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Items: 1 to 20 of 177

1.

A GNAS mutation found in pancreatic intraductal papillary mucinous neoplasms induces drastic alterations of gene expression profiles with upregulation of mucin genes.

Komatsu H, Tanji E, Sakata N, Aoki T, Motoi F, Naitoh T, Katayose Y, Egawa S, Unno M, Furukawa T.

PLoS One. 2014 Feb 3;9(2):e87875. doi: 10.1371/journal.pone.0087875. eCollection 2014.

2.

GNAS mutation is a frequent event in pancreatic intraductal papillary mucinous neoplasms and associated adenocarcinomas.

Hosoda W, Sasaki E, Murakami Y, Yamao K, Shimizu Y, Yatabe Y.

Virchows Arch. 2015 Jun;466(6):665-74. doi: 10.1007/s00428-015-1751-6. Epub 2015 Mar 22.

PMID:
25796395
3.

Intraductal papillary mucinous neoplasms of the pancreas with distinct pancreatic ductal adenocarcinomas are frequently of gastric subtype.

Ideno N, Ohtsuka T, Kono H, Fujiwara K, Oda Y, Aishima S, Ito T, Ishigami K, Tokunaga S, Ohuchida K, Takahata S, Nakamura M, Mizumoto K, Tanaka M.

Ann Surg. 2013 Jul;258(1):141-51. doi: 10.1097/SLA.0b013e31828cd008.

PMID:
23532108
4.

GNAS and KRAS Mutations Define Separate Progression Pathways in Intraductal Papillary Mucinous Neoplasm-Associated Carcinoma.

Tan MC, Basturk O, Brannon AR, Bhanot U, Scott SN, Bouvier N, LaFemina J, Jarnagin WR, Berger MF, Klimstra D, Allen PJ.

J Am Coll Surg. 2015 May;220(5):845-854.e1. doi: 10.1016/j.jamcollsurg.2014.11.029. Epub 2015 Feb 11.

5.

Deep sequencing of cancer-related genes revealed GNAS mutations to be associated with intraductal papillary mucinous neoplasms and its main pancreatic duct dilation.

Takano S, Fukasawa M, Maekawa S, Kadokura M, Miura M, Shindo H, Takahashi E, Sato T, Enomoto N.

PLoS One. 2014 Jun 4;9(6):e98718. doi: 10.1371/journal.pone.0098718. eCollection 2014.

6.

Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas.

Molin MD, Matthaei H, Wu J, Blackford A, Debeljak M, Rezaee N, Wolfgang CL, Butturini G, Salvia R, Bassi C, Goggins MG, Kinzler KW, Vogelstein B, Eshleman JR, Hruban RH, Maitra A.

Ann Surg Oncol. 2013 Nov;20(12):3802-8. doi: 10.1245/s10434-013-3096-1. Epub 2013 Jul 12.

7.

GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "incipient IPMNs".

Matthaei H, Wu J, Dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Kalff JC, Wolfgang CL, Kinzler KW, Vogelstein B, Maitra A, Hruban RH.

Am J Surg Pathol. 2014 Mar;38(3):360-3. doi: 10.1097/PAS.0000000000000117.

8.

The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant.

Yamaguchi H, Kuboki Y, Hatori T, Yamamoto M, Shimizu K, Shiratori K, Shibata N, Shimizu M, Furukawa T.

J Pathol. 2013 Nov;231(3):335-41. doi: 10.1002/path.4242.

PMID:
23893889
9.

Preoperative GNAS and KRAS testing in the diagnosis of pancreatic mucinous cysts.

Singhi AD, Nikiforova MN, Fasanella KE, McGrath KM, Pai RK, Ohori NP, Bartholow TL, Brand RE, Chennat JS, Lu X, Papachristou GI, Slivka A, Zeh HJ, Zureikat AH, Lee KK, Tsung A, Mantha GS, Khalid A.

Clin Cancer Res. 2014 Aug 15;20(16):4381-9. doi: 10.1158/1078-0432.CCR-14-0513. Epub 2014 Jun 17.

10.

Clinical significance of GNAS mutation in intraductal papillary mucinous neoplasm of the pancreas with concomitant pancreatic ductal adenocarcinoma.

Ideno N, Ohtsuka T, Matsunaga T, Kimura H, Watanabe Y, Tamura K, Aso T, Aishima S, Miyasaka Y, Ohuchida K, Ueda J, Takahata S, Oda Y, Mizumoto K, Tanaka M.

Pancreas. 2015 Mar;44(2):311-20. doi: 10.1097/MPA.0000000000000258.

PMID:
25479586
11.

Distinction of Invasive Carcinoma Derived From Intraductal Papillary Mucinous Neoplasms From Concomitant Ductal Adenocarcinoma of the Pancreas Using Molecular Biomarkers.

Tamura K, Ohtsuka T, Date K, Fujimoto T, Matsunaga T, Kimura H, Watanabe Y, Miyazaki T, Ohuchida K, Takahata S, Ishigami K, Oda Y, Mizumoto K, Nakamura M, Tanaka M.

Pancreas. 2016 Jul;45(6):826-35. doi: 10.1097/MPA.0000000000000563.

PMID:
26646266
12.

Targeted next-generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas.

Amato E, Molin MD, Mafficini A, Yu J, Malleo G, Rusev B, Fassan M, Antonello D, Sadakari Y, Castelli P, Zamboni G, Maitra A, Salvia R, Hruban RH, Bassi C, Capelli P, Lawlor RT, Goggins M, Scarpa A.

J Pathol. 2014 Jul;233(3):217-27. doi: 10.1002/path.4344.

13.

Lessons from McCune-Albright syndrome-associated intraductal papillary mucinous neoplasms: : GNAS-activating mutations in pancreatic carcinogenesis.

Parvanescu A, Cros J, Ronot M, Hentic O, Grybek V, Couvelard A, Levy P, Chanson P, Ruszniewski P, Sauvanet A, Gaujoux S.

JAMA Surg. 2014 Aug;149(8):858-62. doi: 10.1001/jamasurg.2014.535.

PMID:
24898823
14.

Tracking the Clonal Evolution of Adenosquamous Carcinoma, a Rare Variant of Intraductal Papillary Mucinous Neoplasm of the Pancreas.

Matsuzaka S, Karasaki H, Ono Y, Ogata M, Oikawa K, Tamakawa S, Chiba S, Muraki M, Yokochi T, Funakoshi H, Kono T, Nagashima K, Mizukami Y.

Pancreas. 2016 Jul;45(6):915-8. doi: 10.1097/MPA.0000000000000556.

PMID:
27295533
15.

GNAS(R201H) and Kras(G12D) cooperate to promote murine pancreatic tumorigenesis recapitulating human intraductal papillary mucinous neoplasm.

Taki K, Ohmuraya M, Tanji E, Komatsu H, Hashimoto D, Semba K, Araki K, Kawaguchi Y, Baba H, Furukawa T.

Oncogene. 2016 May 5;35(18):2407-12. doi: 10.1038/onc.2015.294. Epub 2015 Aug 10.

PMID:
26257060
16.

Mucin gene expression in intraductal papillary-mucinous pancreatic tumours and related lesions.

Terris B, Dubois S, Buisine MP, Sauvanet A, Ruszniewski P, Aubert JP, Porchet N, Couvelard A, Degott C, Fléjou JF.

J Pathol. 2002 Aug;197(5):632-7.

PMID:
12210083
17.

Assessment of clonality of multisegmental main duct intraductal papillary mucinous neoplasms of the pancreas based on GNAS mutation analysis.

Tamura K, Ohtsuka T, Matsunaga T, Kimura H, Watanabe Y, Ideno N, Aso T, Miyazaki T, Ohuchida K, Takahata S, Ito T, Ushijima Y, Oda Y, Mizumoto K, Tanaka M.

Surgery. 2015 Feb;157(2):277-84. doi: 10.1016/j.surg.2014.09.013. Epub 2014 Dec 16.

PMID:
25530484
18.

Genome-wide CpG island profiling of intraductal papillary mucinous neoplasms of the pancreas.

Hong SM, Omura N, Vincent A, Li A, Knight S, Yu J, Hruban RH, Goggins M.

Clin Cancer Res. 2012 Feb 1;18(3):700-12. doi: 10.1158/1078-0432.CCR-11-1718. Epub 2011 Dec 15.

19.

Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas.

Furukawa T, Kuboki Y, Tanji E, Yoshida S, Hatori T, Yamamoto M, Shibata N, Shimizu K, Kamatani N, Shiratori K.

Sci Rep. 2011;1:161. doi: 10.1038/srep00161. Epub 2011 Nov 18.

20.

RNF43 mutation frequently occurs with GNAS mutation and mucin hypersecretion in intraductal papillary neoplasms of the bile duct.

Tsai JH, Liau JY, Yuan CT, Cheng ML, Yuan RH, Jeng YM.

Histopathology. 2017 Apr;70(5):756-765. doi: 10.1111/his.13125. Epub 2017 Jan 10.

PMID:
27864998

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