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Items: 1 to 20 of 214

1.

FOXO1-dependent DNA damage repair is regulated by JNK in lung cancer cells.

Ju Y, Xu T, Zhang H, Yu A.

Int J Oncol. 2014 Apr;44(4):1284-92. doi: 10.3892/ijo.2014.2269. Epub 2014 Jan 21.

PMID:
24452601
2.

SIRT1 deficiency downregulates PTEN/JNK/FOXO1 pathway to block reactive oxygen species-induced apoptosis in mouse embryonic stem cells.

Chae HD, Broxmeyer HE.

Stem Cells Dev. 2011 Jul;20(7):1277-85. doi: 10.1089/scd.2010.0465. Epub 2011 Jan 3.

3.

Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway.

Zhao Z, Li C, Xi H, Gao Y, Xu D.

Mol Med Rep. 2015 Oct;12(4):5415-22. doi: 10.3892/mmr.2015.4060. Epub 2015 Jul 8.

PMID:
26166196
4.

FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells.

Shukla S, Rizvi F, Raisuddin S, Kakkar P.

Free Radic Biol Med. 2014 Nov;76:185-99. doi: 10.1016/j.freeradbiomed.2014.07.039. Epub 2014 Aug 13.

PMID:
25128467
5.

Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.

Meng Z, Lv J, Luo Y, Lin Y, Zhu Y, Nie J, Yang T, Sun Y, Han X.

Endocrinology. 2009 Dec;150(12):5284-93. doi: 10.1210/en.2009-0671. Epub 2009 Oct 16.

PMID:
19837872
6.

JNK-dependent downregulation of FoxO1 is required to promote the survival of fibroblast-like synoviocytes in rheumatoid arthritis.

Grabiec AM, Angiolilli C, Hartkamp LM, van Baarsen LG, Tak PP, Reedquist KA.

Ann Rheum Dis. 2015 Sep;74(9):1763-71. doi: 10.1136/annrheumdis-2013-203610. Epub 2014 May 8.

PMID:
24812285
7.

Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.

Boreddy SR, Pramanik KC, Srivastava SK.

Clin Cancer Res. 2011 Apr 1;17(7):1784-95. doi: 10.1158/1078-0432.CCR-10-1891. Epub 2011 Feb 24. Erratum in: Clin Cancer Res. 2012 May 1;18(9):2719.

8.

FOXO3a: a novel player in thyroid carcinogenesis?

Karger S, Weidinger C, Krause K, Sheu SY, Aigner T, Gimm O, Schmid KW, Dralle H, Fuhrer D.

Endocr Relat Cancer. 2009 Mar;16(1):189-99. doi: 10.1677/ERC-07-0283. Epub 2008 Oct 9.

9.

Inhibition of H2O2-induced cell death through FOXO1 modulation by EUK-172 in SK-N-MC cells.

Gheysarzadeh A, Yazdanparast R.

Eur J Pharmacol. 2012 Dec 15;697(1-3):47-52. doi: 10.1016/j.ejphar.2012.09.036. Epub 2012 Oct 3.

PMID:
23041154
10.

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2.

Stahl M, Dijkers PF, Kops GJ, Lens SM, Coffer PJ, Burgering BM, Medema RH.

J Immunol. 2002 May 15;168(10):5024-31.

11.

BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells.

Banerji L, Glassford J, Lea NC, Thomas NS, Klaus GG, Lam EW.

Oncogene. 2001 Nov 1;20(50):7352-67.

12.

MicroRNA-21 plays an oncogenic role by targeting FOXO1 and activating the PI3K/AKT pathway in diffuse large B-cell lymphoma.

Go H, Jang JY, Kim PJ, Kim YG, Nam SJ, Paik JH, Kim TM, Heo DS, Kim CW, Jeon YK.

Oncotarget. 2015 Jun 20;6(17):15035-49.

13.

Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma.

Wang JG, Zheng XX, Zeng GY, Zhou YJ, Yuan H.

Oncol Rep. 2014 Jan;31(1):488-96. doi: 10.3892/or.2013.2855. Epub 2013 Nov 15.

PMID:
24247909
14.

Transcriptional and post-translational regulation of Bim is essential for TGF-β and TNF-α-induced apoptosis of gastric cancer cell.

Ha Thi HT, Lim HS, Kim J, Kim YM, Kim HY, Hong S.

Biochim Biophys Acta. 2013 Jun;1830(6):3584-92. doi: 10.1016/j.bbagen.2013.03.006. Epub 2013 Mar 15.

PMID:
23500081
15.

The function of FOXO1 in the late phases of the cell cycle is suppressed by PLK1-mediated phosphorylation.

Yuan C, Wang L, Zhou L, Fu Z.

Cell Cycle. 2014;13(5):807-19. doi: 10.4161/cc.27727. Epub 2014 Jan 9.

17.

Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.

Sah JF, Balasubramanian S, Eckert RL, Rorke EA.

J Biol Chem. 2004 Mar 26;279(13):12755-62. Epub 2003 Dec 29.

18.

Nuclear forkhead box O1 controls and integrates key signaling pathways in hepatocytes.

Naïmi M, Gautier N, Chaussade C, Valverde AM, Accili D, Van Obberghen E.

Endocrinology. 2007 May;148(5):2424-34. Epub 2007 Feb 15. Erratum in: Endocrinology. 2007 Jul;148(7):3517.

PMID:
17303659
19.

CHIP regulates AKT/FoxO/Bim signaling in MCF7 and MCF10A cells.

Lv Y, Song S, Zhang K, Gao H, Ma R.

PLoS One. 2013 Dec 20;8(12):e83312. doi: 10.1371/journal.pone.0083312. eCollection 2013.

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