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Items: 1 to 20 of 117

1.

Exendin-4 attenuates endoplasmic reticulum stress through a SIRT1-dependent mechanism.

Lee J, Hong SW, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY.

Cell Stress Chaperones. 2014 Sep;19(5):649-56. doi: 10.1007/s12192-013-0490-3. Epub 2014 Jan 21.

2.

Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice.

Lee J, Hong SW, Chae SW, Kim DH, Choi JH, Bae JC, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Kim SW, Lee WY.

PLoS One. 2012;7(2):e31394. doi: 10.1371/journal.pone.0031394. Epub 2012 Feb 17.

3.

Exendin-4 inhibits glucolipotoxic ER stress in pancreatic β cells via regulation of SREBP1c and C/EBPβ transcription factors.

Oh YS, Lee YJ, Kang Y, Han J, Lim OK, Jun HS.

J Endocrinol. 2013 Feb 25;216(3):343-52. doi: 10.1530/JOE-12-0311. Print 2013 Mar.

4.

Exendin-4 attenuates high glucose-induced cardiomyocyte apoptosis via inhibition of endoplasmic reticulum stress and activation of SERCA2a.

Younce CW, Burmeister MA, Ayala JE.

Am J Physiol Cell Physiol. 2013 Mar;304(6):C508-18. doi: 10.1152/ajpcell.00248.2012. Epub 2013 Jan 9.

5.

SIRT1/HSF1/HSP pathway is essential for exenatide-alleviated, lipid-induced hepatic endoplasmic reticulum stress.

Zheng X, Xu F, Liang H, Cao H, Cai M, Xu W, Weng J.

Hepatology. 2017 Sep;66(3):809-824. doi: 10.1002/hep.29238. Epub 2017 Jul 20.

PMID:
28439947
6.

Role of ERp46 in β-cell lipoapoptosis through endoplasmic reticulum stress pathway as well as the protective effect of exendin-4.

Chen DL, Xiang JN, Yang LY.

Biochem Biophys Res Commun. 2012 Sep 28;426(3):324-9. doi: 10.1016/j.bbrc.2012.08.072. Epub 2012 Aug 23.

PMID:
22935416
7.

The resveratrol attenuates ethanol-induced hepatocyte apoptosis via inhibiting ER-related caspase-12 activation and PDE activity in vitro.

Liu LQ, Fan ZQ, Tang YF, Ke ZJ.

Alcohol Clin Exp Res. 2014 Mar;38(3):683-93. doi: 10.1111/acer.12311. Epub 2013 Nov 13.

PMID:
24224909
8.

Protection of pancreatic beta-cells by exendin-4 may involve the reduction of endoplasmic reticulum stress; in vivo and in vitro studies.

Tsunekawa S, Yamamoto N, Tsukamoto K, Itoh Y, Kaneko Y, Kimura T, Ariyoshi Y, Miura Y, Oiso Y, Niki I.

J Endocrinol. 2007 Apr;193(1):65-74.

9.

GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy.

Sharma S, Mells JE, Fu PP, Saxena NK, Anania FA.

PLoS One. 2011;6(9):e25269. doi: 10.1371/journal.pone.0025269. Epub 2011 Sep 21.

10.
11.

Ethanol promotes saturated fatty acid-induced hepatoxicity through endoplasmic reticulum (ER) stress response.

Yi HW, Ma YX, Wang XN, Wang CF, Lu J, Cao W, Wu XD.

Chin J Nat Med. 2015 Apr;13(4):250-6. doi: 10.1016/S1875-5364(15)30011-X.

PMID:
25908621
12.
13.

[The influence of patatin-like phospholipase domain-containing protein 3 on palmitic acid-induced hepatocyte apoptosis].

Yuan SH, Liang H, Cai MY, Xu F, Yuan D, Zheng XB, Li M, Weng JP.

Zhonghua Yi Xue Za Zhi. 2016 May 24;96(19):1535-9. doi: 10.3760/cma.j.issn.0376-2491.2016.19.016. Chinese.

PMID:
27266503
14.

HIF-1α expression as a protective strategy of HepG2 cells against fatty acid-induced toxicity.

Yoo W, Noh KH, Ahn JH, Yu JH, Seo JA, Kim SG, Choi KM, Baik SH, Choi DS, Kim TW, Kim HJ, Kim NH.

J Cell Biochem. 2014 Jun;115(6):1147-58. doi: 10.1002/jcb.24757.

PMID:
24402912
15.

Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

Cunha DA, Ladrière L, Ortis F, Igoillo-Esteve M, Gurzov EN, Lupi R, Marchetti P, Eizirik DL, Cnop M.

Diabetes. 2009 Dec;58(12):2851-62. doi: 10.2337/db09-0685. Epub 2009 Aug 31.

16.

Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation.

Li J, Dou X, Li S, Zhang X, Zeng Y, Song Z.

Biochim Biophys Acta. 2015 Nov;1853(11 Pt A):2929-36. doi: 10.1016/j.bbamcr.2015.09.003. Epub 2015 Sep 6.

18.

C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis.

Rahman K, Liu Y, Kumar P, Smith T, Thorn NE, Farris AB, Anania FA.

Lab Invest. 2016 Aug;96(8):895-908. doi: 10.1038/labinvest.2016.61. Epub 2016 May 30.

19.

Exendin-4 regulates lipid metabolism and fibroblast growth factor 21 in hepatic steatosis.

Lee J, Hong SW, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY.

Metabolism. 2014 Aug;63(8):1041-8. doi: 10.1016/j.metabol.2014.04.011. Epub 2014 May 6.

PMID:
24933399
20.

Exendin-4 Inhibits the Expression of SEPP1 and Fetuin-A via Improvement of Palmitic Acid-Induced Endoplasmic Reticulum Stress by AMPK.

Lee J, Hong SW, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY.

Endocrinol Metab (Seoul). 2015 Jun;30(2):177-84. doi: 10.3803/EnM.2015.30.2.177. Epub 2014 Jul 2.

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