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Items: 1 to 20 of 101

1.

Synthesis of full length and truncated microcin B17 analogues as DNA gyrase poisons.

Thompson RE, Collin F, Maxwell A, Jolliffe KA, Payne RJ.

Org Biomol Chem. 2014 Mar 14;12(10):1570-8. doi: 10.1039/c3ob42516a.

PMID:
24448886
2.

In vitro characterization of DNA gyrase inhibition by microcin B17 analogs with altered bisheterocyclic sites.

Zamble DB, Miller DA, Heddle JG, Maxwell A, Walsh CT, Hollfelder F.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7712-7. Epub 2001 Jun 26.

3.

The action of the bacterial toxin microcin B17. Insight into the cleavage-religation reaction of DNA gyrase.

Pierrat OA, Maxwell A.

J Biol Chem. 2003 Sep 12;278(37):35016-23. Epub 2003 Jun 25.

4.

Evidence for the role of DNA strand passage in the mechanism of action of microcin B17 on DNA gyrase.

Pierrat OA, Maxwell A.

Biochemistry. 2005 Mar 22;44(11):4204-15.

PMID:
15766248
5.

The action of the bacterial toxin, microcin B17, on DNA gyrase.

Parks WM, Bottrill AR, Pierrat OA, Durrant MC, Maxwell A.

Biochimie. 2007 Apr;89(4):500-7. Epub 2006 Dec 31.

PMID:
17276574
6.

Total synthesis of microcin B17 via a fragment condensation approach.

Thompson RE, Jolliffe KA, Payne RJ.

Org Lett. 2011 Feb 18;13(4):680-3. doi: 10.1021/ol102916b. Epub 2011 Jan 14.

PMID:
21235262
7.
8.

The antibiotic microcin B17 is a DNA gyrase poison: characterisation of the mode of inhibition.

Heddle JG, Blance SJ, Zamble DB, Hollfelder F, Miller DA, Wentzell LM, Walsh CT, Maxwell A.

J Mol Biol. 2001 Apr 13;307(5):1223-34.

PMID:
11292337
9.

From peptide precursors to oxazole and thiazole-containing peptide antibiotics: microcin B17 synthase.

Li YM, Milne JC, Madison LL, Kolter R, Walsh CT.

Science. 1996 Nov 15;274(5290):1188-93.

PMID:
8895467
10.

Posttranslational modifications in microcin B17 define an additional class of DNA gyrase inhibitor.

Yorgey P, Lee J, Kördel J, Vivas E, Warner P, Jebaratnam D, Kolter R.

Proc Natl Acad Sci U S A. 1994 May 10;91(10):4519-23.

11.

The peptide antibiotic microcin B17 induces double-strand cleavage of DNA mediated by E. coli DNA gyrase.

Vizán JL, Hernández-Chico C, del Castillo I, Moreno F.

EMBO J. 1991 Feb;10(2):467-76.

13.

Fragments of the bacterial toxin microcin B17 as gyrase poisons.

Collin F, Thompson RE, Jolliffe KA, Payne RJ, Maxwell A.

PLoS One. 2013 Apr 10;8(4):e61459. doi: 10.1371/journal.pone.0061459. Print 2013.

14.

Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase.

Ronkin SM, Badia M, Bellon S, Grillot AL, Gross CH, Grossman TH, Mani N, Parsons JD, Stamos D, Trudeau M, Wei Y, Charifson PS.

Bioorg Med Chem Lett. 2010 May 1;20(9):2828-31. doi: 10.1016/j.bmcl.2010.03.052. Epub 2010 Mar 15.

PMID:
20356737
15.

The leader peptide is essential for the post-translational modification of the DNA-gyrase inhibitor microcin B17.

Madison LL, Vivas EI, Li YM, Walsh CT, Kolter R.

Mol Microbiol. 1997 Jan;23(1):161-8.

16.

Effect of different classes of inhibitors on DNA gyrase from Mycobacterium smegmatis.

Chatterji M, Unniraman S, Mahadevan S, Nagaraja V.

J Antimicrob Chemother. 2001 Oct;48(4):479-85.

PMID:
11581225
17.
18.

Kinetics and regioselectivity of peptide-to-heterocycle conversions by microcin B17 synthetase.

Belshaw PJ, Roy RS, Kelleher NL, Walsh CT.

Chem Biol. 1998 Jul;5(7):373-84.

19.

Pyrrolamide DNA gyrase inhibitors: optimization of antibacterial activity and efficacy.

Sherer BA, Hull K, Green O, Basarab G, Hauck S, Hill P, Loch JT 3rd, Mullen G, Bist S, Bryant J, Boriack-Sjodin A, Read J, DeGrace N, Uria-Nickelsen M, Illingworth RN, Eakin AE.

Bioorg Med Chem Lett. 2011 Dec 15;21(24):7416-20. doi: 10.1016/j.bmcl.2011.10.010. Epub 2011 Oct 12.

PMID:
22041057
20.

A major portion of DNA gyrase inhibitor microcin B17 undergoes an N,O-peptidyl shift during synthesis.

Ghilarov D, Serebryakova M, Shkundina I, Severinov K.

J Biol Chem. 2011 Jul 29;286(30):26308-18. doi: 10.1074/jbc.M111.241315. Epub 2011 May 31.

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