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Items: 1 to 20 of 107

1.

Histone deacetylase inhibitors valproic acid and sodium butyrate enhance prostaglandins release in lipopolysaccharide-activated primary microglia.

Singh V, Bhatia HS, Kumar A, de Oliveira AC, Fiebich BL.

Neuroscience. 2014 Apr 18;265:147-57. doi: 10.1016/j.neuroscience.2014.01.037. Epub 2014 Jan 28.

PMID:
24480366
2.

Activated microglia decrease histone acetylation and Nrf2-inducible anti-oxidant defence in astrocytes: restoring effects of inhibitors of HDACs, p38 MAPK and GSK3β.

Correa F, Mallard C, Nilsson M, Sandberg M.

Neurobiol Dis. 2011 Oct;44(1):142-51. doi: 10.1016/j.nbd.2011.06.016. Epub 2011 Jul 2.

3.

A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons.

Fujiki R, Sato A, Fujitani M, Yamashita T.

Cell Death Dis. 2013 Jun 20;4:e677. doi: 10.1038/cddis.2013.205.

4.

Histone deacetylase inhibitors suppress immune activation in primary mouse microglia.

Kannan V, Brouwer N, Hanisch UK, Regen T, Eggen BJ, Boddeke HW.

J Neurosci Res. 2013 Sep;91(9):1133-42. doi: 10.1002/jnr.23221. Epub 2013 May 17.

PMID:
23686642
5.

Valproic acid attenuates microgliosis in injured spinal cord and purinergic P2X4 receptor expression in activated microglia.

Lu WH, Wang CY, Chen PS, Wang JW, Chuang DM, Yang CS, Tzeng SF.

J Neurosci Res. 2013 May;91(5):694-705. doi: 10.1002/jnr.23200. Epub 2013 Feb 13.

PMID:
23404572
6.

Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation.

Zhang Z, Qin X, Tong N, Zhao X, Gong Y, Shi Y, Wu X.

Exp Eye Res. 2012 Jan;94(1):98-108. doi: 10.1016/j.exer.2011.11.013. Epub 2011 Nov 28.

PMID:
22143029
7.

Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and DeltaFosB expression in the striatum and locomotor sensitization in mice.

Shen HY, Kalda A, Yu L, Ferrara J, Zhu J, Chen JF.

Neuroscience. 2008 Dec 2;157(3):644-55. doi: 10.1016/j.neuroscience.2008.09.019. Epub 2008 Sep 16.

PMID:
18848971
8.

Regulation of microglial inflammatory response by histone deacetylase inhibitors.

Suuronen T, Huuskonen J, Pihlaja R, Kyrylenko S, Salminen A.

J Neurochem. 2003 Oct;87(2):407-16.

9.

Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity.

Chen PS, Wang CC, Bortner CD, Peng GS, Wu X, Pang H, Lu RB, Gean PW, Chuang DM, Hong JS.

Neuroscience. 2007 Oct 12;149(1):203-12. Epub 2007 Jul 28.

10.

Signal transduction pathways regulating cyclooxygenase-2 in lipopolysaccharide-activated primary rat microglia.

Akundi RS, Candelario-Jalil E, Hess S, Hüll M, Lieb K, Gebicke-Haerter PJ, Fiebich BL.

Glia. 2005 Aug 15;51(3):199-208.

PMID:
15800925
11.

Increased replication of human cytomegalovirus in retinal pigment epithelial cells by valproic acid depends on histone deacetylase inhibition.

Michaelis M, Suhan T, Reinisch A, Reisenauer A, Fleckenstein C, Eikel D, Gümbel H, Doerr HW, Nau H, Cinatl J Jr.

Invest Ophthalmol Vis Sci. 2005 Sep;46(9):3451-7.

PMID:
16123451
12.

Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism.

Takuma K, Hara Y, Kataoka S, Kawanai T, Maeda Y, Watanabe R, Takano E, Hayata-Takano A, Hashimoto H, Ago Y, Matsuda T.

Pharmacol Biochem Behav. 2014 Nov;126:43-9. doi: 10.1016/j.pbb.2014.08.013. Epub 2014 Sep 18.

PMID:
25240644
13.
14.

Valproic acid suppresses lipopolysaccharide-induced cyclooxygenase-2 expression via MKP-1 in murine brain microvascular endothelial cells.

Chuang YF, Yang HY, Ko TL, Hsu YF, Sheu JR, Ou G, Hsu MJ.

Biochem Pharmacol. 2014 Apr 1;88(3):372-83. doi: 10.1016/j.bcp.2014.02.004. Epub 2014 Feb 16.

PMID:
24552656
15.

Release of prostaglandin E(2) and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase.

Matsui T, Svensson CI, Hirata Y, Mizobata K, Hua XY, Yaksh TL.

Anesth Analg. 2010 Aug;111(2):554-60. doi: 10.1213/ANE.0b013e3181e3a2a2. Epub 2010 Jul 7.

PMID:
20610553
16.

Valproic acid exhibits biphasic effects on apoptotic cell death of activated lymphocytes through differential modulation of multiple signaling pathways.

Chen Q, Ouyang DY, Geng M, Xu LH, Zhang YT, Wang FP, He XH.

J Immunotoxicol. 2011 Jul-Sep;8(3):210-8. doi: 10.3109/1547691X.2011.568979. Epub 2011 Apr 4.

PMID:
21457087
17.

Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation.

Sinn DI, Kim SJ, Chu K, Jung KH, Lee ST, Song EC, Kim JM, Park DK, Kun Lee S, Kim M, Roh JK.

Neurobiol Dis. 2007 May;26(2):464-72. Epub 2007 Feb 23.

PMID:
17398106
18.

HDAC inhibitors dysregulate neural stem cell activity in the postnatal mouse brain.

Foti SB, Chou A, Moll AD, Roskams AJ.

Int J Dev Neurosci. 2013 Oct;31(6):434-47. doi: 10.1016/j.ijdevneu.2013.03.008. Epub 2013 Mar 27.

PMID:
23542004
19.

Histone deacetylase inhibitors promote osteoblast maturation.

Schroeder TM, Westendorf JJ.

J Bone Miner Res. 2005 Dec;20(12):2254-63. Epub 2005 Aug 8.

20.

Lipopolysaccharide prevents valproic acid-induced apoptosis via activation of nuclear factor-κB and inhibition of p53 activation.

Tsolmongyn B, Koide N, Odkhuu E, Haque A, Naiki Y, Komatsu T, Yoshida T, Yokochi T.

Cell Immunol. 2013 Apr;282(2):100-5. doi: 10.1016/j.cellimm.2013.04.011. Epub 2013 May 4.

PMID:
23770718

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