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Platelet-activating factor contributes to Bacillus anthracis lethal toxin-associated damage.

Rivera J, Sellers RS, Zeng W, van Rooijen N, Casadevall A, Goldman DL.

J Biol Chem. 2014 Mar 7;289(10):7131-41. doi: 10.1074/jbc.M113.524900. Epub 2014 Jan 29.


Lethal toxin actions and their consequences.

Hanna P.

J Appl Microbiol. 1999 Aug;87(2):285-7.


New insights into the pathogenesis and treatment of anthrax toxin-induced shock.

Li Y, Sherer K, Cui X, Eichacker PQ.

Expert Opin Biol Ther. 2007 Jun;7(6):843-54. Review.


Lethal factor, but not edema factor, is required to cause fatal anthrax in cynomolgus macaques after pulmonary spore challenge.

Hutt JA, Lovchik JA, Drysdale M, Sherwood RL, Brasel T, Lipscomb MF, Lyons CR.

Am J Pathol. 2014 Dec;184(12):3205-16. doi: 10.1016/j.ajpath.2014.08.008. Epub 2014 Oct 5.


Contribution of lethal toxin and edema toxin to the pathogenesis of anthrax meningitis.

Ebrahimi CM, Sheen TR, Renken CW, Gottlieb RA, Doran KS.

Infect Immun. 2011 Jul;79(7):2510-8. doi: 10.1128/IAI.00006-11. Epub 2011 Apr 25.


Bacillus anthracis edema and lethal toxin have different hemodynamic effects but function together to worsen shock and outcome in a rat model.

Cui X, Li Y, Li X, Laird MW, Subramanian M, Moayeri M, Leppla SH, Fitz Y, Su J, Sherer K, Eichacker PQ.

J Infect Dis. 2007 Feb 15;195(4):572-80. Epub 2007 Jan 3.


Murine innate immune response to virulent toxigenic and nontoxigenic Bacillus anthracis strains.

Drysdale M, Olson G, Koehler TM, Lipscomb MF, Lyons CR.

Infect Immun. 2007 Apr;75(4):1757-64. Epub 2007 Jan 22.


Lethal and edema toxins in the pathogenesis of Bacillus anthracis septic shock: implications for therapy.

Sherer K, Li Y, Cui X, Eichacker PQ.

Am J Respir Crit Care Med. 2007 Feb 1;175(3):211-21. Epub 2006 Nov 9. Review.


Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.

Bromberg-White J, Lee CS, Duesbery N.

Toxins (Basel). 2010 May;2(5):1038-53. doi: 10.3390/toxins2051038. Epub 2010 May 11. Review.


New insights into the functions of anthrax toxin.

Banks DJ, Ward SC, Bradley KA.

Expert Rev Mol Med. 2006 Apr 11;8(7):1-18. Review.


Bacillus anthracis genomic DNA enhances lethal toxin-induced cytotoxicity through TNF-α production.

Jeon JH, Kim YH, Choi MK, Kim KA, Lee HR, Jang J, Kim YR, Chun JH, Eo SK, Kim TS, Rhie GE.

BMC Microbiol. 2014 Dec 4;14:300. doi: 10.1186/s12866-014-0300-9.


Anthrax toxin targeting of myeloid cells through the CMG2 receptor is essential for establishment of Bacillus anthracis infections in mice.

Liu S, Miller-Randolph S, Crown D, Moayeri M, Sastalla I, Okugawa S, Leppla SH.

Cell Host Microbe. 2010 Nov 18;8(5):455-62. doi: 10.1016/j.chom.2010.10.004.


Anthrax and the inflammasome.

Moayeri M, Sastalla I, Leppla SH.

Microbes Infect. 2012 May;14(5):392-400. doi: 10.1016/j.micinf.2011.12.005. Epub 2011 Dec 17. Review.


Early interactions between fully virulent Bacillus anthracis and macrophages that influence the balance between spore clearance and development of a lethal infection.

Cote CK, DiMezzo TL, Banks DJ, France B, Bradley KA, Welkos SL.

Microbes Infect. 2008 May;10(6):613-9. doi: 10.1016/j.micinf.2008.02.006. Epub 2008 Feb 21.


Dehydroepiandrosterone and melatonin prevent Bacillus anthracis lethal toxin-induced TNF production in macrophages.

Shin S, Hur GH, Kim YB, Yeon GB, Park KJ, Park YM, Lee WS.

Cell Biol Toxicol. 2000;16(3):165-74.


New insights into the biological effects of anthrax toxins: linking cellular to organismal responses.

Guichard A, Nizet V, Bier E.

Microbes Infect. 2012 Feb;14(2):97-118. doi: 10.1016/j.micinf.2011.08.016. Epub 2011 Sep 8. Review.


Cellular and systemic effects of anthrax lethal toxin and edema toxin.

Moayeri M, Leppla SH.

Mol Aspects Med. 2009 Dec;30(6):439-55. doi: 10.1016/j.mam.2009.07.003. Epub 2009 Jul 26. Review.


Proteasome inhibitors prevent caspase-1-mediated disease in rodents challenged with anthrax lethal toxin.

Muehlbauer SM, Lima H Jr, Goldman DL, Jacobson LS, Rivera J, Goldberg MF, Palladino MA, Casadevall A, Brojatsch J.

Am J Pathol. 2010 Aug;177(2):735-43. doi: 10.2353/ajpath.2010.090828. Epub 2010 Jul 1. Erratum in: Am J Pathol. 2010 Oct;177(4):2145.


Exogenous gamma and alpha/beta interferon rescues human macrophages from cell death induced by Bacillus anthracis.

Gold JA, Hoshino Y, Hoshino S, Jones MB, Nolan A, Weiden MD.

Infect Immun. 2004 Mar;72(3):1291-7.

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