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Items: 1 to 20 of 123

1.

Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy.

Cerase A, Smeets D, Tang YA, Gdula M, Kraus F, Spivakov M, Moindrot B, Leleu M, Tattermusch A, Demmerle J, Nesterova TB, Green C, Otte AP, Schermelleh L, Brockdorff N.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2235-40. doi: 10.1073/pnas.1312951111. Epub 2014 Jan 27.

2.

Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing.

Schoeftner S, Sengupta AK, Kubicek S, Mechtler K, Spahn L, Koseki H, Jenuwein T, Wutz A.

EMBO J. 2006 Jul 12;25(13):3110-22. Epub 2006 Jun 8.

3.

The Xist RNA-PRC2 complex at 20-nm resolution reveals a low Xist stoichiometry and suggests a hit-and-run mechanism in mouse cells.

Sunwoo H, Wu JY, Lee JT.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4216-25. doi: 10.1073/pnas.1503690112. Epub 2015 Jul 20.

4.

Xist localization and function: new insights from multiple levels.

Cerase A, Pintacuda G, Tattermusch A, Avner P.

Genome Biol. 2015 Aug 15;16:166. doi: 10.1186/s13059-015-0733-y. Review.

5.

2-D structure of the A region of Xist RNA and its implication for PRC2 association.

Maenner S, Blaud M, Fouillen L, Savoye A, Marchand V, Dubois A, Sanglier-Cianférani S, Van Dorsselaer A, Clerc P, Avner P, Visvikis A, Branlant C.

PLoS Biol. 2010 Jan;8(1):e1000276. doi: 10.1371/journal.pbio.1000276. Epub 2010 Jan 5.

6.

Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome.

da Rocha ST, Boeva V, Escamilla-Del-Arenal M, Ancelin K, Granier C, Matias NR, Sanulli S, Chow J, Schulz E, Picard C, Kaneko S, Helin K, Reinberg D, Stewart AF, Wutz A, Margueron R, Heard E.

Mol Cell. 2014 Jan 23;53(2):301-16. doi: 10.1016/j.molcel.2014.01.002.

7.

ATRX directs binding of PRC2 to Xist RNA and Polycomb targets.

Sarma K, Cifuentes-Rojas C, Ergun A, Del Rosario A, Jeon Y, White F, Sadreyev R, Lee JT.

Cell. 2014 Nov 6;159(4):869-83. doi: 10.1016/j.cell.2014.10.019. Erratum in: Cell. 2015 Jan 29;160(3):568-9. Cell. 2014 Nov 20;159(5):1228.

8.

Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome.

Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT.

Science. 2008 Oct 31;322(5902):750-6. doi: 10.1126/science.1163045.

9.

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

McHugh CA, Chen CK, Chow A, Surka CF, Tran C, McDonel P, Pandya-Jones A, Blanco M, Burghard C, Moradian A, Sweredoski MJ, Shishkin AA, Su J, Lander ES, Hess S, Plath K, Guttman M.

Nature. 2015 May 14;521(7551):232-6. doi: 10.1038/nature14443. Epub 2015 Apr 27.

10.

Live cell imaging of the nascent inactive X chromosome during the early differentiation process of naive ES cells towards epiblast stem cells.

Guyochin A, Maenner S, Chu ET, Hentati A, Attia M, Avner P, Clerc P.

PLoS One. 2014 Dec 29;9(12):e116109. doi: 10.1371/journal.pone.0116109. eCollection 2014.

11.

Cryptic RNA-binding by PRC2 components EZH2 and SUZ12.

Betancur JG, Tomari Y.

RNA Biol. 2015;12(9):959-65. doi: 10.1080/15476286.2015.1069463.

12.

Noncoding RNA and Polycomb recruitment.

Brockdorff N.

RNA. 2013 Apr;19(4):429-42. doi: 10.1261/rna.037598.112. Epub 2013 Feb 19. Review.

13.

High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation.

Simon MD, Pinter SF, Fang R, Sarma K, Rutenberg-Schoenberg M, Bowman SK, Kesner BA, Maier VK, Kingston RE, Lee JT.

Nature. 2013 Dec 19;504(7480):465-469. doi: 10.1038/nature12719. Epub 2013 Oct 27.

14.

Uncoupling of X-linked gene silencing from XIST binding by DICER1 and chromatin modulation on human inactive X chromosome.

Kota SK, Roy Chowdhury D, Rao LK, Padmalatha V, Singh L, Bhadra U.

Chromosoma. 2015 Jun;124(2):249-62. doi: 10.1007/s00412-014-0495-4. Epub 2014 Nov 27.

PMID:
25428210
15.
16.

Advances in understanding chromosome silencing by the long non-coding RNA Xist.

Sado T, Brockdorff N.

Philos Trans R Soc Lond B Biol Sci. 2013 Jan 5;368(1609):20110325. doi: 10.1098/rstb.2011.0325. Review.

17.

Xist Exon 7 Contributes to the Stable Localization of Xist RNA on the Inactive X-Chromosome.

Yamada N, Hasegawa Y, Yue M, Hamada T, Nakagawa S, Ogawa Y.

PLoS Genet. 2015 Aug 5;11(8):e1005430. doi: 10.1371/journal.pgen.1005430. eCollection 2015 Aug.

18.

Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells.

Monfort A, Di Minin G, Postlmayr A, Freimann R, Arieti F, Thore S, Wutz A.

Cell Rep. 2015 Jul 28;12(4):554-61. doi: 10.1016/j.celrep.2015.06.067. Epub 2015 Jul 16.

19.

Sex-specific silencing of X-linked genes by Xist RNA.

Gayen S, Maclary E, Hinten M, Kalantry S.

Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E309-18. doi: 10.1073/pnas.1515971113. Epub 2016 Jan 6.

20.

Disruption of a conserved region of Xist exon 1 impairs Xist RNA localisation and X-linked gene silencing during random and imprinted X chromosome inactivation.

Senner CE, Nesterova TB, Norton S, Dewchand H, Godwin J, Mak W, Brockdorff N.

Development. 2011 Apr;138(8):1541-50. doi: 10.1242/dev.056812. Epub 2011 Mar 9.

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