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EIF5A2 predicts outcome in localised invasive bladder cancer and promotes bladder cancer cell aggressiveness in vitro and in vivo.

Wei JH, Cao JZ, Zhang D, Liao B, Zhong WM, Lu J, Zhao HW, Zhang JX, Tong ZT, Fan S, Liang CZ, Liao YB, Pang J, Wu RH, Fang Y, Chen ZH, Li B, Xie D, Chen W, Luo JH.

Br J Cancer. 2014 Apr 2;110(7):1767-77. doi: 10.1038/bjc.2014.52. Epub 2014 Feb 6.


Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial-mesenchymaltransition.

Zhu W, Cai MY, Tong ZT, Dong SS, Mai SJ, Liao YJ, Bian XW, Lin MC, Kung HF, Zeng YX, Guan XY, Xie D.

Gut. 2012 Apr;61(4):562-75. doi: 10.1136/gutjnl-2011-300207. Epub 2011 Aug 3.


Increased expression of EIF5A2, via hypoxia or gene amplification, contributes to metastasis and angiogenesis of esophageal squamous cell carcinoma.

Li Y, Fu L, Li JB, Qin Y, Zeng TT, Zhou J, Zeng ZL, Chen J, Cao TT, Ban X, Qian C, Cai Z, Xie D, Huang P, Guan XY.

Gastroenterology. 2014 Jun;146(7):1701-13.e9. doi: 10.1053/j.gastro.2014.02.029. Epub 2014 Feb 21.


TGF-β-induced upregulation of malat1 promotes bladder cancer metastasis by associating with suz12.

Fan Y, Shen B, Tan M, Mu X, Qin Y, Zhang F, Liu Y.

Clin Cancer Res. 2014 Mar 15;20(6):1531-41. doi: 10.1158/1078-0432.CCR-13-1455. Epub 2014 Jan 21.


Sonic Hedgehog-GLI Family Zinc Finger 1 Signaling Pathway Promotes the Growth and Migration of Pancreatic Cancer Cells by Regulating the Transcription of Eukaryotic Translation Initiation Factor 5A2.

Xu X, Liu H, Zhang H, Dai W, Guo C, Xie C, Wei S, He S, Xu X.

Pancreas. 2015 Nov;44(8):1252-8. doi: 10.1097/MPA.0000000000000532.


Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma.

Tang DJ, Dong SS, Ma NF, Xie D, Chen L, Fu L, Lau SH, Li Y, Li Y, Guan XY.

Hepatology. 2010 Apr;51(4):1255-63. doi: 10.1002/hep.23451.


Fibroblast growth factor receptor splice variants are stable markers of oncogenic transforming growth factor β1 signaling in metastatic breast cancers.

Wendt MK, Taylor MA, Schiemann BJ, Sossey-Alaoui K, Schiemann WP.

Breast Cancer Res. 2014 Mar 11;16(2):R24. doi: 10.1186/bcr3623.


Overexpression of Rab25 contributes to metastasis of bladder cancer through induction of epithelial-mesenchymal transition and activation of Akt/GSK-3β/Snail signaling.

Zhang J, Wei J, Lu J, Tong Z, Liao B, Yu B, Zheng F, Huang X, Chen Z, Fang Y, Li B, Chen W, Xie D, Luo J.

Carcinogenesis. 2013 Oct;34(10):2401-8. doi: 10.1093/carcin/bgt187. Epub 2013 May 30.


Short hairpin RNA targeting FOXQ1 inhibits invasion and metastasis via the reversal of epithelial-mesenchymal transition in bladder cancer.

Zhu Z, Zhu Z, Pang Z, Xing Y, Wan F, Lan D, Wang H.

Int J Oncol. 2013 Apr;42(4):1271-8. doi: 10.3892/ijo.2013.1807. Epub 2013 Feb 5.


Sonic hedgehog (Shh) signaling promotes tumorigenicity and stemness via activation of epithelial-to-mesenchymal transition (EMT) in bladder cancer.

Islam SS, Mokhtari RB, Noman AS, Uddin M, Rahman MZ, Azadi MA, Zlotta A, van der Kwast T, Yeger H, Farhat WA.

Mol Carcinog. 2016 May;55(5):537-51. doi: 10.1002/mc.22300. Epub 2015 Mar 1.


[Effects of eukaryotic translation initiation factor 5A2 down-regulation by small interfering RNA on aggressiveness of MKN28 human].

Meng QB, Yu JC, Kang WM, Ma ZQ, Zhou L, Ye X, Cao ZJ, Tian SB.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2014 Oct;36(5):482-7. doi: 10.3881/j.issn.1000-503X.2014.05.005. Chinese.


Overexpression of eukaryotic translation initiation factor 5A2 (EIF5A2) correlates with cell aggressiveness and poor survival in gastric cancer.

Meng QB, Kang WM, Yu JC, Liu YQ, Ma ZQ, Zhou L, Cui QC, Zhou WX.

PLoS One. 2015 Mar 20;10(3):e0119229. doi: 10.1371/journal.pone.0119229. eCollection 2015.


AIB1 predicts bladder cancer outcome and promotes bladder cancer cell proliferation through AKT and E2F1.

Tong ZT, Wei JH, Zhang JX, Liang CZ, Liao B, Lu J, Fan S, Chen ZH, Zhang F, Ma HH, Qian WC, Kong LL, Fang Y, Chen W, Xie D, Luo JH.

Br J Cancer. 2013 Apr 16;108(7):1470-9. doi: 10.1038/bjc.2013.81. Epub 2013 Mar 19.


1-Methyl-D-tryptophan potentiates TGF-β-induced epithelial-mesenchymal transition in T24 human bladder cancer cells.

Brito RB, Malta CS, Souza DM, Matheus LH, Matos YS, Silva CS, Ferreira JM, Nunes VS, França CM, Dellê H.

PLoS One. 2015 Aug 12;10(8):e0134858. doi: 10.1371/journal.pone.0134858. eCollection 2015.


Downregulation of integrin-linked kinase inhibits epithelial-to-mesenchymal transition and metastasis in bladder cancer cells.

Zhu J, Pan X, Zhang Z, Gao J, Zhang L, Chen J.

Cell Signal. 2012 Jun;24(6):1323-32.


Hepatocyte nuclear factor 6 suppresses the migration and invasive growth of lung cancer cells through p53 and the inhibition of epithelial-mesenchymal transition.

Yuan XW, Wang DM, Hu Y, Tang YN, Shi WW, Guo XJ, Song JG.

J Biol Chem. 2013 Oct 25;288(43):31206-16. doi: 10.1074/jbc.M113.480285. Epub 2013 Sep 10.


Down-regulating ribonuclease inhibitor enhances metastasis of bladder cancer cells through regulating epithelial-mesenchymal transition and ILK signaling pathway.

Xiong D, Liou Y, Shu J, Li D, Zhang L, Chen J.

Exp Mol Pathol. 2014 Jun;96(3):411-21. doi: 10.1016/j.yexmp.2014.04.012. Epub 2014 Apr 24.


Transforming growth factor-β 1 enhances the invasiveness of breast cancer cells by inducing a Smad2-dependent epithelial-to-mesenchymal transition.

Lv ZD, Kong B, Li JG, Qu HL, Wang XG, Cao WH, Liu XY, Wang Y, Yang ZC, Xu HM, Wang HB.

Oncol Rep. 2013 Jan;29(1):219-25. doi: 10.3892/or.2012.2111. Epub 2012 Oct 30.


Epithelial-to-mesenchymal transition markers to predict response of Berberine in suppressing lung cancer invasion and metastasis.

Qi HW, Xin LY, Xu X, Ji XX, Fan LH.

J Transl Med. 2014 Jan 24;12:22. doi: 10.1186/1479-5876-12-22.

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