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Items: 1 to 20 of 111

1.

Atorvastatin prevents ATP-driven invasiveness via P2X7 and EHBP1 signaling in PTEN-expressing prostate cancer cells.

Ghalali A, Wiklund F, Zheng H, Stenius U, Högberg J.

Carcinogenesis. 2014 Jul;35(7):1547-55. doi: 10.1093/carcin/bgu019.

PMID:
24451147
2.

Statins and ATP regulate nuclear pAkt via the P2X7 purinergic receptor in epithelial cells.

Mistafa O, Högberg J, Stenius U.

Biochem Biophys Res Commun. 2008 Jan 4;365(1):131-6.

PMID:
17980145
3.
4.

Statins inhibit Akt/PKB signaling via P2X7 receptor in pancreatic cancer cells.

Mistafa O, Stenius U.

Biochem Pharmacol. 2009 Nov 1;78(9):1115-26. doi: 10.1016/j.bcp.2009.06.016.

PMID:
19540829
5.

Statins exhibit anticancer effects through modifications of the pAkt signaling pathway.

Miraglia E, Högberg J, Stenius U.

Int J Oncol. 2012 Mar;40(3):867-75. doi: 10.3892/ijo.2011.1223.

PMID:
21994073
6.

Silencing p110β prevents rapid depletion of nuclear pAkt.

Ye ZW, Ghalali A, Högberg J, Stenius U.

Biochem Biophys Res Commun. 2011 Dec 2;415(4):613-8. doi: 10.1016/j.bbrc.2011.10.120.

PMID:
22074824
7.

P2X7 mediates ATP-driven invasiveness in prostate cancer cells.

Qiu Y, Li WH, Zhang HQ, Liu Y, Tian XX, Fang WG.

PLoS One. 2014 Dec 8;9(12):e114371. doi: 10.1371/journal.pone.0114371. Erratum in: PLoS One. 2015;10(4):e0123388.

8.

Cytosolic phospholipase A2α sustains pAKT, pERK and AR levels in PTEN-null/mutated prostate cancer cells.

Hua S, Yao M, Vignarajan S, Witting P, Hejazi L, Gong Z, Teng Y, Niknami M, Assinder S, Richardson D, Dong Q.

Biochim Biophys Acta. 2013 Jun;1831(6):1146-57. doi: 10.1016/j.bbalip.2013.02.011.

PMID:
23500889
9.

Inhibitory effect of atorvastatin on the cell growth of cardiac myxomas via the PTEN and PHLPP2 phosphatase signaling pathway.

Wu XL, Yang DY, Tan DJ, Yao HC, Chai W, Peng L.

Oncol Rep. 2013 Aug;30(2):757-62. doi: 10.3892/or.2013.2501.

PMID:
23715723
10.

Inhibition of serotonin-induced mitogenesis, migration, and ERK MAPK nuclear translocation in vascular smooth muscle cells by atorvastatin.

Li M, Liu Y, Dutt P, Fanburg BL, Toksoz D.

Am J Physiol Lung Cell Mol Physiol. 2007 Aug;293(2):L463-71.

12.

Pleiotropic role of atorvastatin in regulation of human retinal pigment epithelial cell behaviors in vitro.

Wu WC, Lai YH, Hsieh MC, Chang YC, Wu MH, Wu HJ, Chang CW, Wu KY, Kao YH.

Exp Eye Res. 2011 Dec;93(6):842-51. doi: 10.1016/j.exer.2011.09.016.

PMID:
21989109
13.

P2X7 receptor stimulates breast cancer cell invasion and migration via the AKT pathway.

Xia J, Yu X, Tang L, Li G, He T.

Oncol Rep. 2015 Jul;34(1):103-10. doi: 10.3892/or.2015.3979.

PMID:
25976617
14.

Atorvastatin inhibits GSK-3beta phosphorylation by cardiac hypertrophic stimuli.

Planavila A, Rodríguez-Calvo R, Palomer X, Coll T, Sánchez RM, Merlos M, Laguna JC, Vázquez-Carrera M.

Biochim Biophys Acta. 2008 Jan-Feb;1781(1-2):26-35.

PMID:
18036354
15.

Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion.

Shukla S, Maclennan GT, Hartman DJ, Fu P, Resnick MI, Gupta S.

Int J Cancer. 2007 Oct 1;121(7):1424-32.

16.

Atorvastatin inhibited Rho-associated kinase 1 (ROCK1) and focal adhesion kinase (FAK) mediated adhesion and differentiation of CD133+CD44+ prostate cancer stem cells.

Rentala S, Chintala R, Guda M, Chintala M, Komarraju AL, Mangamoori LN.

Biochem Biophys Res Commun. 2013 Nov 22;441(3):586-92. doi: 10.1016/j.bbrc.2013.10.112.

PMID:
24177008
17.

Mechanism of the inhibitory effect of atorvastatin on endoglin expression induced by transforming growth factor-beta1 in cultured cardiac fibroblasts.

Shyu KG, Wang BW, Chen WJ, Kuan P, Hung CR.

Eur J Heart Fail. 2010 Mar;12(3):219-26. doi: 10.1093/eurjhf/hfq011.

18.

Atorvastatin enhances neurite outgrowth in cortical neurons in vitro via up-regulating the Akt/mTOR and Akt/GSK-3β signaling pathways.

Jin Y, Sui HJ, Dong Y, Ding Q, Qu WH, Yu SX, Jin YX.

Acta Pharmacol Sin. 2012 Jul;33(7):861-72. doi: 10.1038/aps.2012.59.

19.

Atorvastatin inhibits RhoC function and limits head and neck cancer metastasis.

Islam M, Sharma S, Kumar B, Teknos TN.

Oral Oncol. 2013 Aug;49(8):778-86. doi: 10.1016/j.oraloncology.2013.04.003.

20.

CXCR4 and PTEN are involved in the anti-metastatic regulation of anethole in DU145 prostate cancer cells.

Rhee YH, Chung PS, Kim SH, Ahn JC.

Biochem Biophys Res Commun. 2014 May 16;447(4):557-62. doi: 10.1016/j.bbrc.2014.01.121.

PMID:
24525130

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