dec 31;5(12):e15171. doi: 10.1371/journal.pone.0015171.


dFoxO promotes Wingless signaling in Drosophila.

Zhang S, Guo X, Chen C, Chen Y, Li J, Sun Y, Wu C, Yang Y, Jiang C, Li W, Xue L.

Sci Rep. 2016 Mar 3;6:22348. doi: 10.1038/srep22348.


Understanding Forkhead box class O function: lessons from Drosophila melanogaster.

Puig O, Mattila J.

Antioxid Redox Signal. 2011 Feb 15;14(4):635-47. doi: 10.1089/ars.2010.3407. Epub 2010 Oct 20. Review.


d4eBP acts downstream of both dTOR and dFoxo to modulate cardiac functional aging in Drosophila.

Wessells R, Fitzgerald E, Piazza N, Ocorr K, Morley S, Davies C, Lim HY, Elmén L, Hayes M, Oldham S, Bodmer R.

Aging Cell. 2009 Sep;8(5):542-52. doi: 10.1111/j.1474-9726.2009.00504.x. Epub 2009 Jul 9.


Src family kinases are required for WNT5 signaling through the Derailed/RYK receptor in the Drosophila embryonic central nervous system.

Wouda RR, Bansraj MR, de Jong AW, Noordermeer JN, Fradkin LG.

Development. 2008 Jul;135(13):2277-87. doi: 10.1242/dev.017319.


Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling.

Alic N, Andrews TD, Giannakou ME, Papatheodorou I, Slack C, Hoddinott MP, Cochemé HM, Schuster EF, Thornton JM, Partridge L.

Mol Syst Biol. 2011 Jun 21;7:502. doi: 10.1038/msb.2011.36.


Forkhead, a new cross regulator of metabolism and innate immunity downstream of TOR in Drosophila.

Varma D, Bülow MH, Pesch YY, Loch G, Hoch M.

J Insect Physiol. 2014 Oct;69:80-8. doi: 10.1016/j.jinsphys.2014.04.006. Epub 2014 May 16.


Insulin receptor substrate chico acts with the transcription factor FOXO to extend Drosophila lifespan.

Yamamoto R, Tatar M.

Aging Cell. 2011 Aug;10(4):729-32. doi: 10.1111/j.1474-9726.2011.00716.x. Epub 2011 May 27.


Src controls tumorigenesis via JNK-dependent regulation of the Hippo pathway in Drosophila.

Enomoto M, Igaki T.

EMBO Rep. 2013 Jan;14(1):65-72. doi: 10.1038/embor.2012.185. Epub 2012 Nov 30.


Drosophila FoxO regulates organism size and stress resistance through an adenylate cyclase.

Mattila J, Bremer A, Ahonen L, Kostiainen R, Puig O.

Mol Cell Biol. 2009 Oct;29(19):5357-65. doi: 10.1128/MCB.00302-09. Epub 2009 Aug 3.


Dynamics of the action of dFOXO on adult mortality in Drosophila.

Giannakou ME, Goss M, Jacobson J, Vinti G, Leevers SJ, Partridge L.

Aging Cell. 2007 Aug;6(4):429-38. Epub 2007 Apr 26.

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