Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 99


Blockade of 4-1BB and 4-1BBL interaction reduces obesity-induced skeletal muscle inflammation.

Le NH, Kim CS, Tu TH, Choi HS, Kim BS, Kawada T, Goto T, Park T, Park JH, Yu R.

Mediators Inflamm. 2013;2013:865159. doi: 10.1155/2013/865159. Epub 2013 Dec 18.


4-1BB/4-1BBL interaction promotes obesity-induced adipose inflammation by triggering bidirectional inflammatory signaling in adipocytes/macrophages.

Tu TH, Kim CS, Goto T, Kawada T, Kim BS, Yu R.

Mediators Inflamm. 2012;2012:972629. doi: 10.1155/2012/972629. Epub 2012 Dec 17.


Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders.

Kim CS, Kim JG, Lee BJ, Choi MS, Choi HS, Kawada T, Lee KU, Yu R.

Diabetes. 2011 Dec;60(12):3159-68. doi: 10.2337/db10-1805. Epub 2011 Oct 13.


The 4-1BB ligand and 4-1BB expressed on osteoclast precursors enhance RANKL-induced osteoclastogenesis via bi-directional signaling.

Yang J, Park OJ, Lee YJ, Jung HM, Woo KM, Choi Y.

Eur J Immunol. 2008 Jun;38(6):1598-609. doi: 10.1002/eji.200737650.


Dispensable role for 4-1BB and 4-1BBL in development of vaccinia virus-specific CD8 T cells.

Zhao Y, Croft M.

Immunol Lett. 2012 Jan 30;141(2):220-6. doi: 10.1016/j.imlet.2011.10.008. Epub 2011 Oct 20.


Distinct approaches to investigate the importance of the murine 4-1BB 4-1BBL interaction in the antibody response to Streptococcus pneumoniae.

Moens L, Jeurissen A, Mittler RS, Wuyts G, Michiels G, Boon L, Ceuppens JL, Bossuyt X.

J Leukoc Biol. 2007 Sep;82(3):638-44. Epub 2007 Jun 5.


Endogenous 4-1BB ligand plays a critical role in protection from influenza-induced disease.

Lin GH, Sedgmen BJ, Moraes TJ, Snell LM, Topham DJ, Watts TH.

J Immunol. 2009 Jan 15;182(2):934-47.


Constitutive interaction between 4-1BB and 4-1BBL on murine LPS-activated bone marrow dendritic cells masks detection of 4-1BBL by TKS-1 but not 19H3 antibody.

Mbanwi AN, Lin GHY, Wang KC, Watts TH.

J Immunol Methods. 2017 Nov;450:81-89. doi: 10.1016/j.jim.2017.08.001. Epub 2017 Aug 5.


CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice.

Jeon HJ, Choi JH, Jung IH, Park JG, Lee MR, Lee MN, Kim B, Yoo JY, Jeong SJ, Kim DY, Park JE, Park HY, Kwack K, Choi BK, Kwon BS, Oh GT.

Circulation. 2010 Mar 9;121(9):1124-33. doi: 10.1161/CIRCULATIONAHA.109.882704. Epub 2010 Feb 22.


Expression of 4-1BB and 4-1BBL in thymocytes during thymus regeneration.

Kim YM, Kim HK, Kim HJ, Lee HW, Ju SA, Choi BK, Kwon BS, Kim BS, Kim JB, Lim YT, Yoon S.

Exp Mol Med. 2009 Dec 31;41(12):896-911. doi: 10.3858/emm.2009.41.12.095.


Blockade of the 4-1BB (CD137)/4-1BBL and/or CD28/CD80/CD86 costimulatory pathways promotes corneal allograft survival in mice.

Asai T, Choi BK, Kwon PM, Kim WY, Kim JD, Vinay DS, Gebhardt BM, Kwon BS.

Immunology. 2007 Jul;121(3):349-58. Epub 2007 Mar 22.


4-1BBL signaling promotes cell proliferation through reprogramming of glucose metabolism in monocytes/macrophages.

Tu TH, Kim CS, Nam-Goong IS, Nam CW, Kim YI, Goto T, Kawada T, Park T, Yoon Park JH, Ryoo ZY, Park JW, Choi HS, Yu R.

FEBS J. 2015 Apr;282(8):1468-80. doi: 10.1111/febs.13236. Epub 2015 Mar 13.


Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells.

Futagawa T, Akiba H, Kodama T, Takeda K, Hosoda Y, Yagita H, Okumura K.

Int Immunol. 2002 Mar;14(3):275-86.


4-1BB ligand signaling to T cells limits T cell activation.

Eun SY, Lee SW, Xu Y, Croft M.

J Immunol. 2015 Jan 1;194(1):134-41. doi: 10.4049/jimmunol.1401383. Epub 2014 Nov 17.


The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily.

Won EY, Cha K, Byun JS, Kim DU, Shin S, Ahn B, Kim YH, Rice AJ, Walz T, Kwon BS, Cho HS.

J Biol Chem. 2010 Mar 19;285(12):9202-10. doi: 10.1074/jbc.M109.084442. Epub 2009 Dec 23.


Inhibition of 4-1BBL-regulated TLR response in macrophages ameliorates endotoxin-induced sepsis in mice.

Bang BR, Kim SJ, Yagita H, Croft M, Kang YJ.

Eur J Immunol. 2015 Mar;45(3):886-92. doi: 10.1002/eji.201445174. Epub 2015 Jan 21.


Quercetin protects against obesity-induced skeletal muscle inflammation and atrophy.

Le NH, Kim CS, Park T, Park JH, Sung MK, Lee DG, Hong SM, Choe SY, Goto T, Kawada T, Yu R.

Mediators Inflamm. 2014;2014:834294. doi: 10.1155/2014/834294. Epub 2014 Dec 28.


Blockade of the 4-1BB pathway attenuates graft arterial disease in cardiac allografts.

Saiki H, Suzuki J, Kosuge H, Haraguchi G, Ishihara T, Haga T, Maejima Y, Isobe M, Uede T.

Int Heart J. 2008 Jan;49(1):105-18.


Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters.

Tu TH, Kim CS, Kang JH, Nam-Goong IS, Nam CW, Kim ES, Kim YI, Choi JI, Kawada T, Goto T, Park T, Yoon Park JH, Choi MS, Yu R.

Int J Obes (Lond). 2014 Aug;38(8):1075-82. doi: 10.1038/ijo.2013.222. Epub 2013 Nov 27.


The immune signaling molecule 4-1BB stimulation reduces adiposity, insulin resistance, and hepatosteatosis in obese mice.

Kim CS, Tu TH, Kawada T, Kim BS, Yu R.

Endocrinology. 2010 Oct;151(10):4725-35. doi: 10.1210/en.2010-0346. Epub 2010 Aug 18.


Supplemental Content

Support Center