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Items: 1 to 20 of 126

1.

Tissue kallikrein protects rat hippocampal CA1 neurons against cerebral ischemia/reperfusion-induced injury through the B2R-Raf-MEK1/2-ERK1/2 pathway.

Wang Z, Han X, Cui M, Fang K, Lu Z, Dong Q.

J Neurosci Res. 2014 May;92(5):651-7. doi: 10.1002/jnr.23325. Epub 2014 Jan 27.

PMID:
24464837
2.

The neuroprotective effect of losartan through inhibiting AT1/ASK1/MKK4/JNK3 pathway following cerebral I/R in rat hippocampal CA1 region.

Zhang TL, Fu JL, Geng Z, Yang JJ, Sun XJ.

CNS Neurosci Ther. 2012 Dec;18(12):981-7. doi: 10.1111/cns.12015. Epub 2012 Oct 25.

PMID:
23095236
3.

Tissue kallikrein protects neurons from hypoxia/reoxygenation-induced cell injury through Homer1b/c.

Su J, Tang Y, Zhou H, Liu L, Dong Q.

Cell Signal. 2012 Nov;24(11):2205-15. doi: 10.1016/j.cellsig.2012.04.021. Epub 2012 May 7.

PMID:
22575735
4.

Rosmarinic acid protects rat hippocampal neurons from cerebral ischemia/reperfusion injury via the Akt/JNK3/caspase-3 signaling pathway.

Zhang M, Yan H, Li S, Yang J.

Brain Res. 2017 Feb 15;1657:9-15. doi: 10.1016/j.brainres.2016.11.032. Epub 2016 Dec 5.

PMID:
27923634
5.

Fasudil hydrochloride protects neurons in rat hippocampal CA1 region through inhibiting GluR6-MLK3-JNKs signal pathway.

Wei XE, Zhang FY, Wang K, Zhang QX, Rong LQ.

Cell Biochem Biophys. 2014 Sep;70(1):415-21. doi: 10.1007/s12013-014-9931-6.

PMID:
24793642
6.

Tissue kallikrein protects SH-SY5Y neuronal cells against oxygen and glucose deprivation-induced injury through bradykinin B2 receptor-dependent regulation of autophagy induction.

Liu Y, Lu Z, Cui M, Yang Q, Tang Y, Dong Q.

J Neurochem. 2016 Oct;139(2):208-220. doi: 10.1111/jnc.13690. Epub 2016 Sep 15.

PMID:
27248356
7.

Tissue kallikrein protects cortical neurons against in vitro ischemia-acidosis/reperfusion-induced injury through the ERK1/2 pathway.

Liu L, Zhang R, Liu K, Zhou H, Yang X, Liu X, Tang M, Su J, Dong Q.

Exp Neurol. 2009 Oct;219(2):453-65. doi: 10.1016/j.expneurol.2009.06.021. Epub 2009 Jul 2.

PMID:
19576887
8.

Tissue kallikrein alleviates glutamate-induced neurotoxicity by activating ERK1.

Liu L, Zhang R, Liu K, Zhou H, Tang Y, Su J, Yu X, Yang X, Tang M, Dong Q.

J Neurosci Res. 2009 Dec;87(16):3576-90. doi: 10.1002/jnr.22151.

PMID:
19598250
9.

Transforming growth-beta 1 contributes to isoflurane postconditioning against cerebral ischemia-reperfusion injury by regulating the c-Jun N-terminal kinase signaling pathway.

Wang S, Yin J, Ge M, Dai Z, Li Y, Si J, Ma K, Li L, Yao S.

Biomed Pharmacother. 2016 Mar;78:280-90. doi: 10.1016/j.biopha.2016.01.030. Epub 2016 Feb 4.

PMID:
26898453
10.

Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats.

Zhu YM, Wang CC, Chen L, Qian LB, Ma LL, Yu J, Zhu MH, Wen CY, Yu LN, Yan M.

Brain Res. 2013 Feb 4;1494:1-8. doi: 10.1016/j.brainres.2012.11.047. Epub 2012 Dec 5.

PMID:
23219579
11.

Tissue kallikrein protects cortical neurons against hypoxia/reoxygenation injury via the ERK1/2 pathway.

Liu L, Liu H, Yang F, Chen G, Zhou H, Tang M, Zhang R, Dong Q.

Biochem Biophys Res Commun. 2011 Apr 8;407(2):283-7. doi: 10.1016/j.bbrc.2011.02.112. Epub 2011 Mar 3.

PMID:
21376701
12.

Metformin protects the brain against ischemia/reperfusion injury through PI3K/Akt1/JNK3 signaling pathways in rats.

Ge XH, Zhu GJ, Geng DQ, Zhang HZ, He JM, Guo AZ, Ma LL, Yu DH.

Physiol Behav. 2017 Mar 1;170:115-123. doi: 10.1016/j.physbeh.2016.12.021. Epub 2016 Dec 23.

PMID:
28017679
13.

K252a suppresses neuronal cells apoptosis through inhibiting the translocation of Bax to mitochondria induced by the MLK3/JNK signaling after transient global brain ischemia in rat hippocampal CA1 subregion.

Wang Q, Yin XH, Liu Y, Zhang GY.

J Recept Signal Transduct Res. 2011 Aug;31(4):307-13. doi: 10.3109/10799893.2011.592536. Epub 2011 Jul 5.

PMID:
21726169
14.

Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis.

Guan QH, Pei DS, Liu XM, Wang XT, Xu TL, Zhang GY.

Brain Res. 2006 May 30;1092(1):36-46. Epub 2006 May 3.

PMID:
16674927
15.

Attenuation of mitochondrial and nuclear p38α signaling: a novel mechanism of estrogen neuroprotection in cerebral ischemia.

Han D, Scott EL, Dong Y, Raz L, Wang R, Zhang Q.

Mol Cell Endocrinol. 2015 Jan 15;400:21-31. doi: 10.1016/j.mce.2014.11.010. Epub 2014 Nov 25.

PMID:
25462588
16.

Cerebralcare Granule, a Chinese herb compound preparation, improves cerebral microcirculatory disorder and hippocampal CA1 neuron injury in gerbils after ischemia-reperfusion.

Sun K, Hu Q, Zhou CM, Xu XS, Wang F, Hu BH, Zhao XY, Chang X, Chen CH, Huang P, An LH, Liu YY, Fan JY, Wang CS, Yang L, Han JY.

J Ethnopharmacol. 2010 Jul 20;130(2):398-406. doi: 10.1016/j.jep.2010.05.030. Epub 2010 May 24.

PMID:
20580803
17.

Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3.

Hu Y, Duan M, Liang S, Wang Y, Feng Y.

Brain Res. 2015 Apr 24;1605:39-48. doi: 10.1016/j.brainres.2015.02.015. Epub 2015 Feb 16.

PMID:
25698615
18.

Neuroprotection of Sevoflurane Against Ischemia/Reperfusion-Induced Brain Injury Through Inhibiting JNK3/Caspase-3 by Enhancing Akt Signaling Pathway.

Wen XR, Fu YY, Liu HZ, Wu J, Shao XP, Zhang XB, Tang M, Shi Y, Ma K, Zhang F, Wang YW, Tang H, Han D, Zhang P, Wang SL, Xu Z, Song YJ.

Mol Neurobiol. 2016 Apr;53(3):1661-1671. doi: 10.1007/s12035-015-9111-8. Epub 2015 Feb 17.

PMID:
25687432
19.

Antioxidant effect of salvianolic acid B on hippocampal CA1 neurons in mice with cerebral ischemia and reperfusion injury.

Jiang YF, Liu ZQ, Cui W, Zhang WT, Gong JP, Wang XM, Zhang Y, Yang MJ.

Chin J Integr Med. 2015 Jul;21(7):516-22. doi: 10.1007/s11655-014-1791-1. Epub 2014 Jul 31.

PMID:
25081897
20.

Tissue Kallikrein Alleviates Cerebral Ischemia-Reperfusion Injury by Activating the B2R-ERK1/2-CREB-Bcl-2 Signaling Pathway in Diabetic Rats.

Shi R, Yuan K, Hu B, Sang H, Zhou L, Xie Y, Xu L, Cao Q, Chen X, Zhao L, Xiong Y, Xu G, Liu X, Liu L, Zhang R.

Oxid Med Cell Longev. 2016;2016:1843201. Epub 2016 Jun 30.

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