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Items: 1 to 20 of 85

1.

Genetic dissection of plexin signaling in vivo.

Worzfeld T, Swiercz JM, Sentürk A, Genz B, Korostylev A, Deng S, Xia J, Hoshino M, Epstein JA, Chan AM, Vollmar B, Acker-Palmer A, Kuner R, Offermanns S.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2194-9. doi: 10.1073/pnas.1308418111. Epub 2014 Jan 27.

2.

Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration.

He H, Yang T, Terman JR, Zhang X.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15610-5. doi: 10.1073/pnas.0906923106. Epub 2009 Aug 26.

3.

Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization.

Wang Y, He H, Srivastava N, Vikarunnessa S, Chen YB, Jiang J, Cowan CW, Zhang X.

Sci Signal. 2012 Jan 17;5(207):ra6. doi: 10.1126/scisignal.2002636. Erratum in: Sci Signal. 2012 Mar 13;5(215):er2.

5.

Semaphorin 4D/Plexin-B1-mediated M-Ras GAP activity regulates actin-based dendrite remodeling through Lamellipodin.

Tasaka G, Negishi M, Oinuma I.

J Neurosci. 2012 Jun 13;32(24):8293-305. doi: 10.1523/JNEUROSCI.0799-12.2012.

6.

Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo.

Deng S, Hirschberg A, Worzfeld T, Penachioni JY, Korostylev A, Swiercz JM, Vodrazka P, Mauti O, Stoeckli ET, Tamagnone L, Offermanns S, Kuner R.

J Neurosci. 2007 Jun 6;27(23):6333-47.

7.

Different requirement for Rnd GTPases of R-Ras GAP activity of Plexin-C1 and Plexin-D1.

Uesugi K, Oinuma I, Katoh H, Negishi M.

J Biol Chem. 2009 Mar 13;284(11):6743-51. doi: 10.1074/jbc.M805213200. Epub 2009 Jan 9.

8.

The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARG.

Aurandt J, Vikis HG, Gutkind JS, Ahn N, Guan KL.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12085-90. Epub 2002 Aug 26.

9.

Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B.

Basile JR, Barac A, Zhu T, Guan KL, Gutkind JS.

Cancer Res. 2004 Aug 1;64(15):5212-24.

10.

Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.

Hota PK, Buck M.

Cell Mol Life Sci. 2012 Nov;69(22):3765-805. doi: 10.1007/s00018-012-1019-0. Epub 2012 Jun 29. Review.

PMID:
22744749
11.

Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF.

Perrot V, Vazquez-Prado J, Gutkind JS.

J Biol Chem. 2002 Nov 8;277(45):43115-20. Epub 2002 Aug 14.

12.

Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain.

Paldy E, Simonetti M, Worzfeld T, Bali KK, Vicuña L, Offermanns S, Kuner R.

Nat Commun. 2017 Aug 2;8(1):176. doi: 10.1038/s41467-017-00341-w.

13.
14.

Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.

Maier V, Jolicoeur C, Rayburn H, Takegahara N, Kumanogoh A, Kikutani H, Tessier-Lavigne M, Wurst W, Friedel RH.

Mol Cell Neurosci. 2011 Feb;46(2):419-31. doi: 10.1016/j.mcn.2010.11.005. Epub 2010 Nov 29.

15.

A systematic expression analysis implicates Plexin-B2 and its ligand Sema4C in the regulation of the vascular and endocrine system.

Zielonka M, Xia J, Friedel RH, Offermanns S, Worzfeld T.

Exp Cell Res. 2010 Sep 10;316(15):2477-86. doi: 10.1016/j.yexcr.2010.05.007. Epub 2010 May 15.

PMID:
20478304
16.

Plexins: axon guidance and signal transduction.

Negishi M, Oinuma I, Katoh H.

Cell Mol Life Sci. 2005 Jun;62(12):1363-71. Review.

PMID:
15818466
17.

Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.

Swiercz JM, Kuner R, Behrens J, Offermanns S.

Neuron. 2002 Jul 3;35(1):51-63.

18.

Semaphorin 4D signaling requires the recruitment of phospholipase C gamma into the plexin-B1 receptor complex.

Swiercz JM, Worzfeld T, Offermanns S.

Mol Cell Biol. 2009 Dec;29(23):6321-34. doi: 10.1128/MCB.00103-09. Epub 2009 Oct 5.

19.

Plexin B3 promotes neurite outgrowth, interacts homophilically, and interacts with Rin.

Hartwig C, Veske A, Krejcova S, Rosenberger G, Finckh U.

BMC Neurosci. 2005 Aug 25;6:53.

20.

Structure and function of the intracellular region of the plexin-b1 transmembrane receptor.

Tong Y, Hota PK, Penachioni JY, Hamaneh MB, Kim S, Alviani RS, Shen L, He H, Tempel W, Tamagnone L, Park HW, Buck M.

J Biol Chem. 2009 Dec 18;284(51):35962-72. doi: 10.1074/jbc.M109.056275.

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