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Items: 1 to 20 of 91


Binding of HSV-1 glycoprotein K (gK) to signal peptide peptidase (SPP) is required for virus infectivity.

Allen SJ, Mott KR, Matsuura Y, Moriishi K, Kousoulas KG, Ghiasi H.

PLoS One. 2014 Jan 20;9(1):e85360. doi: 10.1371/journal.pone.0085360. eCollection 2014.


Binding of Herpes Simplex Virus 1 UL20 to GODZ (DHHC3) Affects Its Palmitoylation and Is Essential for Infectivity and Proper Targeting and Localization of UL20 and Glycoprotein K.

Wang S, Mott KR, Wawrowsky K, Kousoulas KG, Luscher B, Ghiasi H.

J Virol. 2017 Sep 12;91(19). pii: e00945-17. doi: 10.1128/JVI.00945-17. Print 2017 Oct 1.


A herpes simplex virus 1 (McKrae) mutant lacking the glycoprotein K gene is unable to infect via neuronal axons and egress from neuronal cell bodies.

David AT, Saied A, Charles A, Subramanian R, Chouljenko VN, Kousoulas KG.

MBio. 2012 Jul 24;3(4):e00144-12. doi: 10.1128/mBio.00144-12. Print 2012.


Cysteines and N-Glycosylation Sites Conserved among All Alphaherpesviruses Regulate Membrane Fusion in Herpes Simplex Virus 1 Infection.

Rider PJF, Naderi M, Bergeron S, Chouljenko VN, Brylinski M, Kousoulas KG.

J Virol. 2017 Oct 13;91(21). pii: e00873-17. doi: 10.1128/JVI.00873-17. Print 2017 Nov 1.


Herpes simplex virus glycoprotein K promotes egress of virus particles.

Hutchinson L, Johnson DC.

J Virol. 1995 Sep;69(9):5401-13.


The Amino Terminus of Herpes Simplex Virus 1 Glycoprotein K (gK) Is Required for gB Binding to Akt, Release of Intracellular Calcium, and Fusion of the Viral Envelope with Plasma Membranes.

Musarrat F, Jambunathan N, Rider PJF, Chouljenko VN, Kousoulas KG.

J Virol. 2018 Feb 26;92(6). pii: e01842-17. doi: 10.1128/JVI.01842-17. Print 2018 Mar 15.


Herpes simplex virus 1 protein UL37 interacts with viral glycoprotein gK and membrane protein UL20 and functions in cytoplasmic virion envelopment.

Jambunathan N, Chouljenko D, Desai P, Charles AS, Subramanian R, Chouljenko VN, Kousoulas KG.

J Virol. 2014 Jun;88(11):5927-35. doi: 10.1128/JVI.00278-14. Epub 2014 Mar 5.


Site-specific proteolytic cleavage of the amino terminus of herpes simplex virus glycoprotein K on virion particles inhibits virus entry.

Jambunathan N, Chowdhury S, Subramanian R, Chouljenko VN, Walker JD, Kousoulas KG.

J Virol. 2011 Dec;85(24):12910-8. doi: 10.1128/JVI.06268-11. Epub 2011 Oct 12.


Inhibitors of signal peptide peptidase (SPP) affect HSV-1 infectivity in vitro and in vivo.

Allen SJ, Mott KR, Ghiasi H.

Exp Eye Res. 2014 Jun;123:8-15. doi: 10.1016/j.exer.2014.04.004. Epub 2014 Apr 24.


A replication competent HSV-1(McKrae) with a mutation in the amino-terminus of glycoprotein K (gK) is unable to infect mouse trigeminal ganglia after cornea infection.

Saied AA, Chouljenko VN, Subramanian R, Kousoulas KG.

Curr Eye Res. 2014 Jun;39(6):596-603. doi: 10.3109/02713683.2013.855238. Epub 2014 Jan 8.


The amino terminus of herpes simplex virus type 1 glycoprotein K (gK) modulates gB-mediated virus-induced cell fusion and virion egress.

Chouljenko VN, Iyer AV, Chowdhury S, Chouljenko DV, Kousoulas KG.

J Virol. 2009 Dec;83(23):12301-13. doi: 10.1128/JVI.01329-09. Epub 2009 Sep 30.


Phenylalanine residues at the carboxyl terminus of the herpes simplex virus 1 UL20 membrane protein regulate cytoplasmic virion envelopment and infectious virus production.

Charles AS, Chouljenko VN, Jambunathan N, Subramanian R, Mottram P, Kousoulas KG.

J Virol. 2014 Jul;88(13):7618-27. doi: 10.1128/JVI.00657-14. Epub 2014 Apr 23.


Herpes Simplex Virus 1 UL37 Protein Tyrosine Residues Conserved among All Alphaherpesviruses Are Required for Interactions with Glycoprotein K, Cytoplasmic Virion Envelopment, and Infectious Virus Production.

Chouljenko DV, Jambunathan N, Chouljenko VN, Naderi M, Brylinski M, Caskey JR, Kousoulas KG.

J Virol. 2016 Oct 28;90(22):10351-10361. Print 2016 Nov 15.


The herpes simplex virus type 1 UL20 protein and the amino terminus of glycoprotein K (gK) physically interact with gB.

Chouljenko VN, Iyer AV, Chowdhury S, Kim J, Kousoulas KG.

J Virol. 2010 Sep;84(17):8596-606. doi: 10.1128/JVI.00298-10. Epub 2010 Jun 23.

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