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Items: 1 to 20 of 103

1.

Molecular profiling of chordoma.

Scheil-Bertram S, Kappler R, von Baer A, Hartwig E, Sarkar M, Serra M, Brüderlein S, Westhoff B, Melzner I, Bassaly B, Herms J, Hugo HH, Schulte M, Möller P.

Int J Oncol. 2014 Apr;44(4):1041-55. doi: 10.3892/ijo.2014.2268.

2.

[Novel molecular aspects of chordomas].

Scheil-Bertram S.

Pathologe. 2014 Nov;35 Suppl 2:237-41. doi: 10.1007/s00292-014-1986-z. German.

PMID:
25394972
3.

Chordoma and chondrosarcoma gene profile: implications for immunotherapy.

Schwab JH, Boland PJ, Agaram NP, Socci ND, Guo T, O'Toole GC, Wang X, Ostroumov E, Hunter CJ, Block JA, Doty S, Ferrone S, Healey JH, Antonescu CR.

Cancer Immunol Immunother. 2009 Mar;58(3):339-49. doi: 10.1007/s00262-008-0557-7.

4.

Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target.

Hsu W, Mohyeldin A, Shah SR, ap Rhys CM, Johnson LF, Sedora-Roman NI, Kosztowski TA, Awad OA, McCarthy EF, Loeb DM, Wolinsky JP, Gokaslan ZL, Quiñones-Hinojosa A.

J Neurosurg. 2011 Oct;115(4):760-9. doi: 10.3171/2011.5.JNS11185.

5.
6.

An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma.

Nelson AC, Pillay N, Henderson S, Presneau N, Tirabosco R, Halai D, Berisha F, Flicek P, Stemple DL, Stern CD, Wardle FC, Flanagan AM.

J Pathol. 2012 Nov;228(3):274-85. doi: 10.1002/path.4082.

PMID:
22847733
7.

Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines.

Karikari IO, Gilchrist CL, Jing L, Alcorta DA, Chen J, Richardson WJ, Gabr MA, Bell RD, Kelley MJ, Bagley CA, Setton LA.

J Neurosurg Spine. 2014 Sep;21(3):386-93. doi: 10.3171/2014.4.SPINE13262.

8.

Genome-wide analysis of sixteen chordomas by comparative genomic hybridization and cytogenetics of the first human chordoma cell line, U-CH1.

Scheil S, Brüderlein S, Liehr T, Starke H, Herms J, Schulte M, Möller P.

Genes Chromosomes Cancer. 2001 Nov;32(3):203-11.

PMID:
11579460
9.

Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study.

Presneau N, Shalaby A, Ye H, Pillay N, Halai D, Idowu B, Tirabosco R, Whitwell D, Jacques TS, Kindblom LG, Brüderlein S, Möller P, Leithner A, Liegl B, Amary FM, Athanasou NN, Hogendoorn PC, Mertens F, Szuhai K, Flanagan AM.

J Pathol. 2011 Feb;223(3):327-35. doi: 10.1002/path.2816.

PMID:
21171078
10.

Brachyury and chordoma: the chondroid-chordoid dilemma resolved?

Romeo S, Hogendoorn PC.

J Pathol. 2006 Jun;209(2):143-6.

PMID:
16604512
11.

Molecular and clinical risk factors for recurrence of skull base chordomas: gain on chromosome 2p, expression of brachyury, and lack of irradiation negatively correlate with patient prognosis.

Kitamura Y, Sasaki H, Kimura T, Miwa T, Takahashi S, Kawase T, Yoshida K.

J Neuropathol Exp Neurol. 2013 Sep;72(9):816-23. doi: 10.1097/NEN.0b013e3182a065d0.

PMID:
23965741
12.

T gene isoform expression pattern is significantly different between chordomas and notochords.

Wang K, Hu Q, Wang L, Chen W, Tian K, Cao C, Wu Z, Jia G, Zhang L, Zeng C, Zhang J.

Biochem Biophys Res Commun. 2015 Nov 13;467(2):261-7. doi: 10.1016/j.bbrc.2015.09.178.

PMID:
26435504
13.

P63 does not regulate brachyury expression in human chordomas and osteosarcomas.

Pillay N, Amary FM, Berisha F, Tirabosco R, Flanagan AM.

Histopathology. 2011 Nov;59(5):1025-7. doi: 10.1111/j.1365-2559.2011.03973.x. No abstract available.

PMID:
22007675
14.

'The chicken or the egg?' dilemma strikes back for the controlling mechanism in chordoma(#).

Szuhai K, Hogendoorn PC.

J Pathol. 2012 Nov;228(3):261-5. doi: 10.1002/path.4102.

PMID:
22952146
15.

Novel therapeutic targets in chordoma.

Bydon M, Papadimitriou K, Witham T, Wolinsky JP, Bydon A, Sciubba D, Gokaslan Z.

Expert Opin Ther Targets. 2012 Nov;16(11):1139-43. doi: 10.1517/14728222.2012.714772. Review.

PMID:
22860993
16.

New candidate chromosomal regions for chordoma development.

Bayrakli F, Guney I, Kilic T, Ozek M, Pamir MN.

Surg Neurol. 2007 Oct;68(4):425-30; discussion 430.

PMID:
17714767
17.

Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas.

Vujovic S, Henderson S, Presneau N, Odell E, Jacques TS, Tirabosco R, Boshoff C, Flanagan AM.

J Pathol. 2006 Jun;209(2):157-65.

PMID:
16538613
18.

Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group.

Tallini G, Dorfman H, Brys P, Dal Cin P, De Wever I, Fletcher CD, Jonson K, Mandahl N, Mertens F, Mitelman F, Rosai J, Rydholm A, Samson I, Sciot R, Van den Berghe H, Vanni R, Willén H.

J Pathol. 2002 Feb;196(2):194-203. Review.

PMID:
11793371
19.

Distinguishing chordoid meningiomas from their histologic mimics: an immunohistochemical evaluation.

Sangoi AR, Dulai MS, Beck AH, Brat DJ, Vogel H.

Am J Surg Pathol. 2009 May;33(5):669-81. doi: 10.1097/PAS.0b013e318194c566.

20.

From notochord formation to hereditary chordoma: the many roles of Brachyury.

Nibu Y, José-Edwards DS, Di Gregorio A.

Biomed Res Int. 2013;2013:826435. doi: 10.1155/2013/826435. Review.

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