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Items: 1 to 20 of 112

1.

Preparation and evaluation of a CD13/APN-targeting and hydrolase-resistant conjugate that comprises pingyangmycin and NGR motif-integrated apoprotein.

Li B, Zheng YB, Li DD, Zhen YS.

J Pharm Sci. 2014 Apr;103(4):1204-13. doi: 10.1002/jps.23893. Epub 2014 Feb 6.

PMID:
24504597
2.

An NGR-integrated and enediyne-energized apoprotein shows CD13-targeting antitumor activity.

Zheng YB, Shang BY, Li Y, Zhen YS.

Biomed Pharmacother. 2013 Mar;67(2):164-71. doi: 10.1016/j.biopha.2012.10.018. Epub 2012 Nov 19.

PMID:
23206754
3.

An EGFR/CD13 bispecific fusion protein and its enediyne-energized analog show potent antitumor activity.

Sheng W, Shang Y, Li L, Zhen Y.

Anticancer Drugs. 2014 Jan;25(1):82-91. doi: 10.1097/CAD.0000000000000029.

PMID:
24100279
4.

[Effect of antibody-targeted chemotherapy with pingyangmycin on prostate cancer cells in vitro].

Chen WZ, Zhang Y, Liang CS, Xie Y, Wen QQ, Gao X.

Nan Fang Yi Ke Da Xue Xue Bao. 2008 Mar;28(3):406-8. Chinese.

5.

[Effect of the conjugate composed of a human monoclonal antibody and pingyangmycin on mammary cancer].

Wang WG, Wang SH, Xue YC, Zhen YS.

Yao Xue Xue Bao. 1995;30(8):583-7. Chinese.

PMID:
8571778
6.

A CD13-targeting peptide integrated protein inhibits human liver cancer growth by killing cancer stem cells and suppressing angiogenesis.

Zheng YB, Gong JH, Liu XJ, Li Y, Zhen YS.

Mol Carcinog. 2017 May;56(5):1395-1404. doi: 10.1002/mc.22600. Epub 2017 Jan 4.

PMID:
27991698
7.
8.

Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells.

Curnis F, Arrigoni G, Sacchi A, Fischetti L, Arap W, Pasqualini R, Corti A.

Cancer Res. 2002 Feb 1;62(3):867-74.

9.

[Use of monoclonal antibody-pinyangmycin conjugate in experimental regional targeting therapy of tumor].

Wang WG, Xu LN, Zhang SH, Xue YC, Zhen YS.

Yao Xue Xue Bao. 1997 Sep;32(9):669-74. Chinese.

PMID:
11596291
10.

68Ga-labeled cyclic NGR peptide for microPET imaging of CD13 receptor expression.

Shao Y, Liang W, Kang F, Yang W, Ma X, Li G, Zong S, Chen K, Wang J.

Molecules. 2014 Aug 5;19(8):11600-12. doi: 10.3390/molecules190811600.

11.

In vivo imaging of Aminopeptidase N (CD13) receptors in experimental renal tumors using the novel radiotracer (68)Ga-NOTA-c(NGR).

Máté G, Kertész I, Enyedi KN, Mező G, Angyal J, Vasas N, Kis A, Szabó É, Emri M, Bíró T, Galuska L, Trencsényi G.

Eur J Pharm Sci. 2015 Mar 10;69:61-71. doi: 10.1016/j.ejps.2015.01.002. Epub 2015 Jan 13.

PMID:
25592229
12.

[Preparation of lymphatic targeting dosage form: pingyangmycin absorbed on activated carbon nanoparticles].

Sun ML, Wen YM, Wang CM, Li LJ, Wang XY.

Hua Xi Kou Qiang Yi Xue Za Zhi. 2004 Jun;22(3):183-5. Chinese.

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68Ga-DOTA-NGR as a novel molecular probe for APN-positive tumor imaging using MicroPET.

Zhang J, Lu X, Wan N, Hua Z, Wang Z, Huang H, Yang M, Wang F.

Nucl Med Biol. 2014 Mar;41(3):268-75. doi: 10.1016/j.nucmedbio.2013.12.008. Epub 2013 Dec 18.

PMID:
24438818
17.

Identification of carbonic anhydrase 9 as a contributor to pingyangmycin-induced drug resistance in human tongue cancer cells.

Zheng G, Zhou M, Ou X, Peng B, Yu Y, Kong F, Ouyang Y, He Z.

FEBS J. 2010 Nov;277(21):4506-18. doi: 10.1111/j.1742-4658.2010.07836.x. Epub 2010 Oct 4.

18.

The carbamoylmannose moiety of bleomycin mediates selective tumor cell targeting.

Bhattacharya C, Yu Z, Rishel MJ, Hecht SM.

Biochemistry. 2014 May 27;53(20):3264-6. doi: 10.1021/bi500482q. Epub 2014 May 13.

19.

APN/CD13-targeting as a strategy to alter the tumor accumulation of liposomes.

Dunne M, Zheng J, Rosenblat J, Jaffray DA, Allen C.

J Control Release. 2011 Sep 25;154(3):298-305. doi: 10.1016/j.jconrel.2011.05.022. Epub 2011 May 27.

PMID:
21640146
20.

Pingyangmycin downregulates the expression of EGFR and enhances the effects of cetuximab on esophageal cancer cells and the xenograft in athymic mice.

Gong JH, Liu XJ, Li Y, Zhen YS.

Cancer Chemother Pharmacol. 2012 May;69(5):1323-32. doi: 10.1007/s00280-012-1827-9. Epub 2012 Feb 5.

PMID:
22311160

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