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Items: 1 to 20 of 103

1.

The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometry.

Ablonczy Z, Smith N, Anderson DM, Grey AC, Spraggins J, Koutalos Y, Schey KL, Crouch RK.

Proteomics. 2014 Apr;14(7-8):936-44. doi: 10.1002/pmic.201300406. Epub 2014 Mar 5.

2.

Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium.

Ablonczy Z, Higbee D, Grey AC, Koutalos Y, Schey KL, Crouch RK.

Arch Biochem Biophys. 2013 Nov 15;539(2):196-202. doi: 10.1016/j.abb.2013.08.005. Epub 2013 Aug 19.

3.

Spatial localization of A2E in the retinal pigment epithelium.

Grey AC, Crouch RK, Koutalos Y, Schey KL, Ablonczy Z.

Invest Ophthalmol Vis Sci. 2011 Jun 6;52(7):3926-33. doi: 10.1167/iovs.10-7020.

4.

Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.

Boyer NP, Higbee D, Currin MB, Blakeley LR, Chen C, Ablonczy Z, Crouch RK, Koutalos Y.

J Biol Chem. 2012 Jun 22;287(26):22276-86. doi: 10.1074/jbc.M111.329235. Epub 2012 May 8.

5.

Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium.

Ablonczy Z, Higbee D, Anderson DM, Dahrouj M, Grey AC, Gutierrez D, Koutalos Y, Schey KL, Hanneken A, Crouch RK.

Invest Ophthalmol Vis Sci. 2013 Aug 15;54(8):5535-42. doi: 10.1167/iovs.13-12250.

6.

A2E and Lipofuscin.

Crouch RK, Koutalos Y, Kono M, Schey K, Ablonczy Z.

Prog Mol Biol Transl Sci. 2015;134:449-63. doi: 10.1016/bs.pmbts.2015.06.005. Epub 2015 Jul 14. Review.

PMID:
26310170
7.

A2E and lipofuscin distributions in macaque retinal pigment epithelium are similar to human.

Pallitto P, Ablonczy Z, Jones EE, Drake RR, Koutalos Y, Crouch RK, Donello J, Herrmann J.

Photochem Photobiol Sci. 2015 Oct;14(10):1888-95. doi: 10.1039/c5pp00170f.

8.

Changes in spectral properties and composition of lipofuscin fluorophores from human-retinal-pigment epithelium with age and pathology.

Feldman TB, Yakovleva MA, Arbukhanova PM, Borzenok SA, Kononikhin AS, Popov IA, Nikolaev EN, Ostrovsky MA.

Anal Bioanal Chem. 2015 Feb;407(4):1075-88. doi: 10.1007/s00216-014-8353-z. Epub 2014 Dec 4.

PMID:
25471291
9.

Lipofuscin and A2E accumulate with age in the retinal pigment epithelium of Nrl-/- mice.

Boyer NP, Tang PH, Higbee D, Ablonczy Z, Crouch RK, Koutalos Y.

Photochem Photobiol. 2012 Nov-Dec;88(6):1373-7. doi: 10.1111/j.1751-1097.2012.01127.x. Epub 2012 Mar 28.

10.

Estimation of fluorescence lifetime of lipofuscin fluorophores contained in lipofuscin granules of retinal pigment epithelium of human cadaver eyes without signs of pathology.

Yakovleva MA, Feldman TB, Arbukhanova PM, Borzenok SA, Kuzmin VA, Ostrovsky MA.

Dokl Biochem Biophys. 2017 Jan;472(1):19-22. doi: 10.1134/S1607672917010069. Epub 2017 Apr 19.

PMID:
28421434
11.
12.

Determination of N-retinylidene-N-retinylethanolamine (A2E) levels in central and peripheral areas of human retinal pigment epithelium.

Adler L 4th, Boyer NP, Anderson DM, Spraggins JM, Schey KL, Hanneken A, Ablonczy Z, Crouch RK, Koutalos Y.

Photochem Photobiol Sci. 2015 Nov;14(11):1983-90. doi: 10.1039/c5pp00156k.

13.

Complement system dysregulation and inflammation in the retinal pigment epithelium of a mouse model for Stargardt macular degeneration.

Radu RA, Hu J, Yuan Q, Welch DL, Makshanoff J, Lloyd M, McMullen S, Travis GH, Bok D.

J Biol Chem. 2011 May 27;286(21):18593-601. doi: 10.1074/jbc.M110.191866. Epub 2011 Apr 4.

14.

Molecule-specific imaging and quantitation of A2E in the RPE.

Ablonczy Z, Gutierrez DB, Grey AC, Schey KL, Crouch RK.

Adv Exp Med Biol. 2012;723:75-81. doi: 10.1007/978-1-4614-0631-0_11. No abstract available.

15.

Compositional studies of human RPE lipofuscin: mechanisms of molecular modifications.

Murdaugh LS, Mandal S, Dill AE, Dillon J, Simon JD, Gaillard ER.

J Mass Spectrom. 2011 Jan;46(1):90-5. doi: 10.1002/jms.1865.

PMID:
21182214
16.
17.

Compositional studies of human RPE lipofuscin.

Murdaugh LS, Avalle LB, Mandal S, Dill AE, Dillon J, Simon JD, Gaillard ER.

J Mass Spectrom. 2010 Oct;45(10):1139-47. doi: 10.1002/jms.1795.

PMID:
20860013
18.

Photooxidation of RPE lipofuscin bisretinoids enhances fluorescence intensity.

Kim SR, Jang YP, Sparrow JR.

Vision Res. 2010 Mar 31;50(7):729-36. doi: 10.1016/j.visres.2009.09.015. Epub 2009 Oct 1.

19.

Observation of A2E oxidation products in human retinal lipofuscin.

Avalle LB, Wang Z, Dillon JP, Gaillard ER.

Exp Eye Res. 2004 Apr;78(4):895-8.

PMID:
15037123
20.

Preparative and biosynthetic insights into pdA2E and isopdA2E, retinal-derived fluorophores of retinal pigment epithelial lipofuscin.

Zhao J, Yao K, Jin Q, Jiang K, Chen J, Liu Z, Li J, Wu Y.

Invest Ophthalmol Vis Sci. 2014 Nov 20;55(12):8241-50. doi: 10.1167/iovs.14-15709.

PMID:
25414195

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