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Items: 1 to 20 of 104

1.

Andrographolide, a Novel NF- κ B Inhibitor, Induces Vascular Smooth Muscle Cell Apoptosis via a Ceramide-p47phox-ROS Signaling Cascade.

Chen YY, Hsu MJ, Sheu JR, Lee LW, Hsieh CY.

Evid Based Complement Alternat Med. 2013;2013:821813. doi: 10.1155/2013/821813. Epub 2013 Dec 29.

2.

Andrographolide inhibits nuclear factor-κB activation through JNK-Akt-p65 signaling cascade in tumor necrosis factor-α-stimulated vascular smooth muscle cells.

Chen YY, Hsu MJ, Hsieh CY, Lee LW, Chen ZC, Sheu JR.

ScientificWorldJournal. 2014;2014:130381. doi: 10.1155/2014/130381. Epub 2014 Jul 10.

3.

Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade.

Chen YY, Hsieh CY, Jayakumar T, Lin KH, Chou DS, Lu WJ, Hsu MJ, Sheu JR.

Sci Rep. 2014 Jul 10;4:5651. doi: 10.1038/srep05651.

4.

Andrographolide enhances nuclear factor-kappaB subunit p65 Ser536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells.

Hsieh CY, Hsu MJ, Hsiao G, Wang YH, Huang CW, Chen SW, Jayakumar T, Chiu PT, Chiu YH, Sheu JR.

J Biol Chem. 2011 Feb 25;286(8):5942-55. doi: 10.1074/jbc.M110.123968. Epub 2010 Dec 17.

5.

Mitochondrial-mediated apoptosis in lymphoma cells by the diterpenoid lactone andrographolide, the active component of Andrographis paniculata.

Yang S, Evens AM, Prachand S, Singh AT, Bhalla S, David K, Gordon LI.

Clin Cancer Res. 2010 Oct 1;16(19):4755-68. doi: 10.1158/1078-0432.CCR-10-0883. Epub 2010 Aug 26.

6.

Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis.

Reinehr R, Becker S, Eberle A, Grether-Beck S, Häussinger D.

J Biol Chem. 2005 Jul 22;280(29):27179-94. Epub 2005 May 25.

7.
8.

PMC, a potent hydrophilic α-tocopherol derivative, inhibits NF-κB activation via PP2A but not IκBα-dependent signals in vascular smooth muscle cells.

Hsieh CY, Hsiao G, Hsu MJ, Wang YH, Sheu JR.

J Cell Mol Med. 2014 Jul;18(7):1278-89. doi: 10.1111/jcmm.12277. Epub 2014 Apr 13.

9.

Suppression of NF-κB signaling by andrographolide with a novel mechanism in human platelets: regulatory roles of the p38 MAPK-hydroxyl radical-ERK2 cascade.

Lu WJ, Lin KH, Hsu MJ, Chou DS, Hsiao G, Sheu JR.

Biochem Pharmacol. 2012 Oct 1;84(7):914-24. doi: 10.1016/j.bcp.2012.06.030. Epub 2012 Jul 4.

PMID:
22771630
10.

Mechanical stretch enhances mRNA expression and proenzyme release of matrix metalloproteinase-2 (MMP-2) via NAD(P)H oxidase-derived reactive oxygen species.

Grote K, Flach I, Luchtefeld M, Akin E, Holland SM, Drexler H, Schieffer B.

Circ Res. 2003 Jun 13;92(11):e80-6. Epub 2003 May 15.

11.

Homocysteine enhances cell proliferation in vascular smooth muscle cells: role of p38 MAPK and p47phox.

Zou T, Yang W, Hou Z, Yang J.

Acta Biochim Biophys Sin (Shanghai). 2010 Dec;42(12):908-15. doi: 10.1093/abbs/gmq102. Epub 2010 Nov 10.

PMID:
21068125
13.

Lysophosphatidylcholine activates extracellular signal-regulated kinases 1/2 through reactive oxygen species in rat vascular smooth muscle cells.

Yamakawa T, Tanaka S, Yamakawa Y, Kamei J, Numaguchi K, Motley ED, Inagami T, Eguchi S.

Arterioscler Thromb Vasc Biol. 2002 May 1;22(5):752-8.

14.
15.

Vaspin attenuates high glucose-induced vascular smooth muscle cells proliferation and chemokinesis by inhibiting the MAPK, PI3K/Akt, and NF-κB signaling pathways.

Li H, Peng W, Zhuang J, Lu Y, Jian W, Wei Y, Li W, Xu Y.

Atherosclerosis. 2013 May;228(1):61-8. doi: 10.1016/j.atherosclerosis.2013.02.013. Epub 2013 Feb 27.

PMID:
23497782
16.

Andrographolide induces apoptosis in B16F-10 melanoma cells by inhibiting NF-κB-mediated bcl-2 activation and modulating p53-induced caspase-3 gene expression.

Pratheeshkumar P, Sheeja K, Kuttan G.

Immunopharmacol Immunotoxicol. 2012 Feb;34(1):143-51. doi: 10.3109/08923973.2011.588233. Epub 2011 Jun 20.

PMID:
21682651
17.

Cyclophilin A is required for angiotensin II-induced p47phox translocation to caveolae in vascular smooth muscle cells.

Soe NN, Sowden M, Baskaran P, Smolock EM, Kim Y, Nigro P, Berk BC.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2147-53. doi: 10.1161/ATVBAHA.113.301894. Epub 2013 Jul 11.

18.

Effects of Panax notoginseng saponins on proliferation and apoptosis of vascular smooth muscle cells.

Xu L, Liu JT, Liu N, Lu PP, Pang XM.

J Ethnopharmacol. 2011 Sep 1;137(1):226-30. doi: 10.1016/j.jep.2011.05.020. Epub 2011 May 17.

PMID:
21619919
19.

Ceramide mediates Ox-LDL-induced human vascular smooth muscle cell calcification via p38 mitogen-activated protein kinase signaling.

Liao L, Zhou Q, Song Y, Wu W, Yu H, Wang S, Chen Y, Ye M, Lu L.

PLoS One. 2013 Dec 16;8(12):e82379. doi: 10.1371/journal.pone.0082379. eCollection 2013.

20.

BRCA1 shields vascular smooth muscle cells from oxidative stress.

Lovren F, Pan Y, Quan A, Singh KK, Khan R, Gupta N, Brezden-Masley C, Teoh H, Wheatcroft MD, Al-Omran M, Verma S.

J Thorac Cardiovasc Surg. 2014 Jun;147(6):1946-55, 1955.e1. doi: 10.1016/j.jtcvs.2013.09.060. Epub 2013 Nov 13.

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