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Items: 1 to 20 of 55

1.

EMT twists the road to PI3K.

Niederst MJ, Benes CH.

Cancer Discov. 2014 Feb;4(2):149-51. doi: 10.1158/2159-8290.CD-13-1030.

2.

Epithelial-to-mesenchymal transition rewires the molecular path to PI3K-dependent proliferation.

Salt MB, Bandyopadhyay S, McCormick F.

Cancer Discov. 2014 Feb;4(2):186-99. doi: 10.1158/2159-8290.CD-13-0520.

3.

A new role for the PI3K/Akt signaling pathway in the epithelial-mesenchymal transition.

Xu W, Yang Z, Lu N.

Cell Adh Migr. 2015;9(4):317-24. doi: 10.1080/19336918.2015.1016686. Review.

4.

PI3K signalling is required for a TGFβ-induced epithelial-mesenchymal-like transition (EMT-like) in human melanoma cells.

Schlegel NC, von Planta A, Widmer DS, Dummer R, Christofori G.

Exp Dermatol. 2015 Jan;24(1):22-8. doi: 10.1111/exd.12580.

PMID:
25363503
5.

Activation of IL-8 via PI3K/Akt-dependent pathway is involved in leptin-mediated epithelial-mesenchymal transition in human breast cancer cells.

Wang L, Tang C, Cao H, Li K, Pang X, Zhong L, Dang W, Tang H, Huang Y, Wei L, Su M, Chen T.

Cancer Biol Ther. 2015;16(8):1220-30. doi: 10.1080/15384047.2015.1056409.

6.

Junctional adhesion molecule-A, an epithelial-mesenchymal transition inducer, correlates with metastasis and poor prognosis in human nasopharyngeal cancer.

Tian Y, Tian Y, Zhang W, Wei F, Yang J, Luo X, Zhou T, Hou B, Qian S, Deng X, Qiu Y, Yao K.

Carcinogenesis. 2015 Jan;36(1):41-8. doi: 10.1093/carcin/bgu230.

7.
8.

The impact of microRNA-mediated PI3K/AKT signaling on epithelial-mesenchymal transition and cancer stemness in endometrial cancer.

Dong P, Konno Y, Watari H, Hosaka M, Noguchi M, Sakuragi N.

J Transl Med. 2014 Aug 21;12:231. doi: 10.1186/s12967-014-0231-0. Review.

9.

Danusertib Induces Apoptosis, Cell Cycle Arrest, and Autophagy but Inhibits Epithelial to Mesenchymal Transition Involving PI3K/Akt/mTOR Signaling Pathway in Human Ovarian Cancer Cells.

Zi D, Zhou ZW, Yang YJ, Huang L, Zhou ZL, He SM, He ZX, Zhou SF.

Int J Mol Sci. 2015 Nov 13;16(11):27228-51. doi: 10.3390/ijms161126018.

10.

An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.

Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV.

Clin Cancer Res. 2013 Jan 1;19(1):279-90. doi: 10.1158/1078-0432.CCR-12-1558.

11.

EMT Transition Alters Interstitial Fluid Flow-Induced Signaling in ERBB2-Positive Breast Cancer Cells.

Tchafa AM, Ta M, Reginato MJ, Shieh AC.

Mol Cancer Res. 2015 Apr;13(4):755-64. doi: 10.1158/1541-7786.MCR-14-0471.

12.

Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways.

Chen XF, Zhang HJ, Wang HB, Zhu J, Zhou WY, Zhang H, Zhao MC, Su JM, Gao W, Zhang L, Fei K, Zhang HT, Wang HY.

Mol Biol Rep. 2012 Apr;39(4):3549-56. doi: 10.1007/s11033-011-1128-0.

PMID:
21713404
13.

Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells.

Choi JH, Hwang YP, Kim HG, Khanal T, Do MT, Jin SW, Han HJ, Lee HS, Lee YC, Chung YC, Jeong TC, Jeong HG.

Nutr Cancer. 2014;66(1):140-51. doi: 10.1080/01635581.2014.853087.

PMID:
24341702
14.

FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion.

Gardberg M, Kaipio K, Lehtinen L, Mikkonen P, Heuser VD, Talvinen K, Iljin K, Kampf C, Uhlen M, Grénman R, Koivisto M, Carpén O.

PLoS One. 2013 Sep 26;8(9):e74923. doi: 10.1371/journal.pone.0074923.

15.

Osthole inhibits insulin-like growth factor-1-induced epithelial to mesenchymal transition via the inhibition of PI3K/Akt signaling pathway in human brain cancer cells.

Lin YC, Lin JC, Hung CM, Chen Y, Liu LC, Chang TC, Kao JY, Ho CT, Way TD.

J Agric Food Chem. 2014 Jun 4;62(22):5061-71. doi: 10.1021/jf501047g.

PMID:
24828835
16.

Curcumin suppresses doxorubicin-induced epithelial-mesenchymal transition via the inhibition of TGF-β and PI3K/AKT signaling pathways in triple-negative breast cancer cells.

Chen WC, Lai YA, Lin YC, Ma JW, Huang LF, Yang NS, Ho CT, Kuo SC, Way TD.

J Agric Food Chem. 2013 Dec 4;61(48):11817-24. doi: 10.1021/jf404092f.

PMID:
24236784
17.

Lack of estrogen receptor-α is associated with epithelial-mesenchymal transition and PI3K alterations in endometrial carcinoma.

Wik E, Ræder MB, Krakstad C, Trovik J, Birkeland E, Hoivik EA, Mjos S, Werner HM, Mannelqvist M, Stefansson IM, Oyan AM, Kalland KH, Akslen LA, Salvesen HB.

Clin Cancer Res. 2013 Mar 1;19(5):1094-105. doi: 10.1158/1078-0432.CCR-12-3039.

18.

Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells.

Suman S, Kurisetty V, Das TP, Vadodkar A, Ramos G, Lakshmanaswamy R, Damodaran C.

Mol Carcinog. 2014 Feb;53 Suppl 1:E151-60. doi: 10.1002/mc.22076.

PMID:
24000138
19.

Epithelial Mesenchymal Transition in Aggressive Lung Cancers.

Mittal V.

Adv Exp Med Biol. 2016;890:37-56. doi: 10.1007/978-3-319-24932-2_3. Review.

PMID:
26703798
20.

PI3K, Erk signaling in BMP7-induced epithelial-mesenchymal transition (EMT) of PC-3 prostate cancer cells in 2- and 3-dimensional cultures.

Lim M, Chuong CM, Roy-Burman P.

Horm Cancer. 2011 Oct;2(5):298-309. doi: 10.1007/s12672-011-0084-4.

PMID:
21948155
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