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Items: 1 to 20 of 98

1.

Probing large conformational rearrangements in wild-type and mutant spectrin using structural mass spectrometry.

Sriswasdi S, Harper SL, Tang HY, Gallagher PG, Speicher DW.

Proc Natl Acad Sci U S A. 2014 Feb 4;111(5):1801-6. doi: 10.1073/pnas.1317620111. Epub 2014 Jan 22.

2.

The common hereditary elliptocytosis-associated α-spectrin L260P mutation perturbs erythrocyte membranes by stabilizing spectrin in the closed dimer conformation.

Harper SL, Sriswasdi S, Tang HY, Gaetani M, Gallagher PG, Speicher DW.

Blood. 2013 Oct 24;122(17):3045-53. doi: 10.1182/blood-2013-02-487702. Epub 2013 Aug 23.

3.

A fused alpha-beta "mini-spectrin" mimics the intact erythrocyte spectrin head-to-head tetramer.

Harper SL, Li D, Maksimova Y, Gallagher PG, Speicher DW.

J Biol Chem. 2010 Apr 2;285(14):11003-12. doi: 10.1074/jbc.M109.083048. Epub 2010 Feb 5.

4.

A comprehensive model of the spectrin divalent tetramer binding region deduced using homology modeling and chemical cross-linking of a mini-spectrin.

Li D, Harper SL, Tang HY, Maksimova Y, Gallagher PG, Speicher DW.

J Biol Chem. 2010 Sep 17;285(38):29535-45. doi: 10.1074/jbc.M110.145573. Epub 2010 Jul 6.

5.

Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex.

Ipsaro JJ, Harper SL, Messick TE, Marmorstein R, Mondragón A, Speicher DW.

Blood. 2010 Jun 10;115(23):4843-52. doi: 10.1182/blood-2010-01-261396. Epub 2010 Mar 2.

6.

Interactions of spectrin in hereditary elliptocytes containing truncated spectrin beta-chains.

Eber SW, Morris SA, Schröter W, Gratzer WB.

J Clin Invest. 1988 Feb;81(2):523-30.

7.
8.

Structural and functional effects of hereditary hemolytic anemia-associated point mutations in the alpha spectrin tetramer site.

Gaetani M, Mootien S, Harper S, Gallagher PG, Speicher DW.

Blood. 2008 Jun 15;111(12):5712-20. doi: 10.1182/blood-2007-11-122457. Epub 2008 Jan 24.

9.

Location of the human red cell spectrin tetramer binding site and detection of a related "closed" hairpin loop dimer using proteolytic footprinting.

Speicher DW, DeSilva TM, Speicher KD, Ursitti JA, Hembach P, Weglarz L.

J Biol Chem. 1993 Feb 25;268(6):4227-35.

10.

Spectrin: structure, function and disease.

Zhang R, Zhang C, Zhao Q, Li D.

Sci China Life Sci. 2013 Dec;56(12):1076-85. doi: 10.1007/s11427-013-4575-0. Epub 2013 Dec 5. Review.

PMID:
24302288
11.

Molecular basis of clinical and morphological heterogeneity in hereditary elliptocytosis (HE) with spectrin alpha I variants.

Lecomte MC, Garbarz M, Gautero H, Bournier O, Galand C, Boivin P, Dhermy D.

Br J Haematol. 1993 Nov;85(3):584-95.

PMID:
8136282
12.
13.

Spectrin tetramer formation is not required for viable development in Drosophila.

Khanna MR, Mattie FJ, Browder KC, Radyk MD, Crilly SE, Bakerink KJ, Harper SL, Speicher DW, Thomas GH.

J Biol Chem. 2015 Jan 9;290(2):706-15. doi: 10.1074/jbc.M114.615427. Epub 2014 Nov 7.

15.
16.

Spectrin oligomerization is cooperatively coupled to membrane assembly: a linkage targeted by many hereditary hemolytic anemias?

Giorgi M, Cianci CD, Gallagher PG, Morrow JS.

Exp Mol Pathol. 2001 Jun;70(3):215-30.

PMID:
11418000
18.

Crystal structure of the nonerythroid alpha-spectrin tetramerization site reveals differences between erythroid and nonerythroid spectrin tetramer formation.

Mehboob S, Song Y, Witek M, Long F, Santarsiero BD, Johnson ME, Fung LW.

J Biol Chem. 2010 May 7;285(19):14572-84. doi: 10.1074/jbc.M109.080028. Epub 2010 Mar 14.

19.
20.

Shear-response of the spectrin dimer-tetramer equilibrium in the red blood cell membrane.

An X, Lecomte MC, Chasis JA, Mohandas N, Gratzer W.

J Biol Chem. 2002 Aug 30;277(35):31796-800. Epub 2002 Jun 24.

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