Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 109

1.

Nonclassical transpeptidases of Mycobacterium tuberculosis alter cell size, morphology, the cytosolic matrix, protein localization, virulence, and resistance to β-lactams.

Schoonmaker MK, Bishai WR, Lamichhane G.

J Bacteriol. 2014 Apr;196(7):1394-402. doi: 10.1128/JB.01396-13. Epub 2014 Jan 24.

2.

Non-classical transpeptidases yield insight into new antibacterials.

Kumar P, Kaushik A, Lloyd EP, Li SG, Mattoo R, Ammerman NC, Bell DT, Perryman AL, Zandi TA, Ekins S, Ginell SL, Townsend CA, Freundlich JS, Lamichhane G.

Nat Chem Biol. 2017 Jan;13(1):54-61. doi: 10.1038/nchembio.2237. Epub 2016 Nov 7.

3.

Structures of free and inhibited forms of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis.

Correale S, Ruggiero A, Capparelli R, Pedone E, Berisio R.

Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1697-706. doi: 10.1107/S0907444913013085. Epub 2013 Aug 15.

PMID:
23999293
4.

The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin.

Gupta R, Lavollay M, Mainardi JL, Arthur M, Bishai WR, Lamichhane G.

Nat Med. 2010 Apr;16(4):466-9. doi: 10.1038/nm.2120. Epub 2010 Mar 21.

5.

In vitro cross-linking of Mycobacterium tuberculosis peptidoglycan by L,D-transpeptidases and inactivation of these enzymes by carbapenems.

Cordillot M, Dubée V, Triboulet S, Dubost L, Marie A, Hugonnet JE, Arthur M, Mainardi JL.

Antimicrob Agents Chemother. 2013 Dec;57(12):5940-5. doi: 10.1128/AAC.01663-13. Epub 2013 Sep 16.

6.

Binding and processing of β-lactam antibiotics by the transpeptidase LdtMt2 from Mycobacterium tuberculosis.

Steiner EM, Schneider G, Schnell R.

FEBS J. 2017 Mar;284(5):725-741. doi: 10.1111/febs.14010. Epub 2017 Feb 8.

PMID:
28075068
7.

The beta-lactam-sensitive D,D-carboxypeptidase activity of Pbp4 controls the L,D and D,D transpeptidation pathways in Corynebacterium jeikeium.

Lavollay M, Arthur M, Fourgeaud M, Dubost L, Marie A, Riegel P, Gutmann L, Mainardi JL.

Mol Microbiol. 2009 Nov;74(3):650-61. doi: 10.1111/j.1365-2958.2009.06887.x. Epub 2009 Oct 6.

8.

Structural basis for the inhibition of Mycobacterium tuberculosis L,D-transpeptidase by meropenem, a drug effective against extensively drug-resistant strains.

Kim HS, Kim J, Im HN, Yoon JY, An DR, Yoon HJ, Kim JY, Min HK, Kim SJ, Lee JY, Han BW, Suh SW.

Acta Crystallogr D Biol Crystallogr. 2013 Mar;69(Pt 3):420-31. doi: 10.1107/S0907444912048998. Epub 2013 Feb 16.

9.

Genetic characterization of mycobacterial L,D-transpeptidases.

Sanders AN, Wright LF, Pavelka MS Jr.

Microbiology. 2014 Aug;160(Pt 8):1795-806. doi: 10.1099/mic.0.078980-0. Epub 2014 May 21.

10.

Acyl acceptor recognition by Enterococcus faecium L,D-transpeptidase Ldtfm.

Triboulet S, Bougault CM, Laguri C, Hugonnet JE, Arthur M, Simorre JP.

Mol Microbiol. 2015 Oct;98(1):90-100. doi: 10.1111/mmi.13104. Epub 2015 Jul 17.

11.

Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance.

Filippova EV, Kieser KJ, Luan CH, Wawrzak Z, Kiryukhina O, Rubin EJ, Anderson WF.

FEBS J. 2016 Jun;283(12):2206-18. doi: 10.1111/febs.13738. Epub 2016 May 25.

12.

The peptidoglycan of stationary-phase Mycobacterium tuberculosis predominantly contains cross-links generated by L,D-transpeptidation.

Lavollay M, Arthur M, Fourgeaud M, Dubost L, Marie A, Veziris N, Blanot D, Gutmann L, Mainardi JL.

J Bacteriol. 2008 Jun;190(12):4360-6. doi: 10.1128/JB.00239-08. Epub 2008 Apr 11.

13.

Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis.

Brammer Basta LA, Ghosh A, Pan Y, Jakoncic J, Lloyd EP, Townsend CA, Lamichhane G, Bianchet MA.

J Biol Chem. 2015 Oct 16;290(42):25670-85. doi: 10.1074/jbc.M115.660753. Epub 2015 Aug 24.

14.

Inactivation of Rv2525c, a substrate of the twin arginine translocation (Tat) system of Mycobacterium tuberculosis, increases beta-lactam susceptibility and virulence.

Saint-Joanis B, Demangel C, Jackson M, Brodin P, Marsollier L, Boshoff H, Cole ST.

J Bacteriol. 2006 Sep;188(18):6669-79.

15.

Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of L,D-Transpeptidase LdtMt1 of Mycobacterium tuberculosis and the Stability toward Hydrolysis by β-Lactamase BlaC.

Iannazzo L, Soroka D, Triboulet S, Fonvielle M, Compain F, Dubée V, Mainardi JL, Hugonnet JE, Braud E, Arthur M, Etheve-Quelquejeu M.

J Med Chem. 2016 Apr 14;59(7):3427-38. doi: 10.1021/acs.jmedchem.6b00096. Epub 2016 Mar 18.

PMID:
26937999
16.

Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem.

Bianchet MA, Pan YH, Basta LAB, Saavedra H, Lloyd EP, Kumar P, Mattoo R, Townsend CA, Lamichhane G.

BMC Biochem. 2017 May 25;18(1):8. doi: 10.1186/s12858-017-0082-4.

17.

Structure of Enterococcus faeciuml,d-transpeptidase acylated by ertapenem provides insight into the inactivation mechanism.

Lecoq L, Dubée V, Triboulet S, Bougault C, Hugonnet JE, Arthur M, Simorre JP.

ACS Chem Biol. 2013;8(6):1140-6. doi: 10.1021/cb4001603. Epub 2013 Apr 12.

18.

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis.

Correale S, Ruggiero A, Pedone E, Berisio R.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):253-6. doi: 10.1107/S1744309112052141. Epub 2013 Feb 22.

19.

Unexpected inhibition of peptidoglycan LD-transpeptidase from Enterococcus faecium by the beta-lactam imipenem.

Mainardi JL, Hugonnet JE, Rusconi F, Fourgeaud M, Dubost L, Moumi AN, Delfosse V, Mayer C, Gutmann L, Rice LB, Arthur M.

J Biol Chem. 2007 Oct 19;282(42):30414-22. Epub 2007 Jul 23.

20.

Chemical shift perturbations induced by the acylation of Enterococcus faecium L,D-transpeptidase catalytic cysteine with ertapenem.

Lecoq L, Bougault C, Triboulet S, Dubée V, Hugonnet JE, Arthur M, Simorre JP.

Biomol NMR Assign. 2014 Oct;8(2):339-43. doi: 10.1007/s12104-013-9513-3. Epub 2013 Aug 2.

PMID:
23907322

Supplemental Content

Support Center