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Items: 1 to 20 of 170

1.

4'-Substituted pyrimidine nucleosides lacking 5'-hydroxyl function as potential anti-HCV agents.

Shakya N, Vedi S, Liang C, Yang F, Agrawal B, Kumar R.

Bioorg Med Chem Lett. 2014 Mar 1;24(5):1407-9. doi: 10.1016/j.bmcl.2014.01.024. Epub 2014 Jan 17.

PMID:
24485784
2.

A new class of pyrimidine nucleosides: inhibitors of hepatitis B and C viruses.

Shakya N, Vedi S, Liang C, Agrawal B, Tyrrell DL, Kumar R.

Bioorg Med Chem Lett. 2012 Oct 15;22(20):6475-80. doi: 10.1016/j.bmcl.2012.08.042. Epub 2012 Aug 21.

PMID:
22985854
3.

Synthesis and anti-hepatitis C virus (HCV) activity of 3'-C-substituted-methyl pyrimidine and purine nucleosides.

Choi WJ, Kim YM, Kim HO, Lee HW, Kim DE, Park KS, Chong Y, Jeong LS.

Bioorg Med Chem. 2010 Jul 1;18(13):4812-20. doi: 10.1016/j.bmc.2010.05.002. Epub 2010 May 31.

PMID:
20627592
4.

Synthesis of 2'-fluoro and 2',4'-dimethyl pyrimidine C-nucleoside analogues as potential anti-HCV agents.

Liu LJ, Hong JH.

Nucleosides Nucleotides Nucleic Acids. 2010 Mar;29(3):216-27. doi: 10.1080/15257771003705617.

PMID:
20408052
5.
6.

Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents.

Pei X, Choi WJ, Kim YM, Zhao LX, Jeong LS.

Arch Pharm Res. 2008 Jul;31(7):843-9. doi: 10.1007/s12272-001-1236-z. Epub 2008 Aug 14.

PMID:
18704325
7.

Inhibition of hepatitis B virus (HBV) replication by pyrimidines bearing an acyclic moiety: effect on wild-type and mutant HBV.

Semaine W, Johar M, Tyrrell DL, Kumar R, Agrawal B.

J Med Chem. 2006 Mar 23;49(6):2049-54.

PMID:
16539393
8.

Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors.

Mish MR, Cho A, Kirschberg T, Xu J, Zonte CS, Fenaux M, Park Y, Babusis D, Feng JY, Ray AS, Kim CU.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3092-5. doi: 10.1016/j.bmcl.2014.05.015. Epub 2014 May 22.

PMID:
24907145
9.

[New furano- and pyrrolo[2,3-d]pyrimidine nucleosides and their 5'-triphosphates: synthesis and biological properties].

Ivanov MA, Ivanov AV, Krasnitskaia IA, Smirnova OA, Karpenko IL, Belanov EF, Prasolov VS, Tunitskaia VL, Aleksandrova LA.

Bioorg Khim. 2008 Sep-Oct;34(5):661-70. Russian.

PMID:
19060941
10.

[Bicyclic furano[2,3-D] derivatives of pyrimidine nucleosides--synthesis and antiviral properties].

Ivanov MA, Aleksandrova LA.

Bioorg Khim. 2013 Jan-Feb;39(1):26-45. Review. Russian.

PMID:
23844505
11.

Anti-hepatitis C virus activity of novel beta-d-2'-C-methyl-4'-azido pyrimidine nucleoside phosphoramidate prodrugs.

Rondla R, Coats SJ, McBrayer TR, Grier J, Johns M, Tharnish PM, Whitaker T, Zhou L, Schinazi RF.

Antivir Chem Chemother. 2009 Oct 19;20(2):99-106. doi: 10.3851/IMP1400.

PMID:
19843980
12.

Synthesis and antiviral evaluation of 4'-C-azidomethyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides.

Griffon JF, Dumas A, Storer R, Sommadossi JP, Gosselin G.

Nucleosides Nucleotides Nucleic Acids. 2009 May;28(5):435-49. doi: 10.1080/15257770903044531.

PMID:
20183594
13.

Studies on the anti-hepatitis C virus activity of newly synthesized tropolone derivatives: identification of NS3 helicase inhibitors that specifically inhibit subgenomic HCV replication.

Najda-Bernatowicz A, Krawczyk M, Stankiewicz-Drogoń A, Bretner M, Boguszewska-Chachulska AM.

Bioorg Med Chem. 2010 Jul 15;18(14):5129-36. doi: 10.1016/j.bmc.2010.05.066. Epub 2010 Jun 2.

PMID:
20579888
14.
16.

Synthesis and hepatitis C antiviral activity of 1-aminobenzyl-1H-indazole-3-carboxamide analogues.

Shi JJ, Ji FH, He PL, Yang YX, Tang W, Zuo JP, Li YC.

ChemMedChem. 2013 May;8(5):722-5. doi: 10.1002/cmdc.201300083. Epub 2013 Mar 19.

PMID:
23512654
17.

Synthesis and characterization of 1'-C-cyano-2'-fluoro-2'-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.

Kirschberg TA, Mish MR, Zhang L, Squires NH, Wang KY, Cho A, Feng JY, Fenaux M, Babusis D, Park Y, Ray AS, Kim CU.

Bioorg Med Chem Lett. 2015 Mar 1;25(5):1040-3. doi: 10.1016/j.bmcl.2015.01.021. Epub 2015 Jan 17.

PMID:
25650256
18.

Novel 5-vinyl pyrimidine nucleosides with potent anti-hepatitis B virus activity.

Kumar R, Tyrrell DL.

Bioorg Med Chem Lett. 2001 Nov 19;11(22):2917-20.

PMID:
11677126
19.

Discovery and characterization of substituted diphenyl heterocyclic compounds as potent and selective inhibitors of hepatitis C virus replication.

Huang P, Goff DA, Huang Q, Martinez A, Xu X, Crowder S, Issakani SD, Anderson E, Sheng N, Achacoso P, Yen A, Kinsella T, Darwish IS, Kolluri R, Hong H, Qu K, Stauffer E, Goldstein E, Singh R, Payan DG, Lu HH.

Antimicrob Agents Chemother. 2008 Apr;52(4):1419-29. doi: 10.1128/AAC.00525-07. Epub 2008 Jan 28.

PMID:
18227176
20.

Synthesis and anti-HSV activity of new N1-acyclic C4 and C6-disubstituted pyrazolo[3,4-d]pyrimidine nucleosides.

Moukha-chafiq O, Taha ML, Mouna A.

Nucleosides Nucleotides Nucleic Acids. 2007;26(8-9):1107-10.

PMID:
18058546

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