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Items: 1 to 20 of 423

1.

Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation.

Xu PX, Wang SW, Yu XL, Su YJ, Wang T, Zhou WW, Zhang H, Wang YJ, Liu RT.

Behav Brain Res. 2014 May 1;264:173-80. doi: 10.1016/j.bbr.2014.02.002. Epub 2014 Feb 7.

PMID:
24512768
2.

Rutin inhibits β-amyloid aggregation and cytotoxicity, attenuates oxidative stress, and decreases the production of nitric oxide and proinflammatory cytokines.

Wang SW, Wang YJ, Su YJ, Zhou WW, Yang SG, Zhang R, Zhao M, Li YN, Zhang ZP, Zhan DW, Liu RT.

Neurotoxicology. 2012 Jun;33(3):482-90. doi: 10.1016/j.neuro.2012.03.003. Epub 2012 Mar 15.

PMID:
22445961
3.

Decreasing oxidative stress and neuroinflammation with a multifunctional peptide rescues memory deficits in mice with Alzheimer disease.

Zhou WW, Lu S, Su YJ, Xue D, Yu XL, Wang SW, Zhang H, Xu PX, Xie XX, Liu RT.

Free Radic Biol Med. 2014 Sep;74:50-63. doi: 10.1016/j.freeradbiomed.2014.06.013. Epub 2014 Jun 21.

PMID:
24960578
4.

4-O-methylhonokiol attenuated memory impairment through modulation of oxidative damage of enzymes involving amyloid-β generation and accumulation in a mouse model of Alzheimer's disease.

Choi IS, Lee YJ, Choi DY, Lee YK, Lee YH, Kim KH, Kim YH, Jeon YH, Kim EH, Han SB, Jung JK, Yun YP, Oh KW, Hwang DY, Hong JT.

J Alzheimers Dis. 2011;27(1):127-41. doi: 10.3233/JAD-2011-110545.

PMID:
21799245
5.

Soluble Aβ levels correlate with cognitive deficits in the 12-month-old APPswe/PS1dE9 mouse model of Alzheimer's disease.

Zhang W, Hao J, Liu R, Zhang Z, Lei G, Su C, Miao J, Li Z.

Behav Brain Res. 2011 Sep 23;222(2):342-50. doi: 10.1016/j.bbr.2011.03.072. Epub 2011 Apr 14.

PMID:
21513747
6.

4-O-methylhonokiol prevents memory impairment in the Tg2576 transgenic mice model of Alzheimer's disease via regulation of β-secretase activity.

Lee YJ, Choi DY, Lee YK, Lee YM, Han SB, Kim YH, Kim KH, Nam SY, Lee BJ, Kang JK, Yun YW, Oh KW, Hong JT.

J Alzheimers Dis. 2012;29(3):677-90. doi: 10.3233/JAD-2012-111835.

PMID:
22330831
7.

L-3-n-butylphthalide improves cognitive impairment and reduces amyloid-beta in a transgenic model of Alzheimer's disease.

Peng Y, Sun J, Hon S, Nylander AN, Xia W, Feng Y, Wang X, Lemere CA.

J Neurosci. 2010 Jun 16;30(24):8180-9. doi: 10.1523/JNEUROSCI.0340-10.2010.

8.

Vitamin C restores behavioral deficits and amyloid-β oligomerization without affecting plaque formation in a mouse model of Alzheimer's disease.

Murakami K, Murata N, Ozawa Y, Kinoshita N, Irie K, Shirasawa T, Shimizu T.

J Alzheimers Dis. 2011;26(1):7-18. doi: 10.3233/JAD-2011-101971.

PMID:
21558647
9.

Alpha-tocopherol quinine ameliorates spatial memory deficits by reducing beta-amyloid oligomers, neuroinflammation and oxidative stress in transgenic mice with Alzheimer's disease.

Wang SW, Yang SG, Liu W, Zhang YX, Xu PX, Wang T, Ling TJ, Liu RT.

Behav Brain Res. 2016 Jan 1;296:109-117. doi: 10.1016/j.bbr.2015.09.003. Epub 2015 Sep 7.

PMID:
26358659
10.

S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice.

Zhang W, Zhang W, Li Z, Hao J, Zhang Z, Liu L, Mao N, Miao J, Zhang L.

Pharmacol Biochem Behav. 2012 Jan;100(3):361-9. doi: 10.1016/j.pbb.2011.09.012. Epub 2011 Oct 2.

PMID:
21993310
11.

Rutin inhibits amylin-induced neurocytotoxicity and oxidative stress.

Yu XL, Li YN, Zhang H, Su YJ, Zhou WW, Zhang ZP, Wang SW, Xu PX, Wang YJ, Liu RT.

Food Funct. 2015 Oct;6(10):3296-306. doi: 10.1039/c5fo00500k.

PMID:
26242245
12.

Early memory deficits precede plaque deposition in APPswe/PS1dE9 mice: involvement of oxidative stress and cholinergic dysfunction.

Zhang W, Bai M, Xi Y, Hao J, Liu L, Mao N, Su C, Miao J, Li Z.

Free Radic Biol Med. 2012 Apr 15;52(8):1443-52. doi: 10.1016/j.freeradbiomed.2012.01.023. Epub 2012 Feb 2.

PMID:
22342520
13.

A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease.

Jeon S, Bose S, Hur J, Jun K, Kim YK, Cho KS, Koo BS.

J Ethnopharmacol. 2011 Sep 1;137(1):783-9. doi: 10.1016/j.jep.2011.06.046. Epub 2011 Jul 5.

PMID:
21762767
14.

K114 inhibits A-beta aggregation and inflammation in vitro and in vivo in AD/Tg mice.

Zhang YH, Mann D, Raymick J, Sarkar S, Paule MG, Lahiri DK, Dumas M, Bell-Cohen A, Schmued LC.

Curr Alzheimer Res. 2014 Mar;11(3):299-308.

PMID:
24552157
15.

Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of Alzheimer's Disease.

Tapia-Rojas C, Aranguiz F, Varela-Nallar L, Inestrosa NC.

Brain Pathol. 2016 Jan;26(1):62-74. doi: 10.1111/bpa.12255. Epub 2015 May 7.

PMID:
25763997
16.

Changes in the brain and plasma Aβ peptide levels with age and its relationship with cognitive impairment in the APPswe/PS1dE9 mouse model of Alzheimer's disease.

Izco M, Martínez P, Corrales A, Fandos N, García S, Insua D, Montañes M, Pérez-Grijalba V, Rueda N, Vidal V, Martínez-Cué C, Pesini P, Sarasa M.

Neuroscience. 2014 Mar 28;263:269-79. doi: 10.1016/j.neuroscience.2014.01.003. Epub 2014 Jan 18.

PMID:
24447596
17.

Alzheimer's disease like pathology induced six weeks after aggregated amyloid-beta injection in rats: increased oxidative stress and impaired long-term memory with anxiety-like behavior.

Sharma S, Verma S, Kapoor M, Saini A, Nehru B.

Neurol Res. 2016 Sep;38(9):838-50. doi: 10.1080/01616412.2016.1209337. Epub 2016 Jul 19.

PMID:
27431920
18.

Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model.

Ding Y, Qiao A, Wang Z, Goodwin JS, Lee ES, Block ML, Allsbrook M, McDonald MP, Fan GH.

J Neurosci. 2008 Nov 5;28(45):11622-34. doi: 10.1523/JNEUROSCI.3153-08.2008.

19.

The n-Butanol Fraction and Rutin from Tartary Buckwheat Improve Cognition and Memory in an In Vivo Model of Amyloid-β-Induced Alzheimer's Disease.

Choi JY, Lee JM, Lee DG, Cho S, Yoon YH, Cho EJ, Lee S.

J Med Food. 2015 Jun;18(6):631-41. doi: 10.1089/jmf.2014.3292. Epub 2015 Mar 18.

PMID:
25785882
20.

A multifunctional peptide rescues memory deficits in Alzheimer's disease transgenic mice by inhibiting Aβ42-induced cytotoxicity and increasing microglial phagocytosis.

Xue D, Zhao M, Wang YJ, Wang L, Yang Y, Wang SW, Zhang R, Zhao Y, Liu RT.

Neurobiol Dis. 2012 Jun;46(3):701-9. doi: 10.1016/j.nbd.2012.03.013. Epub 2012 Mar 9.

PMID:
22426388

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