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Items: 1 to 20 of 187

1.

Evaluation of a novel series of fluorine-18-labeled imidazobenzodiazepines as potential new positron emission tomography radioligands for the GABAA receptor.

Jackson A, Battle MR, O'Shea DM, Chau WF, Gaeta A, Brown SL, Ewan AL, Jones CL, Jones PA, Woodcraft JL, Bouvet DR, Guilbert BB, Trigg W.

Nucl Med Biol. 2014 Feb;41(2):196-202. doi: 10.1016/j.nucmedbio.2013.11.010. Epub 2013 Dec 7.

PMID:
24480268
2.

Novel fluorine-18 PET radiotracers based on flumazenil for GABAA imaging in the brain.

Rodnick ME, Hockley BG, Sherman P, Quesada C, Battle MR, Jackson A, Linder KE, Macholl S, Trigg WJ, Kilbourn MR, Scott PJ.

Nucl Med Biol. 2013 Oct;40(7):901-5. doi: 10.1016/j.nucmedbio.2013.06.004. Epub 2013 Jul 23.

3.

Biological evaluation of 2'-[18F]fluoroflumazenil ([18F]FFMZ), a potential GABA receptor ligand for PET.

Mitterhauser M, Wadsak W, Wabnegger L, Mien LK, Tögel S, Langer O, Sieghart W, Viernstein H, Kletter K, Dudczak R.

Nucl Med Biol. 2004 Feb;31(2):291-5.

PMID:
15013496
4.

Exploration of the impact of stereochemistry on the identification of the novel translocator protein PET imaging agent [(18)F]GE-180.

Chau WF, Black AM, Clarke A, Durrant C, Gausemel I, Khan I, Mantzilas D, Oulie I, Rogstad A, Trigg W, Jones PA.

Nucl Med Biol. 2015 Sep;42(9):711-9. doi: 10.1016/j.nucmedbio.2015.05.004. Epub 2015 May 27.

5.

The development of potential new fluorine-18 labelled radiotracers for imaging the GABA(A) receptor.

Jackson A, Guilbert BB, Plant SD, Goggi J, Battle MR, Woodcraft JL, Gaeta A, Jones CL, Bouvet DR, Jones PA, O'Shea DM, Zheng PH, Brown SL, Ewan AL, Trigg W.

Bioorg Med Chem Lett. 2013 Feb 1;23(3):821-6. doi: 10.1016/j.bmcl.2012.11.066. Epub 2012 Nov 28.

PMID:
23265897
6.

Development of new radiopharmaceuticals for imaging monoamine oxidase B.

Vasdev N, Sadovski O, Moran MD, Parkes J, Meyer JH, Houle S, Wilson AA.

Nucl Med Biol. 2011 Oct;38(7):933-43. doi: 10.1016/j.nucmedbio.2011.03.003. Epub 2011 Jun 17.

PMID:
21982565
7.

Radiosynthesis and biological evaluation of an 18F-labeled derivative of the novel pyrazolopyrimidine sedative-hypnotic agent indiplon.

Hoepping A, Scheunemann M, Fischer S, Deuther-Conrad W, Hiller A, Wegner F, Diekers M, Steinbach J, Brust P.

Nucl Med Biol. 2007 Jul;34(5):559-70. Epub 2007 Jun 8.

PMID:
17591556
9.

Imidazenil: a new partial positive allosteric modulator of gamma-aminobutyric acid (GABA) action at GABAA receptors.

Giusti P, Ducić I, Puia G, Arban R, Walser A, Guidotti A, Costa E.

J Pharmacol Exp Ther. 1993 Aug;266(2):1018-28.

PMID:
8394902
10.

Synthesis and evaluation of candidate PET radioligands for corticotropin-releasing factor type-1 receptors.

Lodge NJ, Li YW, Chin FT, Dischino DD, Zoghbi SS, Deskus JA, Mattson RJ, Imaizumi M, Pieschl R, Molski TF, Fujita M, Dulac H, Zaczek R, Bronson JJ, Macor JE, Innis RB, Pike VW.

Nucl Med Biol. 2014 Jul;41(6):524-35. doi: 10.1016/j.nucmedbio.2014.03.005. Epub 2014 Mar 29.

11.

Synthesis and radiopharmacological evaluation of a high-affinity and metabolically stabilized 18F-labeled bombesin analogue for molecular imaging of gastrin-releasing peptide receptor-expressing prostate cancer.

Richter S, Wuest M, Krieger SS, Rogers BE, Friebe M, Bergmann R, Wuest F.

Nucl Med Biol. 2013 Nov;40(8):1025-34. doi: 10.1016/j.nucmedbio.2013.07.005. Epub 2013 Aug 19.

PMID:
23969085
12.

Fluorine-18 click radiosynthesis and preclinical evaluation of a new 18F-labeled folic acid derivative.

Ross TL, Honer M, Lam PY, Mindt TL, Groehn V, Schibli R, Schubiger PA, Ametamey SM.

Bioconjug Chem. 2008 Dec;19(12):2462-70. doi: 10.1021/bc800356r.

PMID:
19053298
13.

Development of new carbon-11 labelled radiotracers for imaging GABAA- and GABAB-benzodiazepine receptors.

Moran MD, Wilson AA, Elmore CS, Parkes J, Ng A, Sadovski O, Graff A, Daskalakis ZJ, Houle S, Chapdelaine MJ, Vasdev N.

Bioorg Med Chem. 2012 Jul 15;20(14):4482-8. doi: 10.1016/j.bmc.2012.05.046. Epub 2012 May 24.

PMID:
22717238
14.

[18F]flumazenil binding to central benzodiazepine receptor studies by PET--quantitative analysis and comparisons with [11C]flumazenil.

Odano I, Halldin C, Karlsson P, Varrone A, Airaksinen AJ, Krasikova RN, Farde L.

Neuroimage. 2009 Apr 15;45(3):891-902. doi: 10.1016/j.neuroimage.2008.12.005. Epub 2008 Dec 24.

PMID:
19136064
15.

Syntheses and in vitro evaluation of fluorinated naphthoxazines as dopamine D2/D3 receptor agonists: radiosynthesis, ex vivo biodistribution and autoradiography of [(18)F]F-PHNO.

Vasdev N, Seeman P, Garcia A, Stableford WT, Nobrega JN, Houle S, Wilson AA.

Nucl Med Biol. 2007 Feb;34(2):195-203. Epub 2007 Jan 17.

PMID:
17307127
16.

Synthesis and biological evaluation of carbon-11 and fluorine-18 labeled tracers for in vivo visualization of PDE10A.

Ooms M, Celen S, Koole M, Langlois X, Schmidt M, De Angelis M, Andrés JI, Verbruggen A, Van Laere K, Bormans G.

Nucl Med Biol. 2014 Sep;41(8):695-704. doi: 10.1016/j.nucmedbio.2014.05.138. Epub 2014 May 24.

PMID:
25002365
17.

Fluorine-18 labeling and biodistribution studies on peroxisome proliferator-activated receptor-gamma ligands: potential positron emission tomography imaging agents.

Lee BC, Dence CS, Zhou H, Parent EE, Welch MJ, Katzenellenbogen JA.

Nucl Med Biol. 2009 Feb;36(2):147-53. doi: 10.1016/j.nucmedbio.2008.11.002.

18.

Awake nonhuman primate brain PET imaging with minimal head restraint: evaluation of GABAA-benzodiazepine binding with 11C-flumazenil in awake and anesthetized animals.

Sandiego CM, Jin X, Mulnix T, Fowles K, Labaree D, Ropchan J, Huang Y, Cosgrove K, Castner SA, Williams GV, Wells L, Rabiner EA, Carson RE.

J Nucl Med. 2013 Nov;54(11):1962-8. doi: 10.2967/jnumed.113.122077. Epub 2013 Oct 10.

19.

Single-step radiosynthesis and in vivo evaluation of a novel fluorine-18 labeled hippurate for use as a PET renal agent.

Pathuri G, Hedrick AF, Awasthi V, Gali H.

Nucl Med Biol. 2012 Nov;39(8):1195-201. doi: 10.1016/j.nucmedbio.2012.07.002. Epub 2012 Aug 13.

PMID:
22898317
20.

PET radioligands targeting the brain GABAA /benzodiazepine receptor complex.

Andersson JD, Halldin C.

J Labelled Comp Radiopharm. 2013 Mar-Apr;56(3-4):196-206. doi: 10.1002/jlcr.3008. Review.

PMID:
24285326

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