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Items: 1 to 20 of 137

1.

A targeted RNA interference screen reveals novel epigenetic factors that regulate herpesviral gene expression.

Oh HS, Bryant KF, Nieland TJ, Mazumder A, Bagul M, Bathe M, Root DE, Knipe DM.

MBio. 2014 Feb 4;5(1):e01086-13. doi: 10.1128/mBio.01086-13.

2.

A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency.

Liang Y, Quenelle D, Vogel JL, Mascaro C, Ortega A, Kristie TM.

MBio. 2013 Feb 5;4(1):e00558-12. doi: 10.1128/mBio.00558-12.

3.

Cellular Transcriptional Coactivator RanBP10 and Herpes Simplex Virus 1 ICP0 Interact and Synergistically Promote Viral Gene Expression and Replication.

Sato Y, Kato A, Maruzuru Y, Oyama M, Kozuka-Hata H, Arii J, Kawaguchi Y.

J Virol. 2016 Jan 6;90(6):3173-86. doi: 10.1128/JVI.03043-15.

4.

Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells.

Hancock MH, Cliffe AR, Knipe DM, Smiley JR.

J Virol. 2010 Feb;84(3):1366-75. doi: 10.1128/JVI.01727-09. Epub 2009 Nov 25.

6.

Herpes simplex virus regulatory proteins VP16 and ICP0 counteract an innate intranuclear barrier to viral gene expression.

Hancock MH, Corcoran JA, Smiley JR.

Virology. 2006 Aug 15;352(1):237-52. Epub 2006 Jun 5.

7.

Impaired STING Pathway in Human Osteosarcoma U2OS Cells Contributes to the Growth of ICP0-Null Mutant Herpes Simplex Virus.

Deschamps T, Kalamvoki M.

J Virol. 2017 Apr 13;91(9). pii: e00006-17. doi: 10.1128/JVI.00006-17. Print 2017 May 1.

PMID:
28179534
8.

Epigenetic repression of herpes simplex virus infection by the nucleosome remodeler CHD3.

Arbuckle JH, Kristie TM.

MBio. 2014 Jan 14;5(1):e01027-13. doi: 10.1128/mBio.01027-13.

9.

Herpesviral ICP0 Protein Promotes Two Waves of Heterochromatin Removal on an Early Viral Promoter during Lytic Infection.

Lee JS, Raja P, Knipe DM.

MBio. 2016 Jan 12;7(1):e02007-15. doi: 10.1128/mBio.02007-15.

10.
11.

The Nuclear DNA Sensor IFI16 Acts as a Restriction Factor for Human Papillomavirus Replication through Epigenetic Modifications of the Viral Promoters.

Lo Cigno I, De Andrea M, Borgogna C, Albertini S, Landini MM, Peretti A, Johnson KE, Chandran B, Landolfo S, Gariglio M.

J Virol. 2015 Aug;89(15):7506-20. doi: 10.1128/JVI.00013-15. Epub 2015 May 13.

12.

Dynamic modulation of HSV chromatin drives initiation of infection and provides targets for epigenetic therapies.

Kristie TM.

Virology. 2015 May;479-480:555-61. doi: 10.1016/j.virol.2015.01.026. Epub 2015 Feb 18. Review.

13.

Role of ND10 nuclear bodies in the chromatin repression of HSV-1.

Gu H, Zheng Y.

Virol J. 2016 Apr 5;13:62. doi: 10.1186/s12985-016-0516-4. Review.

14.

Inhibition of O-Linked N-Acetylglucosamine Transferase Reduces Replication of Herpes Simplex Virus and Human Cytomegalovirus.

Angelova M, Ortiz-Meoz RF, Walker S, Knipe DM.

J Virol. 2015 Aug;89(16):8474-83. doi: 10.1128/JVI.01002-15. Epub 2015 Jun 3.

15.

Epigenetic modulation of gene expression from quiescent herpes simplex virus genomes.

Ferenczy MW, DeLuca NA.

J Virol. 2009 Sep;83(17):8514-24. doi: 10.1128/JVI.00785-09. Epub 2009 Jun 17.

16.

Cellular SNF2H chromatin-remodeling factor promotes herpes simplex virus 1 immediate-early gene expression and replication.

Bryant KF, Colgrove RC, Knipe DM.

MBio. 2011 Jan 18;2(1):e00330-10. doi: 10.1128/mBio.00330-10.

17.

Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunity.

Knipe DM.

Virology. 2015 May;479-480:153-9. doi: 10.1016/j.virol.2015.02.009. Epub 2015 Mar 3. Review.

18.

IFI16 restricts HSV-1 replication by accumulating on the hsv-1 genome, repressing HSV-1 gene expression, and directly or indirectly modulating histone modifications.

Johnson KE, Bottero V, Flaherty S, Dutta S, Singh VV, Chandran B.

PLoS Pathog. 2014 Nov 6;10(11):e1004503. doi: 10.1371/journal.ppat.1004503. eCollection 2014 Nov.

19.

De novo synthesis of VP16 coordinates the exit from HSV latency in vivo.

Thompson RL, Preston CM, Sawtell NM.

PLoS Pathog. 2009 Mar;5(3):e1000352. doi: 10.1371/journal.ppat.1000352. Epub 2009 Mar 27.

20.

Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency.

Liang Y, Vogel JL, Arbuckle JH, Rai G, Jadhav A, Simeonov A, Maloney DJ, Kristie TM.

Sci Transl Med. 2013 Jan 9;5(167):167ra5. doi: 10.1126/scitranslmed.3005145.

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