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Items: 1 to 20 of 87

1.

Efficient and rapid induction of human iPSCs/ESCs into nephrogenic intermediate mesoderm using small molecule-based differentiation methods.

Araoka T, Mae S, Kurose Y, Uesugi M, Ohta A, Yamanaka S, Osafune K.

PLoS One. 2014 Jan 15;9(1):e84881. doi: 10.1371/journal.pone.0084881. eCollection 2014.

2.

Rapid and efficient differentiation of human pluripotent stem cells into intermediate mesoderm that forms tubules expressing kidney proximal tubular markers.

Lam AQ, Freedman BS, Morizane R, Lerou PH, Valerius MT, Bonventre JV.

J Am Soc Nephrol. 2014 Jun;25(6):1211-25. doi: 10.1681/ASN.2013080831. Epub 2013 Dec 19.

3.

Combination of small molecules enhances differentiation of mouse embryonic stem cells into intermediate mesoderm through BMP7-positive cells.

Mae S, Shirasawa S, Yoshie S, Sato F, Kanoh Y, Ichikawa H, Yokoyama T, Yue F, Tomotsune D, Sasaki K.

Biochem Biophys Res Commun. 2010 Mar 19;393(4):877-82. doi: 10.1016/j.bbrc.2010.02.111. Epub 2010 Feb 19.

PMID:
20171952
4.

Induction of intermediate mesoderm by retinoic acid receptor signaling from differentiating mouse embryonic stem cells.

Oeda S, Hayashi Y, Chan T, Takasato M, Aihara Y, Okabayashi K, Ohnuma K, Asashima M.

Int J Dev Biol. 2013;57(5):383-9. doi: 10.1387/ijdb.130058ma.

5.

Small-molecule inhibitors of the Wnt pathway potently promote cardiomyocytes from human embryonic stem cell-derived mesoderm.

Willems E, Spiering S, Davidovics H, Lanier M, Xia Z, Dawson M, Cashman J, Mercola M.

Circ Res. 2011 Aug 5;109(4):360-4. doi: 10.1161/CIRCRESAHA.111.249540. Epub 2011 Jul 7.

6.

Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells.

Mae S, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda-Nishimura N, Arai S, Sato-Otubo A, Toyoda T, Takahashi K, Nakayama N, Cowan CA, Aoi T, Ogawa S, McMahon AP, Yamanaka S, Osafune K.

Nat Commun. 2013;4:1367. doi: 10.1038/ncomms2378.

7.

Small molecule-directed specification of sclerotome-like chondroprogenitors and induction of a somitic chondrogenesis program from embryonic stem cells.

Zhao J, Li S, Trilok S, Tanaka M, Jokubaitis-Jameson V, Wang B, Niwa H, Nakayama N.

Development. 2014 Oct;141(20):3848-58. doi: 10.1242/dev.105981.

8.

Stepwise renal lineage differentiation of mouse embryonic stem cells tracing in vivo development.

Nishikawa M, Yanagawa N, Kojima N, Yuri S, Hauser PV, Jo OD, Yanagawa N.

Biochem Biophys Res Commun. 2012 Jan 13;417(2):897-902. doi: 10.1016/j.bbrc.2011.12.071. Epub 2011 Dec 22.

PMID:
22209845
9.

Directed cardiomyogenesis of human pluripotent stem cells by modulating Wnt/β-catenin and BMP signalling with small molecules.

Aguilar JS, Begum AN, Alvarez J, Zhang XB, Hong Y, Hao J.

Biochem J. 2015 Jul 15;469(2):235-41. doi: 10.1042/BJ20150186.

PMID:
26171831
10.

Regulation of pluripotent cell differentiation by a small molecule, staurosporine.

Hughes JN, Wong CK, Lau KX, Rathjen PD, Rathjen J.

Differentiation. 2014 Mar-Apr;87(3-4):101-10. doi: 10.1016/j.diff.2014.01.001. Epub 2014 Feb 28.

PMID:
24582574
11.

Chemical inhibition of sulfation accelerates neural differentiation of mouse embryonic stem cells and human induced pluripotent stem cells.

Sasaki N, Hirano T, Kobayashi K, Toyoda M, Miyakawa Y, Okita H, Kiyokawa N, Akutsu H, Umezawa A, Nishihara S.

Biochem Biophys Res Commun. 2010 Oct 22;401(3):480-6. doi: 10.1016/j.bbrc.2010.09.085. Epub 2010 Sep 25.

PMID:
20875394
12.

Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells.

Kraushaar DC, Rai S, Condac E, Nairn A, Zhang S, Yamaguchi Y, Moremen K, Dalton S, Wang L.

J Biol Chem. 2012 Jun 29;287(27):22691-700. doi: 10.1074/jbc.M112.368241. Epub 2012 May 3.

13.

In vitro differentiation of murine embryonic stem cells toward a renal lineage.

Bruce SJ, Rea RW, Steptoe AL, Busslinger M, Bertram JF, Perkins AC.

Differentiation. 2007 Jun;75(5):337-49. Epub 2007 Feb 5.

PMID:
17286599
14.

Small molecule mesengenic induction of human induced pluripotent stem cells to generate mesenchymal stem/stromal cells.

Chen YS, Pelekanos RA, Ellis RL, Horne R, Wolvetang EJ, Fisk NM.

Stem Cells Transl Med. 2012 Feb;1(2):83-95. doi: 10.5966/sctm.2011-0022. Epub 2012 Feb 7.

15.

Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells.

Umeda K, Zhao J, Simmons P, Stanley E, Elefanty A, Nakayama N.

Sci Rep. 2012;2:455. doi: 10.1038/srep00455. Epub 2012 Jun 13.

16.

Wnt and Notch signals guide embryonic stem cell differentiation into the intestinal lineages.

Ogaki S, Shiraki N, Kume K, Kume S.

Stem Cells. 2013 Jun;31(6):1086-96. doi: 10.1002/stem.1344.

18.

Differentiation of murine embryonic stem cells toward renal lineages by conditioned medium from ureteric bud cells in vitro.

Ren X, Zhang J, Gong X, Niu X, Zhang X, Chen P, Zhang X.

Acta Biochim Biophys Sin (Shanghai). 2010 Jul;42(7):464-71. doi: 10.1093/abbs/gmq046. Epub 2010 Jun 8.

19.

Signaling pathways controlling pluripotency and early cell fate decisions of human induced pluripotent stem cells.

Vallier L, Touboul T, Brown S, Cho C, Bilican B, Alexander M, Cedervall J, Chandran S, Ahrlund-Richter L, Weber A, Pedersen RA.

Stem Cells. 2009 Nov;27(11):2655-66. doi: 10.1002/stem.199.

20.

Directing differentiation of human embryonic stem cells toward anterior neural ectoderm using small molecules.

Surmacz B, Fox H, Gutteridge A, Fish P, Lubitz S, Whiting P.

Stem Cells. 2012 Sep;30(9):1875-84. doi: 10.1002/stem.1166. Erratum in: Stem Cells. 2013 Jul;31(7):1446. Fish, Paul [added].

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