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Items: 1 to 20 of 84

1.

Monomethylfumarate reduces in vitro migration of mononuclear cells.

Dehmel T, Döbert M, Pankratz S, Leussink VI, Hartung HP, Wiendl H, Kieseier BC.

Neurol Sci. 2014 Jul;35(7):1121-5. doi: 10.1007/s10072-014-1663-2. Epub 2014 Feb 7.

PMID:
24504620
2.

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

Linker RA, Lee DH, Ryan S, van Dam AM, Conrad R, Bista P, Zeng W, Hronowsky X, Buko A, Chollate S, Ellrichmann G, Brück W, Dawson K, Goelz S, Wiese S, Scannevin RH, Lukashev M, Gold R.

Brain. 2011 Mar;134(Pt 3):678-92. doi: 10.1093/brain/awq386.

PMID:
21354971
3.

Cladribine impedes in vitro migration of mononuclear cells: a possible implication for treating multiple sclerosis.

Kopadze T, Döbert M, Leussink VI, Dehmel T, Kieseier BC.

Eur J Neurol. 2009 Mar;16(3):409-12. doi: 10.1111/j.1468-1331.2008.02433.x.

PMID:
19175384
4.

Protective effects of monomethyl fumarate at the inflamed blood-brain barrier.

Lim JL, van der Pol SM, Di Dio F, van Het Hof B, Kooij G, de Vries HE, van Horssen J.

Microvasc Res. 2016 May;105:61-9. doi: 10.1016/j.mvr.2015.12.003. Epub 2015 Dec 8.

PMID:
26679389
5.
6.

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.

Takaya K, Suzuki T, Motohashi H, Onodera K, Satomi S, Kensler TW, Yamamoto M.

Free Radic Biol Med. 2012 Aug 15;53(4):817-27. doi: 10.1016/j.freeradbiomed.2012.06.023. Epub 2012 Jun 23.

7.

Downregulation of endothelial adhesion molecules by dimethylfumarate, but not monomethylfumarate, and impairment of dynamic lymphocyte-endothelial cell interactions.

Wallbrecht K, Drick N, Hund AC, Schön MP.

Exp Dermatol. 2011 Dec;20(12):980-5. doi: 10.1111/j.1600-0625.2011.01376.x. Epub 2011 Oct 13.

PMID:
21995308
8.

Effects of monomethylfumarate on dendritic cell differentiation.

Litjens NH, Rademaker M, Ravensbergen B, Thio HB, van Dissel JT, Nibbering PH.

Br J Dermatol. 2006 Feb;154(2):211-7.

PMID:
16433787
9.

Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses.

Litjens NH, Rademaker M, Ravensbergen B, Rea D, van der Plas MJ, Thio B, Walding A, van Dissel JT, Nibbering PH.

Eur J Immunol. 2004 Feb;34(2):565-75.

10.

Influence of monomethylfumarate on monocytic cytokine formation--explanation for adverse and therapeutic effects in psoriasis?

Asadullah K, Schmid H, Friedrich M, Randow F, Volk HD, Sterry W, Döcke WD.

Arch Dermatol Res. 1997 Oct;289(11):623-30.

PMID:
9444385
11.

Effects of fumaric acid esters on blood-brain barrier tight junction proteins.

Bénardais K, Pul R, Singh V, Skripuletz T, Lee DH, Linker RA, Gudi V, Stangel M.

Neurosci Lett. 2013 Oct 25;555:165-70. doi: 10.1016/j.neulet.2013.09.038. Epub 2013 Sep 26.

PMID:
24076006
12.

Monomethylfumarate induces γ-globin expression and fetal hemoglobin production in cultured human retinal pigment epithelial (RPE) and erythroid cells, and in intact retina.

Promsote W, Makala L, Li B, Smith SB, Singh N, Ganapathy V, Pace BS, Martin PM.

Invest Ophthalmol Vis Sci. 2014 May 13;55(8):5382-93. doi: 10.1167/iovs.14-14179.

13.

Regulation of proton-coupled folate transporter in retinal Müller cells by the antipsoriatic drug monomethylfumarate.

Bozard BR, Chothe PP, Tawfik A, Williams C, Fulzele S, Prasad PD, Martin PM, Ganapathy V, Smith SB.

Glia. 2012 Mar;60(3):333-42. doi: 10.1002/glia.22266. Epub 2011 Nov 9.

14.

Cytokine secretion pattern in treatment of lymphocytes of multiple sclerosis patients with fumaric acid esters.

Zoghi S, Amirghofran Z, Nikseresht A, Ashjazadeh N, Kamali-Sarvestani E, Rezaei N.

Immunol Invest. 2011;40(6):581-96. doi: 10.3109/08820139.2011.569626. Epub 2011 Apr 21.

PMID:
21510778
15.

Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.

Ananth S, Babu E, Veeranan-Karmegam R, Bozard Baldowski BR, Boettger T, Martin PM.

Invest Ophthalmol Vis Sci. 2013 Mar 1;54(3):1592-602. doi: 10.1167/iovs.12-11289.

PMID:
23404113
16.

PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells.

Deng X, Rui W, Zhang F, Ding W.

Cell Biol Toxicol. 2013 Jun;29(3):143-57. doi: 10.1007/s10565-013-9242-5. Epub 2013 Mar 24.

PMID:
23525690
17.

Intracellular signalling by binding sites for the antipsoriatic agent monomethylfumarate on human granulocytes.

Nibbering PH, Thio B, Bezemer AC, Beijersbergen RL, Zomerdijk TP.

Br J Dermatol. 1997 Jul;137(1):65-75.

PMID:
9274627
18.
19.

A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2-ARE pathway: therapeutic implications for ALS.

Kanno T, Tanaka K, Yanagisawa Y, Yasutake K, Hadano S, Yoshii F, Hirayama N, Ikeda JE.

Free Radic Biol Med. 2012 Dec 1;53(11):2028-42. doi: 10.1016/j.freeradbiomed.2012.09.010. Epub 2012 Sep 20.

PMID:
23000247
20.

Glatiramer acetate attenuates the pro-migratory profile of adhesion molecules on various immune cell subsets in multiple sclerosis.

Sellner J, Koczi W, Harrer A, Oppermann K, Obregon-Castrillo E, Pilz G, Wipfler P, Afazel S, Haschke-Becher E, Trinka E, Kraus J.

Clin Exp Immunol. 2013 Sep;173(3):381-9. doi: 10.1111/cei.12125.

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