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Items: 1 to 20 of 67

1.

Progeria: a paradigm for translational medicine.

Gordon LB, Rothman FG, López-Otín C, Misteli T.

Cell. 2014 Jan 30;156(3):400-7. doi: 10.1016/j.cell.2013.12.028.

2.

Medicine. Mouse study suggests cancer drugs could help prematurely aging kids.

Travis J.

Science. 2006 Feb 17;311(5763):934-5. No abstract available.

PMID:
16484462
3.

Cardiovascular insights from a premature aging syndrome: a translational story.

Nabel EG.

Trans Am Clin Climatol Assoc. 2012;123:221-5; discussion 225-6.

4.

A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.

Fong LG, Frost D, Meta M, Qiao X, Yang SH, Coffinier C, Young SG.

Science. 2006 Mar 17;311(5767):1621-3. Epub 2006 Feb 16.

5.

Rejuvenating premature aging.

Meshorer E, Gruenbaum Y.

Nat Med. 2008 Jul;14(7):713-5. doi: 10.1038/nm0708-713. No abstract available.

PMID:
18607367
6.

A-type lamins and Hutchinson-Gilford progeria syndrome: pathogenesis and therapy.

Gonzalez JM, Pla D, Perez-Sala D, Andres V.

Front Biosci (Schol Ed). 2011 Jun 1;3:1133-46. Review.

PMID:
21622261
7.

Ageing: rushed decisions.

Shadan S.

Nature. 2008 Mar 6;452(7183):39. doi: 10.1038/452039a. No abstract available.

PMID:
18322520
8.

Progeria, the nucleolus and farnesyltransferase inhibitors.

Mehta IS, Bridger JM, Kill IR.

Biochem Soc Trans. 2010 Feb;38(Pt 1):287-91. doi: 10.1042/BST0380287.

PMID:
20074076
9.

Hutchinson-Gilford progeria syndrome, cardiovascular disease and oxidative stress.

Trigueros-Motos L, Gonzalez JM, Rivera J, Andres V.

Front Biosci (Schol Ed). 2011 Jun 1;3:1285-97. Review.

PMID:
21622271
10.

Lamin A-linked progerias: is farnesylation the be all and end all?

Smallwood DT, Shackleton S.

Biochem Soc Trans. 2010 Feb;38(Pt 1):281-6. doi: 10.1042/BST0380281.

PMID:
20074075
11.

[A-type lamins and progeroïd syndromes : persistent farnesylation with dramatic effects].

Navarro CL, Poitelon Y, Lévy N.

Med Sci (Paris). 2008 Oct;24(10):833-40. doi: 10.1051/medsci/20082410833. Review. French.

12.

Does progeria provide the best model of accelerated ageing in humans?

Mills RG, Weiss AS.

Gerontology. 1990;36(2):84-98.

PMID:
2376331
13.

[Could progeria be a model for the natural process of aging?].

Herman WA, łacka K.

Pol Merkur Lekarski. 2005 Jan;18(103):5-8. Review. Polish.

PMID:
15859537
14.

ZMPSTE24, an integral membrane zinc metalloprotease with a connection to progeroid disorders.

Barrowman J, Michaelis S.

Biol Chem. 2009 Aug;390(8):761-73. doi: 10.1515/BC.2009.080. Review.

PMID:
19453269
15.

Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science.

Gordon LB, Harling-Berg CJ, Rothman FG.

J Gerontol A Biol Sci Med Sci. 2008 Aug;63(8):777-87. No abstract available.

PMID:
18772465
16.

Embryonic senescence and laminopathies in a progeroid zebrafish model.

Koshimizu E, Imamura S, Qi J, Toure J, Valdez DM Jr, Carr CE, Hanai J, Kishi S.

PLoS One. 2011 Mar 30;6(3):e17688. doi: 10.1371/journal.pone.0017688.

17.

Targeting protein prenylation in progeria.

Young SG, Yang SH, Davies BS, Jung HJ, Fong LG.

Sci Transl Med. 2013 Feb 6;5(171):171ps3. doi: 10.1126/scitranslmed.3005229. Review.

18.

Prelamin A prenylation and the treatment of progeria.

Worman HJ.

J Lipid Res. 2010 Feb;51(2):223-5. doi: 10.1194/jlr.E004366. Epub 2009 Nov 25. No abstract available.

19.

N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A.

Bifulco M, D'Alessandro A, Paladino S, Malfitano AM, Notarnicola M, Caruso MG, Laezza C.

FEBS J. 2013 Dec;280(23):6223-32. doi: 10.1111/febs.12544. Epub 2013 Nov 18.

20.

Hutchinson-Gilford progeria syndrome through the lens of transcription.

Prokocimer M, Barkan R, Gruenbaum Y.

Aging Cell. 2013 Aug;12(4):533-43. doi: 10.1111/acel.12070. Epub 2013 Apr 19. Review.

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