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A committed precursor to innate lymphoid cells.

Constantinides MG, McDonald BD, Verhoef PA, Bendelac A.

Nature. 2014 Apr 17;508(7496):397-401. doi: 10.1038/nature13047.


PLZF expression maps the early stages of ILC1 lineage development.

Constantinides MG, Gudjonson H, McDonald BD, Ishizuka IE, Verhoef PA, Dinner AR, Bendelac A.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5123-8. doi: 10.1073/pnas.1423244112.


Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages.

Klose CS, Flach M, Möhle L, Rogell L, Hoyler T, Ebert K, Fabiunke C, Pfeifer D, Sexl V, Fonseca-Pereira D, Domingues RG, Veiga-Fernandes H, Arnold SJ, Busslinger M, Dunay IR, Tanriver Y, Diefenbach A.

Cell. 2014 Apr 10;157(2):340-56. doi: 10.1016/j.cell.2014.03.030.


Single-cell analysis defines the divergence between the innate lymphoid cell lineage and lymphoid tissue-inducer cell lineage.

Ishizuka IE, Chea S, Gudjonson H, Constantinides MG, Dinner AR, Bendelac A, Golub R.

Nat Immunol. 2016 Mar;17(3):269-76. doi: 10.1038/ni.3344.


IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors.

Satoh-Takayama N, Lesjean-Pottier S, Vieira P, Sawa S, Eberl G, Vosshenrich CA, Di Santo JP.

J Exp Med. 2010 Feb 15;207(2):273-80. doi: 10.1084/jem.20092029.


NFIL3 orchestrates the emergence of common helper innate lymphoid cell precursors.

Xu W, Domingues RG, Fonseca-Pereira D, Ferreira M, Ribeiro H, Lopez-Lastra S, Motomura Y, Moreira-Santos L, Bihl F, Braud V, Kee B, Brady H, Coles MC, Vosshenrich C, Kubo M, Di Santo JP, Veiga-Fernandes H.

Cell Rep. 2015 Mar 31;10(12):2043-54. doi: 10.1016/j.celrep.2015.02.057.


The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor.

Yu X, Wang Y, Deng M, Li Y, Ruhn KA, Zhang CC, Hooper LV.

Elife. 2014 Oct 13;3. doi: 10.7554/eLife.04406.


Development of human natural killer cells and other innate lymphoid cells.

Montaldo E, Vacca P, Moretta L, Mingari MC.

Semin Immunol. 2014 Apr;26(2):107-13. doi: 10.1016/j.smim.2014.01.006. Review.


An in vitro model of innate lymphoid cell function and differentiation.

Allan DS, Kirkham CL, Aguilar OA, Qu LC, Chen P, Fine JH, Serra P, Awong G, Gommerman JL, Zúñiga-Pflücker JC, Carlyle JR.

Mucosal Immunol. 2015 Mar;8(2):340-51. doi: 10.1038/mi.2014.71.


Identification of the earliest NK-cell precursor in the mouse BM.

Carotta S, Pang SH, Nutt SL, Belz GT.

Blood. 2011 May 19;117(20):5449-52. doi: 10.1182/blood-2010-11-318956.


Commitment to natural killer cells requires the helix-loop-helix inhibitor Id2.

Ikawa T, Fujimoto S, Kawamoto H, Katsura Y, Yokota Y.

Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5164-9.


Identification of diverse innate lymphoid cells in human decidua.

Vacca P, Montaldo E, Croxatto D, Loiacono F, Canegallo F, Venturini PL, Moretta L, Mingari MC.

Mucosal Immunol. 2015 Mar;8(2):254-64. doi: 10.1038/mi.2014.63.


Interleukin-21 induces the differentiation of human umbilical cord blood CD34-lineage- cells into pseudomature lytic NK cells.

Bonanno G, Mariotti A, Procoli A, Corallo M, Scambia G, Pierelli L, Rutella S.

BMC Immunol. 2009 Aug 27;10:46. doi: 10.1186/1471-2172-10-46.


Gata3 drives development of RORγt+ group 3 innate lymphoid cells.

Serafini N, Klein Wolterink RG, Satoh-Takayama N, Xu W, Vosshenrich CA, Hendriks RW, Di Santo JP.

J Exp Med. 2014 Feb 10;211(2):199-208. doi: 10.1084/jem.20131038.


TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow.

Yang Q, Li F, Harly C, Xing S, Ye L, Xia X, Wang H, Wang X, Yu S, Zhou X, Cam M, Xue HH, Bhandoola A.

Nat Immunol. 2015 Oct;16(10):1044-50. doi: 10.1038/ni.3248.


Regulation of NK1.1 expression during lineage commitment of progenitor thymocytes.

Carlyle JR, Zúñiga-Pflücker JC.

J Immunol. 1998 Dec 15;161(12):6544-51.


Transcriptional programs define molecular characteristics of innate lymphoid cell classes and subsets.

Robinette ML, Fuchs A, Cortez VS, Lee JS, Wang Y, Durum SK, Gilfillan S, Colonna M; Immunological Genome Consortium..

Nat Immunol. 2015 Mar;16(3):306-17. doi: 10.1038/ni.3094.


The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.

Hoyler T, Klose CS, Souabni A, Turqueti-Neves A, Pfeifer D, Rawlins EL, Voehringer D, Busslinger M, Diefenbach A.

Immunity. 2012 Oct 19;37(4):634-48. doi: 10.1016/j.immuni.2012.06.020.


Characterization of the stage in natural killer cell development in 14.5-day mouse fetal liver using adult bone marrow stroma.

Lu J, Patrene KD, Appasamy PM, Herberman RB, Boggs SS.

Exp Hematol. 1999 Jun;27(6):1046-56.

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