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Items: 1 to 20 of 239

1.

EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.

Miao H, Gale NW, Guo H, Qian J, Petty A, Kaspar J, Murphy AJ, Valenzuela DM, Yancopoulos G, Hambardzumyan D, Lathia JD, Rich JN, Lee J, Wang B.

Oncogene. 2015 Jan 29;34(5):558-67. doi: 10.1038/onc.2013.590. Epub 2014 Feb 3.

2.

A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion.

Gopal U, Bohonowych JE, Lema-Tome C, Liu A, Garrett-Mayer E, Wang B, Isaacs JS.

PLoS One. 2011 Mar 8;6(3):e17649. doi: 10.1371/journal.pone.0017649.

3.

Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells.

Wakimoto H, Mohapatra G, Kanai R, Curry WT Jr, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD.

Neuro Oncol. 2012 Feb;14(2):132-44. doi: 10.1093/neuonc/nor195. Epub 2011 Nov 7.

4.

MET signaling regulates glioblastoma stem cells.

Joo KM, Jin J, Kim E, Ho Kim K, Kim Y, Gu Kang B, Kang YJ, Lathia JD, Cheong KH, Song PH, Kim H, Seol HJ, Kong DS, Lee JI, Rich JN, Lee J, Nam DH.

Cancer Res. 2012 Aug 1;72(15):3828-38. Epub 2012 May 22.

5.

Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity.

Sun P, Xia S, Lal B, Shi X, Yang KS, Watkins PA, Laterra J.

BMC Cancer. 2014 Jun 4;14:401. doi: 10.1186/1471-2407-14-401.

6.

EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt.

Miao H, Li DQ, Mukherjee A, Guo H, Petty A, Cutter J, Basilion JP, Sedor J, Wu J, Danielpour D, Sloan AE, Cohen ML, Wang B.

Cancer Cell. 2009 Jul 7;16(1):9-20. doi: 10.1016/j.ccr.2009.04.009.

7.

MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1.

Bier A, Giladi N, Kronfeld N, Lee HK, Cazacu S, Finniss S, Xiang C, Poisson L, deCarvalho AC, Slavin S, Jacoby E, Yalon M, Toren A, Mikkelsen T, Brodie C.

Oncotarget. 2013 May;4(5):665-76.

8.

MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.

Joshi K, Banasavadi-Siddegowda Y, Mo X, Kim SH, Mao P, Kig C, Nardini D, Sobol RW, Chow LM, Kornblum HI, Waclaw R, Beullens M, Nakano I.

Stem Cells. 2013 Jun;31(6):1051-63. doi: 10.1002/stem.1358.

9.

LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program.

Mao XG, Hütt-Cabezas M, Orr BA, Weingart M, Taylor I, Rajan AK, Odia Y, Kahlert U, Maciaczyk J, Nikkhah G, Eberhart CG, Raabe EH.

Oncotarget. 2013 Jul;4(7):1050-64.

10.

Myelin-forming cell-specific cadherin-19 is a marker for minimally infiltrative glioblastoma stem-like cells.

Zorniak M, Clark PA, Kuo JS.

J Neurosurg. 2015 Jan;122(1):69-77. doi: 10.3171/2014.9.JNS132373.

11.

FoxM1 Promotes Stemness and Radio-Resistance of Glioblastoma by Regulating the Master Stem Cell Regulator Sox2.

Lee Y, Kim KH, Kim DG, Cho HJ, Kim Y, Rheey J, Shin K, Seo YJ, Choi YS, Lee JI, Lee J, Joo KM, Nam DH.

PLoS One. 2015 Oct 7;10(10):e0137703. doi: 10.1371/journal.pone.0137703. eCollection 2015.

12.

Neurotensin signaling regulates stem-like traits of glioblastoma stem cells through activation of IL-8/CXCR1/STAT3 pathway.

Zhou J, Yi L, Ouyang Q, Xu L, Cui H, Xu M.

Cell Signal. 2014 Dec;26(12):2896-902. doi: 10.1016/j.cellsig.2014.08.027. Epub 2014 Sep 6.

PMID:
25200966
13.

The EphA2 receptor drives self-renewal and tumorigenicity in stem-like tumor-propagating cells from human glioblastomas.

Binda E, Visioli A, Giani F, Lamorte G, Copetti M, Pitter KL, Huse JT, Cajola L, Zanetti N, DiMeco F, De Filippis L, Mangiola A, Maira G, Anile C, De Bonis P, Reynolds BA, Pasquale EB, Vescovi AL.

Cancer Cell. 2012 Dec 11;22(6):765-80. doi: 10.1016/j.ccr.2012.11.005.

14.

The LIM-only transcription factor LMO2 determines tumorigenic and angiogenic traits in glioma stem cells.

Kim SH, Kim EJ, Hitomi M, Oh SY, Jin X, Jeon HM, Beck S, Jin X, Kim JK, Park CG, Chang SY, Yin J, Kim T, Jeon YJ, Song J, Lim YC, Lathia JD, Nakano I, Kim H.

Cell Death Differ. 2015 Sep;22(9):1517-25. doi: 10.1038/cdd.2015.7. Epub 2015 Feb 27.

15.

A new 2-pyrone derivative, 5-bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2-one, suppresses stemness in glioma stem-like cells.

Kim RK, Kim MJ, Yoon CH, Lim EJ, Yoo KC, Lee GH, Kim YH, Kim H, Jin YB, Lee YJ, Cho CG, Oh YS, Gye MC, Suh Y, Lee SJ.

Mol Pharmacol. 2012 Sep;82(3):400-7. doi: 10.1124/mol.112.078402. Epub 2012 May 30.

16.

Cytomegalovirus Immediate-Early Proteins Promote Stemness Properties in Glioblastoma.

Soroceanu L, Matlaf L, Khan S, Akhavan A, Singer E, Bezrookove V, Decker S, Ghanny S, Hadaczek P, Bengtsson H, Ohlfest J, Luciani-Torres MG, Harkins L, Perry A, Guo H, Soteropoulos P, Cobbs CS.

Cancer Res. 2015 Aug 1;75(15):3065-76. doi: 10.1158/0008-5472.CAN-14-3307.

17.

Molecular heterogeneity in a patient-derived glioblastoma xenoline is regulated by different cancer stem cell populations.

Garner JM, Ellison DW, Finkelstein D, Ganguly D, Du Z, Sims M, Yang CH, Interiano RB, Davidoff AM, Pfeffer LM.

PLoS One. 2015 May 8;10(5):e0125838. doi: 10.1371/journal.pone.0125838. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0145052.

18.

Invasive glioblastoma cells acquire stemness and increased Akt activation.

Molina JR, Hayashi Y, Stephens C, Georgescu MM.

Neoplasia. 2010 Jun;12(6):453-63.

19.

The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells.

Koyama-Nasu R, Haruta R, Nasu-Nishimura Y, Taniue K, Katou Y, Shirahige K, Todo T, Ino Y, Mukasa A, Saito N, Matsui M, Takahashi R, Hoshino-Okubo A, Sugano H, Manabe E, Funato K, Akiyama T.

Oncogene. 2014 Apr 24;33(17):2236-44. doi: 10.1038/onc.2013.168. Epub 2013 May 20.

PMID:
23686309
20.

Increased level of H19 long noncoding RNA promotes invasion, angiogenesis, and stemness of glioblastoma cells.

Jiang X, Yan Y, Hu M, Chen X, Wang Y, Dai Y, Wu D, Wang Y, Zhuang Z, Xia H.

J Neurosurg. 2016 Jan;124(1):129-36. doi: 10.3171/2014.12.JNS1426. Epub 2015 Aug 14.

PMID:
26274999

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