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Items: 1 to 20 of 303

1.

Characterization of a novel acetamidobenzoxazolone-based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain.

Tiwari AK, Yui J, Fujinaga M, Kumata K, Shimoda Y, Yamasaki T, Xie L, Hatori A, Maeda J, Nengaki N, Zhang MR.

J Neurochem. 2014 May;129(4):712-20. doi: 10.1111/jnc.12670. Epub 2014 Feb 24.

2.

Synthesis and evaluation of new (18)F-labelled acetamidobenzoxazolone-based radioligands for imaging of the translocator protein (18 kDa, TSPO) in the brain.

Tiwari AK, Fujinaga M, Yui J, Yamasaki T, Xie L, Kumata K, Mishra AK, Shimoda Y, Hatori A, Ji B, Ogawa M, Kawamura K, Wang F, Zhang MR.

Org Biomol Chem. 2014 Dec 21;12(47):9621-30. doi: 10.1039/c4ob01933d. Epub 2014 Oct 23.

PMID:
25339090
3.

[18F]FEBMP: Positron Emission Tomography Imaging of TSPO in a Model of Neuroinflammation in Rats, and in vitro Autoradiograms of the Human Brain.

Tiwari AK, Ji B, Yui J, Fujinaga M, Yamasaki T, Xie L, Luo R, Shimoda Y, Kumata K, Zhang Y, Hatori A, Maeda J, Higuchi M, Wang F, Zhang MR.

Theranostics. 2015 May 26;5(9):961-9. doi: 10.7150/thno.12027. eCollection 2015.

4.

18F-FEAC and 18F-FEDAC: PET of the monkey brain and imaging of translocator protein (18 kDa) in the infarcted rat brain.

Yui J, Maeda J, Kumata K, Kawamura K, Yanamoto K, Hatori A, Yamasaki T, Nengaki N, Higuchi M, Zhang MR.

J Nucl Med. 2010 Aug;51(8):1301-9. doi: 10.2967/jnumed.109.072223. Epub 2010 Jul 21.

5.

Radiosynthesis and in vivo evaluation of two imidazopyridineacetamides, [(11)C]CB184 and [ (11)C]CB190, as a PET tracer for 18 kDa translocator protein: direct comparison with [ (11)C](R)-PK11195.

Hatano K, Sekimata K, Yamada T, Abe J, Ito K, Ogawa M, Magata Y, Toyohara J, Ishiwata K, Biggio G, Serra M, Laquintana V, Denora N, Latrofa A, Trapani G, Liso G, Suzuki H, Sawada M, Nomura M, Toyama H.

Ann Nucl Med. 2015 May;29(4):325-35. doi: 10.1007/s12149-015-0948-8. Epub 2015 Jan 24.

6.

11C-AC-5216: a novel PET ligand for peripheral benzodiazepine receptors in the primate brain.

Zhang MR, Kumata K, Maeda J, Yanamoto K, Hatori A, Okada M, Higuchi M, Obayashi S, Suhara T, Suzuki K.

J Nucl Med. 2007 Nov;48(11):1853-61.

7.

Comparative evaluation of the translocator protein radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a rat model of acute neuroinflammation.

Chauveau F, Van Camp N, Dollé F, Kuhnast B, Hinnen F, Damont A, Boutin H, James M, Kassiou M, Tavitian B.

J Nucl Med. 2009 Mar;50(3):468-76. doi: 10.2967/jnumed.108.058669. Epub 2009 Feb 17.

8.

Visualization of early infarction in rat brain after ischemia using a translocator protein (18 kDa) PET ligand [11C]DAC with ultra-high specific activity.

Yui J, Hatori A, Kawamura K, Yanamoto K, Yamasaki T, Ogawa M, Yoshida Y, Kumata K, Fujinaga M, Nengaki N, Fukumura T, Suzuki K, Zhang MR.

Neuroimage. 2011 Jan 1;54(1):123-30. doi: 10.1016/j.neuroimage.2010.08.010. Epub 2010 Aug 10.

PMID:
20705143
9.

Evaluation of N-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.

Yanamoto K, Yamasaki T, Kumata K, Yui J, Odawara C, Kawamura K, Hatori A, Inoue O, Yamaguchi M, Suzuki K, Zhang MR.

Synapse. 2009 Nov;63(11):961-71. doi: 10.1002/syn.20678.

PMID:
19593823
10.

The translocator protein ligand [¹⁸F]DPA-714 images glioma and activated microglia in vivo.

Winkeler A, Boisgard R, Awde AR, Dubois A, Thézé B, Zheng J, Ciobanu L, Dollé F, Viel T, Jacobs AH, Tavitian B.

Eur J Nucl Med Mol Imaging. 2012 May;39(5):811-23. doi: 10.1007/s00259-011-2041-4. Epub 2012 Jan 21.

11.

[(11)C]DAC-PET for noninvasively monitoring neuroinflammation and immunosuppressive therapy efficacy in rat experimental autoimmune encephalomyelitis model.

Xie L, Yamasaki T, Ichimaru N, Yui J, Kawamura K, Kumata K, Hatori A, Nonomura N, Zhang MR, Li XK, Takahara S.

J Neuroimmune Pharmacol. 2012 Mar;7(1):231-42. doi: 10.1007/s11481-011-9322-3. Epub 2011 Oct 29.

PMID:
22038158
12.

Exploration of the impact of stereochemistry on the identification of the novel translocator protein PET imaging agent [(18)F]GE-180.

Chau WF, Black AM, Clarke A, Durrant C, Gausemel I, Khan I, Mantzilas D, Oulie I, Rogstad A, Trigg W, Jones PA.

Nucl Med Biol. 2015 Sep;42(9):711-9. doi: 10.1016/j.nucmedbio.2015.05.004. Epub 2015 May 27.

13.

Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia.

Martín A, Boisgard R, Thézé B, Van Camp N, Kuhnast B, Damont A, Kassiou M, Dollé F, Tavitian B.

J Cereb Blood Flow Metab. 2010 Jan;30(1):230-41. doi: 10.1038/jcbfm.2009.205. Epub 2009 Sep 30.

14.

Radiosynthesis and preclinical evaluation of 11C-ABP688 as a probe for imaging the metabotropic glutamate receptor subtype 5.

Ametamey SM, Kessler LJ, Honer M, Wyss MT, Buck A, Hintermann S, Auberson YP, Gasparini F, Schubiger PA.

J Nucl Med. 2006 Apr;47(4):698-705.

15.

18F-GE-180: a novel TSPO radiotracer compared to 11C-R-PK11195 in a preclinical model of stroke.

Boutin H, Murray K, Pradillo J, Maroy R, Smigova A, Gerhard A, Jones PA, Trigg W.

Eur J Nucl Med Mol Imaging. 2015 Mar;42(3):503-11. doi: 10.1007/s00259-014-2939-8. Epub 2014 Oct 29.

PMID:
25351507
16.

Comparison of in vivo binding properties of the 18-kDa translocator protein (TSPO) ligands [(18)F]PBR102 and [ (18)F]PBR111 in a model of excitotoxin-induced neuroinflammation.

Callaghan PD, Wimberley CA, Rahardjo GL, Berghofer PJ, Pham TQ, Jackson T, Zahra D, Bourdier T, Wyatt N, Greguric I, Howell NR, Siegele R, Pastuovic Z, Mattner F, Loc'h C, Gregoire MC, Katsifis A.

Eur J Nucl Med Mol Imaging. 2015 Jan;42(1):138-51. doi: 10.1007/s00259-014-2895-3. Epub 2014 Sep 18.

PMID:
25231248
17.

Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.

Price CJ, Wang D, Menon DK, Guadagno JV, Cleij M, Fryer T, Aigbirhio F, Baron JC, Warburton EA.

Stroke. 2006 Jul;37(7):1749-53. Epub 2006 Jun 8.

18.

Novel Pyrazolo[1,5-a]pyrimidines as Translocator Protein 18 kDa (TSPO) Ligands: Synthesis, in Vitro Biological Evaluation, [(18)F]-Labeling, and in Vivo Neuroinflammation PET Images.

Damont A, Médran-Navarrete V, Cacheux F, Kuhnast B, Pottier G, Bernards N, Marguet F, Puech F, Boisgard R, Dollé F.

J Med Chem. 2015 Sep 24;58(18):7449-64. doi: 10.1021/acs.jmedchem.5b00932. Epub 2015 Sep 3.

PMID:
26280386
19.

In vivo imaging and characterization of [(18)F]DPA-714, a potential new TSPO ligand, in mouse brain and peripheral tissues using small-animal PET.

Vicidomini C, Panico M, Greco A, Gargiulo S, Coda AR, Zannetti A, Gramanzini M, Roviello GN, Quarantelli M, Alfano B, Tavitian B, Dollé F, Salvatore M, Brunetti A, Pappatà S.

Nucl Med Biol. 2015 Mar;42(3):309-16. doi: 10.1016/j.nucmedbio.2014.11.009. Epub 2014 Dec 6.

PMID:
25537727
20.

Synthesis of [¹¹C]PBR170, a novel imidazopyridine, for imaging the translocator protein with PET.

Bourdier T, Henderson D, Fookes CJ, Lam P, Mattner F, Fulham M, Katsifis A.

Appl Radiat Isot. 2014 Aug;90:46-52. doi: 10.1016/j.apradiso.2014.03.009. Epub 2014 Mar 18.

PMID:
24685494

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