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Honokiol inhibits epithelial-mesenchymal transition in breast cancer cells by targeting signal transducer and activator of transcription 3/Zeb1/E-cadherin axis.

Avtanski DB, Nagalingam A, Bonner MY, Arbiser JL, Saxena NK, Sharma D.

Mol Oncol. 2014 May;8(3):565-80. doi: 10.1016/j.molonc.2014.01.004.


Roles of STAT3 and ZEB1 proteins in E-cadherin down-regulation and human colorectal cancer epithelial-mesenchymal transition.

Xiong H, Hong J, Du W, Lin YW, Ren LL, Wang YC, Su WY, Wang JL, Cui Y, Wang ZH, Fang JY.

J Biol Chem. 2012 Feb 17;287(8):5819-32. doi: 10.1074/jbc.M111.295964.


Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.

Avtanski DB, Nagalingam A, Bonner MY, Arbiser JL, Saxena NK, Sharma D.

Oncotarget. 2015 Oct 6;6(30):29947-62. doi: 10.18632/oncotarget.4937.


Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1-β-catenin signaling axis in a microRNA-34a dependent manner.

Avtanski DB, Nagalingam A, Kuppusamy P, Bonner MY, Arbiser JL, Saxena NK, Sharma D.

Oncotarget. 2015 Jun 30;6(18):16396-410.


Honokiol Inhibits Constitutive and Inducible STAT3 Signaling via PU.1-Induced SHP1 Expression in Acute Myeloid Leukemia Cells.

Bi L, Yu Z, Wu J, Yu K, Hong G, Lu Z, Gao S.

Tohoku J Exp Med. 2015;237(3):163-72. doi: 10.1620/tjem.237.163.


BCL6 induces EMT by promoting the ZEB1-mediated transcription repression of E-cadherin in breast cancer cells.

Yu JM, Sun W, Hua F, Xie J, Lin H, Zhou DD, Hu ZW.

Cancer Lett. 2015 Sep 1;365(2):190-200. doi: 10.1016/j.canlet.2015.05.029.


Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression.

Bakiri L, Macho-Maschler S, Custic I, Niemiec J, Guío-Carrión A, Hasenfuss SC, Eger A, Müller M, Beug H, Wagner EF.

Cell Death Differ. 2015 Feb;22(2):336-50. doi: 10.1038/cdd.2014.157.


Stat3-coordinated Lin-28-let-7-HMGA2 and miR-200-ZEB1 circuits initiate and maintain oncostatin M-driven epithelial-mesenchymal transition.

Guo L, Chen C, Shi M, Wang F, Chen X, Diao D, Hu M, Yu M, Qian L, Guo N.

Oncogene. 2013 Nov 7;32(45):5272-82. doi: 10.1038/onc.2012.573.


Loss of the polycomb protein Mel-18 enhances the epithelial-mesenchymal transition by ZEB1 and ZEB2 expression through the downregulation of miR-205 in breast cancer.

Lee JY, Park MK, Park JH, Lee HJ, Shin DH, Kang Y, Lee CH, Kong G.

Oncogene. 2014 Mar 6;33(10):1325-35. doi: 10.1038/onc.2013.53.


CCN6 (WISP3) decreases ZEB1-mediated EMT and invasion by attenuation of IGF-1 receptor signaling in breast cancer.

Lorenzatti G, Huang W, Pal A, Cabanillas AM, Kleer CG.

J Cell Sci. 2011 May 15;124(Pt 10):1752-8. doi: 10.1242/jcs.084194.


Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression.

Ji Q, Liu X, Han Z, Zhou L, Sui H, Yan L, Jiang H, Ren J, Cai J, Li Q.

BMC Cancer. 2015 Mar 5;15:97. doi: 10.1186/s12885-015-1119-y.


HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer.

Zhang W, Shi X, Peng Y, Wu M, Zhang P, Xie R, Wu Y, Yan Q, Liu S, Wang J.

PLoS One. 2015 Jun 9;10(6):e0129603. doi: 10.1371/journal.pone.0129603.


Identification of a PEAK1/ZEB1 signaling axis during TGFβ/fibronectin-induced EMT in breast cancer.

Agajanian M, Runa F, Kelber JA.

Biochem Biophys Res Commun. 2015 Sep 25;465(3):606-12. doi: 10.1016/j.bbrc.2015.08.071.


ERbeta1 represses basal breast cancer epithelial to mesenchymal transition by destabilizing EGFR.

Thomas C, Rajapaksa G, Nikolos F, Hao R, Katchy A, McCollum CW, Bondesson M, Quinlan P, Thompson A, Krishnamurthy S, Esteva FJ, Gustafsson JÅ.

Breast Cancer Res. 2012 Nov 16;14(6):R148. doi: 10.1186/bcr3358.


An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer.

Qin Y, Tang B, Hu CJ, Xiao YF, Xie R, Yong X, Wu YY, Dong H, Yang SM.

Oncotarget. 2016 Jan 5;7(1):351-61. doi: 10.18632/oncotarget.5968.


Pterostilbene inhibits triple-negative breast cancer metastasis via inducing microRNA-205 expression and negatively modulates epithelial-to-mesenchymal transition.

Su CM, Lee WH, Wu AT, Lin YK, Wang LS, Wu CH, Yeh CT.

J Nutr Biochem. 2015 Jun;26(6):675-85. doi: 10.1016/j.jnutbio.2015.01.005.


53BP1 suppresses epithelial-mesenchymal transition by downregulating ZEB1 through microRNA-200b/429 in breast cancer.

Kong X, Ding X, Li X, Gao S, Yang Q.

Cancer Sci. 2015 Aug;106(8):982-9. doi: 10.1111/cas.12699.


Celecoxib induces epithelial-mesenchymal transition in epithelial ovarian cancer cells via regulating ZEB1 expression.

Liu R, Zheng J, Li C, Pang Y, Zheng Q, Xu X, Liu P.

Arch Gynecol Obstet. 2015 Jun;291(6):1361-9. doi: 10.1007/s00404-014-3555-3.


Epithelial to mesenchymal transition is associated with rapamycin resistance.

Holder AM, Akcakanat A, Adkins F, Evans K, Chen H, Wei C, Milton DR, Li Y, Do KA, Janku F, Meric-Bernstam F.

Oncotarget. 2015 Aug 14;6(23):19500-13.


Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.

Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.

J Cell Physiol. 2012 May;227(5):2184-95. doi: 10.1002/jcp.22954.

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